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| Aliases | ADCK2 , AARF, aarF domain containing kinase 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | MGI: 1889336 HomoloGene: 49103 GeneCards: ADCK2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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ADCK2 (aarF domain containing kinase 2) is an enzyme that in humans is encoded by the ADCK2 gene. It is situated on chromosome 7 at the q34 location.
ADCK2 is predicted to possess ATP binding activity and protein serine/threonine kinase activity. The protein is predicted to be an integral part of the membrane. [5]
The ADCK2 gene is located on chromosome 7q34. The genomic sequence spans 22,165 base pairs from 140,672,945 to 140,695,110 on the GRCh38.p14 primary assembly. It consists of 8 exons. [5]
ADCK2 is ubiquitously expressed across various human tissues, with notable expression in skin and brain tissue, among others. [5]
Research indicates that ADCK2 may have therapeutic implications in diseases such as myopathy. [6]
FYVE, RhoGEF and PH domain-containing protein 4 is a protein encoded in humans by the FGD4 gene.
Mitogen-activated protein kinase kinase kinase 9 is an enzyme that in humans is encoded by the MAP3K9 gene.
Gene C11orf16, chromosome 11 open reading frame 16, is a protein in humans that is encoded by the C11orf16 gene. It has 7 exons, and the size of 467 amino acids.
aarF domain containing kinase 3 is a protein that in humans is encoded by the ADCK3 gene.
Dual specificity protein phosphatase 12 is an enzyme that in humans is encoded by the DUSP12 gene.
C2CD4D, or C2 calcium-dependent domain-containing protein 4D is a protein product of the human genome. The gene that codes for this protein is found on chromosome 1, from 150,076,963 to 150,079,657. The gene contains 2 exons and encodes 353 amino acids. Synonyms for C2CD4D are "FAM148D" and NP_001129475. C2CD4D contains a conserved metal binding domain that is a known as Protein kinase C conserved region 2, subgroup 1. This motif is known to be a member of the C2 superfamily, which is present in phospholipases, protein kinases C, and synaptotagmins. The amino acid sequence of C2CD4D can be accessed at Prior to any post translational modification, C2CD4D has a molecular weight of 37.6 kdal. Although scientists have not yet determined where C2CD4D functions within the cell, C2CD4D has a predicted isoelectric point of 11.636 which severely limits the places in which it can be effective. In addition, C2CD4D does not contain any predicted transmembrane domains or any predicted signal peptides.
Coiled coil domain containing 90B, also known as CCDC90B, is a protein encoded by the CCDC90B gene.
FAM107B is a gene found in humans. It is located on the minus strand of chromosome 10, p13, which is on the short arm of the chromosome. It has other alias names, such as C10orf45, FLJ45505, MGC11034 and MGC90261. The gene contains a conserved domain, DUF1151, which is a family that consists of several eukaryotic proteins of unknown function. FAM107B is expressed in most tissues in the human body without there being a high frequency in any one tissue. It is found in all stages of human development.
The Coiled-Coil Domain Containing Protein – 25 (CCDC25) is a human protein whose function is not presently understood.
Family with sequence similarity 18 member B1 (FAM18B1) is the hypothetical protein encoded by the gene LOC51030. Evidence for this protein only exists at the transcript level. The gene is found on chromosome 17 on the cytogenetic band 17p11.2.
Coiled-coil domain-containing 78 (CCDC78) is a protein in humans encoded by the CCDC78 gene. It has several aliases including C16orf25, FLJ34512, CNM4, and JFP10. It is located on the (-) strand on chromosome 16 (16p13.3). Its gene neighborhood includes NARFL, HAGHL, FAM173A, and METRN. The CCDC78 gene is 10,892 base pairs long, and the protein contains 438 amino acids. The protein weighs approximately 4.852 KDal. There are several isoforms, including one indicated with a unique congenital myopathy. Several expression profiles show it has ubiquitous expression at moderate levels. Although no paralogs exist several orthologs do.
TMEM106C is a gene that encodes the transmembrane protein 106C (TMEM106C) in Homo sapiens It has been found to be overexpressed in cancer cells and also is related to distal arthrogryposis, a condition of stiff joints and irregular muscle development. The TMEM106C gene contains a domain of unknown function, DUF1356, that spans most of the protein. Transmembrane protein 106C also goes by the aliases MGC5576 or MGC111210, LOC79022.
FAST kinase domain-containing protein 5 (FASTKD5) is a protein that in humans is encoded by the FASTKD5 gene on chromosome 20. This protein is part of the FASTKD family, which is known for regulating the energy balance of mitochondria under stress. FASTKD5 is also required for RNA granules to process precursor mRNAs not flanked by tRNAs.
Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein.
Janus kinase and microtubule interacting protein 2 is a protein that in humans is encoded by the JAKMIP2 gene.
Dual specificity phosphatase 8 is a protein that in humans is encoded by the DUSP8 gene.
Pyridine nucleotide-disulphide oxidoreductase domain 1 is a protein that in humans is encoded by the PYROXD1 gene.
Coiled-coil domain-containing 184 (CCDC184) is a protein which, in humans, is encoded by the CCDC184 gene
ADCK1 is an enzyme that in humans is encoded by the ADCK1 gene. It is situated on chromosome 14 at the q24.3 location.
ADCK5 is an enzyme that in humans is encoded by the ADCK5 gene. It is situated on chromosome 8 at the q24.3 location.
