Dental anesthesia

Last updated
Dental anesthesia
Specialty dental anesthesiology
MeSH D000766

Dental anesthesia (or dental anaesthesia) is the application of anesthesia to dentistry. It includes local anesthetics, sedation, and general anesthesia.

Contents

Local anesthetic agents in dentistry

In dentistry, local anesthetic medications (LA) are often used to control any potential pain that may occur with procedures. [1] Local anesthetic injections are given in specific areas of the mouth, rather than the whole body. Although several different medications are available, the most commonly used local anesthetic to prevent pain in the area around a tooth is lidocaine (also called xylocaine or lignocaine). Lidocaine's half-life in the body is about 1.5–2 hours. [2] The time it takes for the anesthetic medication to prevent pain in the area (speed of onset) and length of time that the area does not have painful sensations are considerations when choosing an appropriate approach to dental treatment. Other considerations include procedural considerations, the presence of inflammation, techniques used to administer the anesthetic medication, and adverse effects. [1] In root canal treatment, for example, more Lidocaine is required than for a simple filling. [2]

Other local anesthetic agents in current use include articaine (also called septocaine or Ubistesin), bupivacaine (a long-acting anesthetic), prilocaine (also called Citanest), and mepivacaine (also called Carbocaine or Polocaine). Different types of local anaesthetic drugs vary in their potency and duration of action. A combination of these may be used depending on the situation. Some agents come in two forms: with and without epinephrine (adrenaline) or other vasoconstrictor that allow the agent to last longer. This controls bleeding in the tissue during procedures. Usually the case is classified using the ASA Physical Status Classification System before any anesthesia is given.[ citation needed ]

Drugs with a short duration of action (approximately 30 minutes of pulpal anaesthesia) include Mepivacaine HCl 3%, and Prilocaine HCl 4% without vasoconstrictor. [3]

Drugs with an intermediate duration of action (enabling pulpal anaesthesia for roughly 60 minutes) include Articaine HCl 4% + epinephrin 1:100,000, Articaine HCl 4% + epinephrin 1:200,000, Lidocaine HCl 2% + epinephrine 1:50,000, Lidocaine HCl 2% + epinephrine 1:80,000; Lidocaine HCl 2% + epinephrine 1:100,000 and Prilocaine HCl 4% + epinephrine 1:200,000. [3]

Bupivicaine HCl 0.5% + epinephrine 1:200,000 gives a long duration of action of pulpal anaesthesia at more than 90 minutes. [3]

Multiple factors affect the depth and duration of local anaesthetics' action. Examples of these factors include the patients individual response to the drug, vascularity and pH of tissues at the site of drug administration, the type of injection administered etc. [3] Hence figures citing the duration of action of local anaesthetics is an approximation, as extreme variations may occur among patients.

Commercially used LA in dental practice has a low pH of 3–4, this is advantageous as it will extend the shelf life of the product and prevent early oxidation. However, low pH LA's may produce a burning sensation, have a slower onset and decrease clinical efficacy. The pH of Local anaesthetic can be increased to increase alkalinity using sodium bicarbonate which reduces pain at the injection site and produces a faster onset. Buffered local anaesthetics have a 2.29 times increased success rate compared with non buffered solutions. [4]

Maxillary anaesthesia

Local anaesthesia is deposited at the buccal (cheek) side of the maxillary alveolus which can diffuse through the thin cortical plate of the maxilla, then further into the pulp of the tooth in order to achieve dental anaesthesia effect.

Karpulenspritze.jpg

Mandibular anaesthesia

Both regional block and infiltration techniques are considered the first choice injections for anaesthetising the mandibular teeth.

Different techniques are chosen based on different factors:

  1. Patient age [5]
    • Infiltration anaesthesia is a preferable method to anaesthetise deciduous/primary teeth in children. The method is similar to the maxillary buccal infiltration. Ensure the lip/ cheek is stretched in a lateral and inferior direction instead of superiorly and the needle is then penetrated 45' with the buccal cortical plate of the bone through the taut tissue of the muccobuccal fold.
  2. Tooth to be anaesthetised [5]
    • Infiltration anaesthesia should be the first choice of method for pulpal and soft tissue anaesthesia of mandibular permanent incisors in adults. Regional block injections are sometimes ineffective due to crossover innervation from the opposite side of inferior alveolar nerve. It is recommended to deposit at least 0.5mL at each buccal and lingual site in the apical region of the tooth of interest. The use of infiltration anaesthesia with 4% articaine with 1:100,000 epinephrine in obtaining pulp anaesthesia of the mandibular permanent first molar is getting more common these days due to its successful formulation.

Regional block techniques

Inferior alveolar and lingual block

The inferior alveolar nerve block is probably one of the most common methods used by dentist to anaesthetise the mandibular teeth in adults. This technique aims to inject the needle and deposit local anaesthetic close to the nerve before it enters the mandibular foramen, which locates on the medial aspect of the mandibular ramus. This is to block the nerve transmission in the inferior alveolar nerve before entering into the bone through the mandibular foramen. [6]

Long buccal nerve block

[5] [7] [8]

Supplementary Techniques

Intraosseous

Intraosseous anaesthesia is an alternative anaesthetic injection technique that was first published in 1910. [9] Intraosseous anaesthetic injection involves the deposition of anaesthetic solution directly into the cancellous alveolar bone adjacent to the apex of the root of the tooth to be anaesthetised through a small hole. Additionally, more complex dental procedures like surgery or endodontic therapy (like root canals) might make use of it.

Intraligamentary

Intraligamentary or periodontal ligament anaesthesia is a technique used primarily for endodontic treatment and to supplement inferior dental blocks where they may have failed. This technique involves 'the deposition of at least 0.2ml of local anaesthetic solution for each root of the tooth' [10] diffusing into the marrow spaces surrounding the teeth. Clinicians may adopt this technique due to some benefits such as: no soft tissue anaesthesia, use of a smaller amount of anaesthetic and single tooth anaesthesia however use may be contraindicated due to claims that patients report sharp pain upon administration of interligamentary aesthetic. However the use of a high-pressure syringe and ultra fine needle provide both chemical anaesthesia (by action of anaesthetic agent) and mechanical anaesthesia (by pressure from deposition). Interligamentary anaesthetic may be complicated by poor operator technique where rapid injection and excessive volume is used; this could lead to sensitivity to biting and percussion. [11]

Research has shown that the rate of onset of anaesthesia in the patients was between 15 and 20 second; this provides an advantage compared to that of inferior alveolar dental block. [12] Other advantages include a decrease in overall trauma in comparison to conventional blocks therefore being an ideal procedure for extractions and endodontic treatment in children.

Intrapulpal

Intrapulpal anaesthesia involves the direct placement of anaesthetic agent using a small needle (of 25 or 27 gauge) into the pulp chamber; it is injected under pressure leading to brief yet intense discomfort. This particular technique provides effective pulpal anaesthesia as the pulpal tissue is subject to chemical action by the anaesthetic agent and mechanical stimulus due to the pressure applied. [11] This method is usually adopted when all other techniques have been unsuccessful and must include pre-operative warnings of sharp pain. However it may prove useful for pulpal extirpation or endodontic treatment on any tooth where anaesthesia is difficult to achieve. Nevertheless, due to the patient discomfort associated with this technique it should not be the primary anaesthetic technique used.

Intra-papillary

Intra-papillary anaesthesia is used as a supplementary technique to infiltrations in order to increase comfort for the patient and is primarily used to replace palatal or lingual infiltrations. This is exceptionally successful in paediatric patients and works to replace or increase comfort for particularly uncomfortable infiltrations such as palatal or lingual infiltrations. The technique involves direct deposition of anaesthetic agent into the papilla with associated tissue blanching at site of injection. The point of penetration should lie in attached gingiva 2mm apical of the papilla [13]

Pressure anesthesia

Pressure with a cotton swab in the area to distract the nerve sensation of pain when the needle enters certain areas such as palatal tissue. [14]

Akinoski approach

Electrical nerve blocks

Technology that involves using electric current to block the reception or generation of pain signals; the pain control can be transient.

Jet injection

A jet injection aims to create a release of pressure strong enough to push a liquid medication dose through a small orifice. This is usually done with the help of an energy source which is mechanical. With this, a thin column of fluid is created which has the force to penetrate soft tissues, thus a needle is not required. [15]

Advantages:

However, in dentistry, the effectiveness of this technique has been reported to be limited. [15]

Examples of jet injections include: Syrijet, MED-JET H III and iCT injection SE by Dentium. [16]

Dosage

References: [17] [18] [19] [20]

Drug
name
UK
Trade name
Concentration
(%)
Maximum dose
(mg/kg)
Articaine with adrenalineBartinest

Septanest

47
BupivacaineMarcain0.252.5
Lidocaine13
2
Lidocaine with adrenalineUtilycaine

Lignospan Special

Xylocaine

17
2
MepivacaineScandonest21.36 (3 mg per pound), less than 400 mg in adults
3
Prilocaine with FelypressinCitanest0.57
1
Prilocaine PlainCitanest Plain16

Contraindications

When considering the use of a local anaesthesia there are many factors which should be considered. In terms of contraindications associated with LA there are "absolute" and "relative" contraindications. When something is said to have an "absolute" contraindication this underlines that under no circumstance would that LA be selected to administer to that specific patient as it poses a potential life-threatening risk e.g. allergy. When the LA has a "relative" contraindication the administration of the LA is not preferable and should be avoided, but does not pose a life-threatening risk.

Type

As stated previously, local anaesthesia used in dentistry can vary significantly as there are various preparations with a multitude of qualities. Each preparation has slight differences in how the anaesthetic affects the body. This is due to the use of different constituents. Local Anaesthetics which contain adrenaline such as Lidocaine (using 1:80,000 of adrenaline) or Articaine (using 1:100,000 of adrenaline) have a direct effect on the cardiac output by increasing the rate and contraction of the heart itself. Due to these effects, if a patient has unstable angina or severe cardiac dysrhythmia, these preparations are often discouraged as they may predispose to unfavourable side effects. [21] Studies found that both articaine given by infiltration and lidocaine given by inferior block were equally efficient when used for routine dental treatments in pediatric patients, however, articaine injections caused less post-operative pain. [22]

As an alternative, other preparations such as Mepivicaine Hydrochloride or Prilocaine (containing Felypressin) can be used. Prilocaine is especially suitable for a patient who wishes to avoid adrenaline or may have a latex/preservative allergy. The main contraindication of Prilocaine is that it has a short half life and it possesses a mild cytotoxic effect, therefore should be avoided in pregnancy. This cytotoxic effect can influence the uterine tone and interfere with circulation, which can pose detrimental effects on the pregnancy. Mepivicaine Hydrochloride is then considered if Prilocaine is contraindicated. Mepivicaine is the least vasodilatory anesthetic as it has no vasoconstrictors and no preservatives added. [23]

In relation to the dose

The dose of local anesthesia is often reduced when a patient has any systemic health implications or habits which may cause an interference. From time to time the local anaesthetic itself should be reduced (therefore reducing the maximum dose). This is particularly done when alcoholism, anaemia (if using Prilocaine), anorexia, bradycardia, or GORD (Gastroesophageal reflux disease) is concerned. On other occasions the vasoconstrictor used (often adrenaline) must be reduced when an individual has angina, bradycardia, chronic bronchitis, cardiac arrhythmia, COPD (Chronic Obstructive Pulmonary Disease), or glaucoma. Other issues include drug abuse, calcium channel blocker containing medications, beta blocker medications, or liver disease as these impair metabolism of the anaesthetic.

In relation to the technique

The variety of techniques associated when giving a local anaesthetic can affect the success and if done incorrectly lead to a possible fracture of the needle tip. It is extremely rare for the needle to fracture whilst giving an injection intra-orally unless an inadequate technique is adopted. To prevent such an occurrence, especially when performing an inferior alveolar nerve block, it is recommended to not bend the needle, to use the correct needle length and to not insert the needle up to the hub.

Most common local anesthetic procedure

The Inferior alveolar nerve anaesthesia or block or IANB (sometimes termed "inferior dental block", or wrongly referred to as the "mandibular block") probably is anesthetized more often than any other nerve in the body. An injection blocks sensation in the inferior alveolar nerve, which runs from the angle of the mandible down the medial aspect of the mandible, innervating the mandibular teeth, lower lip, chin, and parts of the tongue, which is effective for dental work in the mandibular arch. To anesthetize this nerve, the needle is inserted somewhat posterior to the most distal mandibular molar on one side of the mouth. The lingual nerve is also anesthetized through diffusion of the agent to produce a numb tongue as well as anesthetizing the floor of the mouth tissue, including that around the tongue side or lingual of the teeth. [24]

Several nondental nerves are usually anesthetized during an inferior alveolar block. The mental nerve, which supplies cutaneous innervation to the anterior lip and chin, is a distal branch of the inferior alveolar nerve. When the inferior alveolar nerve is blocked, the mental nerve is blocked also, resulting in a numb lip and chin. Nerves lying near the point where the inferior alveolar nerve enters the mandible often are also anesthetized during inferior alveolar anesthesia, such as affecting hearing (auriculotemporal nerve). [24]

The facial nerve lies some distance from the inferior alveolar nerve within the parotid salivary gland, but in rare cases anesthetic can be injected far enough posteriorly to anesthetize that nerve. The result is a transient facial paralysis, with the injected side of the face having temporary loss of the use of the muscles of facial expression that include the inability to close the eyelid and the drooping of the labial commissure on the affected side for a few hours, which disappears when the anesthesia wears off. [14]

In contrast, the superior alveolar nerves are not usually anesthetized directly because they are difficult to approach with a needle. For this reason, the maxillary arch is usually anesthetized locally for dental work by inserting the needle beneath the oral mucosa surrounding the teeth so as to anesthetize the smaller branches. [24]

Dental syringe

A dental syringe is a syringe for the injection of a local anesthetic. [25] It consists of a breech-loading syringe fitted with a sealed cartridge containing an anesthetic solution.

In 1928, Bayer Dental developed, coined and produced a sealed cartridge system under the registered trademark Carpule®. The current trademark owner is Kulzer Dental GmbH.

The carpules have long been reserved for anesthetic products for dental use. It is practically a bottomless flask. The latter is replaced by an elastomer plug that can slide in the body of the cartridge. This plug will be pushed by the plunger of the syringe. The neck is closed with a rubber cap. The dentist places the cartridge directly into a stainless steel syringe, with a double-pointed (single-use) needle. The tip placed on the cartridge side punctures the capsule and the piston will push the product. There is therefore no contact between the product and the ambient air during use.

In the UK and Ireland, manually operated hand syringes are used to inject lidocaine in to a patient's gums. [26] [27] [25]

Other anesthetics used in dentistry

Topical anaesthesia can also be used to reduce dental phobia, especially in children, by reducing discomfort and pain.

Drugs used in combination with general anesthesia

Local anesthesia and the pregnant patient

Provided a dentist performs proper aspiration to avoid intravenous injections, local anesthetics containing epinephrine (adrenaline) are safe to use during pregnancy. lignocaine and prilocaine are assigned a category B ranking by the FDA and are therefore safe for use during pregnancy. Lignocaine and prilocaine are sold as 2% and 4% formulations, respectively. It is therefore safer to use the lignocaine so as to administer a lower concentration of the drug to the pregnant patient. [28]

Mepivicaine, articaine, bupivicaine are given an FDA category C ranking and so should be avoided. Benzocaine, the ingredient of most topical anesthetic formulations, is also ranked as category C and should be avoided. Lignocaine should be used as topical anesthetic instead. [28]

Epinephrine in high doses is harmful to a pregnant woman in that it affects uterine blood flow. However its use in low dose with local anesthetic administration is warranted. The epinephrine causes vasoconstriction which in turn reduces systemic distribution of the anesthetic as well as prolongs its action in addition to decreasing bleeding at the operating site. Lidocaine 2% with 1:100,000 adrenaline is the local anesthetic of choice in the treatment of pregnant women. [28]

Allergy to local anaesthetic

Allergic reactions from local anaesthesia have been reported in some patients. However, this occurrence is rare even in patients who had a history of adverse reactions to LA.

There are mainly 2 classes of local anaesthetic agents: Amide or Ester linkages, based on their chemical structure. [29]

Genuine allergic reactions of an amide LA is very uncommon. An ester LA is more possible to result in an allergic reaction because the compound will be broken down to para-aminobenzoic acid (PABA) which is a trigger for allergic reactions. [30] In general dentistry, only topical applications of LA contains esters (benzocaine) when applied onto area before LA is administered.

If one is allergic to an ester LA, then the use of other types of ester LA should be avoided as the breakdown of all esters will produce PABA. However, patients allergic to ester LA will usually not be affected by amide LA because PABA is not produced upon breakdown of amide LA. Unlike ester LA, allergy to an amide LA will not eliminate the use of other types of amide LA. [30]

Some reactions are caused by administration of too much drug, usually because of the route of entry of drug (intravenously) or the quick uptake of drug into the system, or the aftereffect of the vasoconstrictor. [31] Unfavourable reactions to LA can be classified into 3 different groups: psychogenic, allergic, toxic.

Differential Diagnosis & management

Unfavourable reactions to LA are commonly due to a hyperemotional response to a perceived danger within someone's mind, and it could be demonstrated in several ways. Examples are temporal loss of consciousness, sweating, flush, change in heart rate or blood pressure, panic attack, hyperventilation, of which may be mistaken as allergic reactions. When treating such patients, treat them with care and take into consideration their anxiety. During treatment if the patients feel faint or experiences a drop in blood pressure, lay them flat and keep their legs elevated in an attempt to restore their blood pressure. Loosen any tight clothing and keep the patients sugary food/drink after they regain consciousness. Reassure the patient. [30]

It is important to ensure that children and adolescents experience less anxiety and fear to aid acceptance of future dental treatment. A study compared different methods to increase the acceptance of delivery of local anaesthetics to patients aged between 2–16 years old. These methods included the use of; audiovisual distraction (using 3D video glasses), a "wand" (computerised injection device), practising hypnosis, electrical counter-stimulation (a form of distraction) and video modelling. However, the evidence was insufficient to support their use. [32]

This may occur when there are large amounts of anaesthetic within their vascular system, which may owe to their receiving repeated LA, intravenous entry of drug or have underlying systemic conditions that do not metabolize or utilize the drug efficiently. [30] Signs and symptoms mainly involve the nervous system e.g. aggressive behaviour, drowsiness, speech alteration, disorientation etc.

Symptoms should usually resolve in a few hours, up to 12 hours, as the body will gradually rid the bloodstream of the drug. Assure the patient that their symptoms will improve after a few hours and that such a reaction should not recur and that there is no need to abstain from that drug hereafter.

Such reactions can be minimized via practising safe injection methods using an aspirating syringe to prevent injecting in blood vessels, slow administration of drug, and avoid overprescribing LA, keeping in mind the patient's weight, age and medical history.

Signs & symptoms of allergic reactions to LA

Genuine allergy to LA will manifest either as Type 1 or Type 4 hypersensitivity. Signs and symptoms will vary depending on the type of allergy. Type 1 reactions have a rapid onset of symptoms which include swelling, redness, rashes, itchiness, chest tightness, breathing problems. A Type 4 reaction has a delayed onset of symptoms and is usually localized to the site of injection.

Management

If a genuine allergic reaction to LA should occur, the patient should be treated as an emergency for anaphylaxis, according to the guidelines in the respective areas. For the UK, the section on medical emergencies in dental practice in the "Prescribing in Dental Practice" part in the BNF should be referred to. The patient should be sent immediately to the hospital if their condition worsens. [30]

The individual should undergo further tests to certify their allergy to the LA or for other possible causes of the adverse reaction.

Gate Control Theory in Painless Anaesthesia

The gate control theory explains that pain can be reduced if the touch nerve fibres are stimulated due to non-harmful stimuli.

Advancements in techniques used to deliver local anaesthesia are very important. There are types of local anaesthesia that apply vibrations to the skin while the injection is being placed into the skin. This uses the gate control theory to minimise pain to the patient. The high frequency vibrations coming from the device which is attached to the syringe inhibit the pain sensations coming from the needle insertion. The nerve fibres that are stimulated are the Aβ fibres which respond to pressure or vibration. Meissner's corpuscles, located in deeper tissues and bone are also affected. This closes a 'neural gate' which decreases the patient's feeling of pain.

Methods used by dentist to reduce pain during anaesthesia by using the gate control theory are: Warming of the local anaesthetic cartridge, Stretching the oral mucosa, Gentle rubbing of the extra-oral skin. [33]

Potential side effects

Myotoxicity

Although complications of myotoxicity in dental anaesthesia are rare, myotoxic injuries are primarily mediated by disturbances in calcium homeostasis. The onset of a myotoxic episode can occur within a few hours to a few days after local anaesthetic (LA) administration. A greater concentration and longer exposure to LA have been found to have a positive correlation with myotoxic effects. It can take human muscles from 4 days to a year to recover from a myotoxic insult. Local anaesthetics used clinically can be ranked in increasing order of their risk of myotoxicity, this includes Lidocaine, Ropivacaine and Bupivacaine. [34]

Ocular complications

Dental anaesthesia can present with many complications such as occlusal complications. There are many forms of dental anaesthesia that can cause these issues for example an Inferior Dental Block (IDB). Most commonly, ocular complications will present on the same side of the face where the injection was given. Symptoms include double vision followed by partial or full weakness in the eye muscle. Many pathophysiological processes have been discussed as a cause of these complications, including intra-arterial injection and autonomic dysregulation. Furthermore, following an incident, the patient should be reassured, and the eye should be covered with gauze to protect the eye until the corneal (blinking) reflex has returned. These symptoms usually resolve on their own but in the occurrence of persistence or deterioration, appropriate referral to an ophthalmologist should be made. [35]

Issues can also arise with use of nitrous oxide in patients who have had pneumatic retinopexy (alone or in conjunction with a vitrectomy), commonly used to treat retinal detachments. In these procedures, a gas is injected into the vitreous cavity as a tamponade and to promote re-adhesion of the detached retina. The gas bubble causes diffusion of nitrogen out of the bloodstream and into the bubble causing it to expand. Nitrous oxide is 34 times more soluble than nitrogen and will cause an extreme expansion, raising the intraocular pressure to dangerous levels. Such high intraocular pressures cause ischemia of the central retinal artery, leading to irreversible vision loss. [36] [37]

See also

Related Research Articles

<span class="mw-page-title-main">Anesthesia</span> State of medically-controlled temporary loss of sensation or awareness

Anesthesia or anaesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia, paralysis, amnesia, and unconsciousness. An individual under the effects of anesthetic drugs is referred to as being anesthetized.

Local anesthesia is any technique to induce the absence of sensation in a specific part of the body, generally for the aim of inducing local analgesia, i.e. local insensitivity to pain, although other local senses may be affected as well. It allows patients to undergo surgical and dental procedures with reduced pain and distress. In many situations, such as cesarean section, it is safer and therefore superior to general anesthesia.

<span class="mw-page-title-main">Local anesthetic</span> Medications to reversibly block pain

A local anesthetic (LA) is a medication that causes absence of all sensation in a specific body part without loss of consciousness, providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes unconsciousness. Local anesthetics are most commonly used to eliminate pain during or after surgery. When it is used on specific nerve pathways, paralysis also can be induced.

<span class="mw-page-title-main">Lidocaine</span> Local anesthetic

Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia. When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours. Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area. It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding.

<span class="mw-page-title-main">General anaesthesia</span> Medically induced loss of consciousness

General anaesthesia (UK) or general anesthesia (US) is a method of medically inducing loss of consciousness that renders a patient unarousable even with painful stimuli. This effect is achieved by administering either intravenous or inhalational general anaesthetic medications, which often act in combination with an analgesic and neuromuscular blocking agent. Spontaneous ventilation is often inadequate during the procedure and intervention is often necessary to protect the airway. General anaesthesia is generally performed in an operating theater to allow surgical procedures that would otherwise be intolerably painful for a patient, or in an intensive care unit or emergency department to facilitate endotracheal intubation and mechanical ventilation in critically ill patients. Depending on the procedure, general anaesthesia may be optional or required. Regardless of whether a patient may prefer to be unconscious or not, certain pain stimuli could result in involuntary responses from the patient that may make an operation extremely difficult. Thus, for many procedures, general anaesthesia is required from a practical perspective.

<span class="mw-page-title-main">Spinal anaesthesia</span> Form of neuraxial regional anaesthesia

Spinal anaesthesia, also called spinal block, subarachnoid block, intradural block and intrathecal block, is a form of neuraxial regional anaesthesia involving the injection of a local anaesthetic or opioid into the subarachnoid space, generally through a fine needle, usually 9 cm (3.5 in) long. It is a safe and effective form of anesthesia usually performed by anesthesiologists that can be used as an alternative to general anesthesia commonly in surgeries involving the lower extremities and surgeries below the umbilicus. The local anesthetic with or without an opioid injected into the cerebrospinal fluid provides locoregional anaesthesia: true anaesthesia, motor, sensory and autonomic (sympathetic) blockade. Administering analgesics in the cerebrospinal fluid without a local anaesthetic produces locoregional analgesia: markedly reduced pain sensation, some autonomic blockade, but no sensory or motor block. Locoregional analgesia, due to mainly the absence of motor and sympathetic block may be preferred over locoregional anaesthesia in some postoperative care settings. The tip of the spinal needle has a point or small bevel. Recently, pencil point needles have been made available.

<span class="mw-page-title-main">Inferior alveolar nerve</span> Branch of the mandibular nerve

The inferior alveolar nerve (IAN) (also the inferior dental nerve) is a sensory branch of the mandibular nerve (CN V3) (which is itself the third branch of the trigeminal nerve (CN V)). The nerve provides sensory innervation to the lower/mandibular teeth and their corresponding gingiva as well as a small area of the face (via its mental nerve).

Infiltration analgesia is deposition of an analgesic drug close to the apex of a tooth so that it can diffuse to reach the nerve entering the apical foramina. It is the most routinely used in dental local treatment.

<span class="mw-page-title-main">Bupivacaine</span> Local anaesthetic drug

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease sensation in a specific small area. In nerve blocks, it is injected around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to increase the duration of its action. It typically begins working within 15 minutes and lasts for 2 to 8 hours.

<span class="mw-page-title-main">Nerve block</span> Deliberate inhibition of nerve impulses

Nerve block or regional nerve blockade is any deliberate interruption of signals traveling along a nerve, often for the purpose of pain relief. Local anesthetic nerve block is a short-term block, usually lasting hours or days, involving the injection of an anesthetic, a corticosteroid, and other agents onto or near a nerve. Neurolytic block, the deliberate temporary degeneration of nerve fibers through the application of chemicals, heat, or freezing, produces a block that may persist for weeks, months, or indefinitely. Neurectomy, the cutting through or removal of a nerve or a section of a nerve, usually produces a permanent block. Because neurectomy of a sensory nerve is often followed, months later, by the emergence of new, more intense pain, sensory nerve neurectomy is rarely performed.

<span class="mw-page-title-main">Articaine</span> Chemical compound

Articaine is a dental amide-type local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries. It is the only local anaesthetic to contain a thiophene ring, meaning it can be described as 'thiophenic'; this conveys lipid solubility.

<span class="mw-page-title-main">Lingual nerve</span> Human nerve relaying sense to the tongue

The lingual nerve carries sensory innervation from the anterior two-thirds of the tongue. It contains fibres from both the mandibular division of the trigeminal nerve (CN V3) and from the facial nerve (CN VII). The fibres from the trigeminal nerve are for touch, pain and temperature (general sensation), and the ones from the facial nerve are for taste (special sensation).

<span class="mw-page-title-main">Prilocaine</span> Local anesthetic of the amino amide type

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

<span class="mw-page-title-main">Chloroprocaine</span> Local anaesthetic drug

Chloroprocaine is a local anesthetic given by injection during surgical procedures and labor and delivery. Chloroprocaine vasodilates; this is in contrast to cocaine which vasoconstricts. Chloroprocaine is an ester anesthetic.

A retrobulbar block is a regional anesthetic nerve block in the retrobulbar space, which is the area located behind the globe of the eye. Injection of local anesthetic into this space constitutes the retrobulbar block. This injection provides akinesia of the extraocular muscles by blocking cranial nerves II, III, and VI, thereby preventing movement of the globe. Cranial nerve IV lies outside the muscle cone, and therefore is not affected by the local anesthesia. As a result, intorsion of the eye is still possible. It also provides sensory anesthesia of the conjunctiva, cornea and uvea by blocking the ciliary nerves. This block is most commonly employed for cataract surgery, but also provides anesthesia for other intraocular surgeries.

Inferior alveolar nerve block is a nerve block technique which induces anesthesia (numbness) in the areas of the mouth and face innervated by one of the inferior alveolar nerves which are paired on the left and right side. These areas are the skin and mucous membranes of the lower lip, the skin of the chin, the lower teeth and the labial gingiva of the anterior teeth, all unilaterally to the midline of the side on which the block is administered. However, depending on technique, the long buccal nerve may not be anesthetized by an IANB and therefore an area of buccal gingiva adjacent to the lower posterior teeth will retain normal sensation unless that nerve is anesthetized separately, via a (long) buccal nerve block. The inferior alveolar nerve is a branch of the mandibular nerve, the third division of the trigeminal nerve. This procedure attempts to anaesthetise the inferior alveolar nerve prior to it entering the mandibular foramen on the medial surface of the mandibular ramus.

The following outline is provided as an overview of and topical guide to anesthesia:

Ocular surgery may be performed under topical, local or general anesthesia. Local anaesthesia is more preferred because it is economical, easy to perform and the risk involved is less. Local anaesthesia has a rapid onset of action and provides a dilated pupil with low intraocular pressure.

<span class="mw-page-title-main">Pterygomandibular space</span>

The pterygomandibular space is a fascial space of the head and neck. It is a potential space in the head and is paired on each side. It is located between the lateral pterygoid muscle and the medial surface of the ramus of the mandible. The pterygomandibular space is one of the four compartments of the masticator space.

References

  1. 1 2 St George, Geoffrey; Morgan, Alyn; Meechan, John; Moles, David R.; Needleman, Ian; Ng, Yuan-Ling; Petrie, Aviva (2018-07-10). "Injectable local anaesthetic agents for dental anaesthesia". The Cochrane Database of Systematic Reviews. 7 (7): CD006487. doi:10.1002/14651858.CD006487.pub2. ISSN   1469-493X. PMC   6513572 . PMID   29990391.
  2. 1 2 Leonard J (22 May 2018). Carter A (ed.). "How long does numbness last after the dentist?". Medical News Today. Retrieved July 14, 2020.
  3. 1 2 3 4 Malamed SF (2019-06-03). Handbook of local anesthesia. Elsevier. ISBN   978-0-323-58207-0. OCLC   1110034740.
  4. Kattan S, Lee SM, Hersh EV, Karabucak B (March 2019). "Do buffered local anesthetics provide more successful anesthesia than nonbuffered solutions in patients with pulpally involved teeth requiring dental therapy?: A systematic review". Journal of the American Dental Association. 150 (3): 165–177. doi:10.1016/j.adaj.2018.11.007. PMID   30803488. S2CID   73491294.
  5. 1 2 3 Meechan JG, Wilson NF (2010). Practical dental local anaesthesia (2nd ed.). London: Quintessence Pub. Co. ISBN   978-1850972044. OCLC   642291828.
  6. Khalil H (2014). "A basic review on the inferior alveolar nerve block techniques". Anesthesia: Essays and Researches. 8 (1): 3–8. doi: 10.4103/0259-1162.128891 . PMC   4173572 . PMID   25886095.
  7. Drum M, Reader A, Beck M (July 2011). "Long buccal nerve block injection pain in patients with irreversible pulpitis". Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 112 (1): e51–e54. doi:10.1016/j.tripleo.2011.01.028. PMID   21458333.
  8. Foster W, Drum M, Reader A, Beck M (2007). "Anesthetic efficacy of buccal and lingual infiltrations of lidocaine following an inferior alveolar nerve block in mandibular posterior teeth". Anesthesia Progress. 54 (4): 163–169. doi:10.2344/0003-3006(2007)54[163:AEOBAL]2.0.CO;2. PMC   2213247 . PMID   18085837.
  9. Masselink BH (1910). "The advent of painless dentistry". Dental Cosmos. 52 (8): 868–872.
  10. Malamed SF (February 1982). "The periodontal ligament (PDL) injection: an alternative to inferior alveolar nerve block". Oral Surgery, Oral Medicine, and Oral Pathology. 53 (2): 117–121. doi:10.1016/0030-4220(82)90273-0. PMID   6949113.
  11. 1 2 "Supplemental injections" (PDF). College of Dental Medicine. Columbia University. 2007.
  12. Pradhan R, Kulkarni D, Shetty L (January 2017). "Evaluation of Efficacy of Intraligamentary Injection Technique for Extraction of Mandibular Teeth-A Prospective Study". Journal of Clinical and Diagnostic Research. 11 (1): ZC110–ZC113. doi:10.7860/JCDR/2017/22204.9302. PMC   5324483 . PMID   28274058.
  13. "Supplementary techniques". pocketdentistry.com. 2015-01-03.
  14. 1 2 Fehrenbach MJ, Herring SW, eds. (2012). Illustrated Anatomy of the Head and Neck (4th ed.). St. Louis, Mo.: Elsevier/Saunders. p. 216. ISBN   978-1-4377-2419-6.
  15. 1 2 Saxena P, Gupta SK, Newaskar V, Chandra A (January 2013). "Advances in dental local anesthesia techniques and devices: An update". National Journal of Maxillofacial Surgery. 4 (1): 19–24. doi: 10.4103/0975-5950.117873 . PMC   3800379 . PMID   24163548.
  16. "Dentium | Product | New Product". www.dentium.com. Retrieved 2018-08-04.
  17. "Articaine / Epinephrine Dosage". Drugs.com. Retrieved 10 February 2018.
  18. Cadogan M. "Maximum Recommended Local Anaesthetic Doses for Adults". Life in the Fast Lane. Archived from the original on 21 May 2016. Retrieved 7 February 2018.
  19. "Maximum Recommended Local Anaesthetic Doses for Adults". Nottigham University Hospitals. March 2015. Archived from the original on 18 February 2018. Retrieved 10 February 2018.
  20. "Scandonest 3% Plain" . Retrieved 10 February 2018.
  21. Baart JA, Brand HS (2017-06-07). Local Anaesthesia in Dentistry. Springer. ISBN   9783319437057.
  22. Tong HJ, Alzahrani FS, Sim YF, Tahmassebi JF, Duggal M (July 2018). "Anaesthetic efficacy of articaine versus lidocaine in children's dentistry: a systematic review and meta-analysis" (PDF). International Journal of Paediatric Dentistry. 28 (4): 347–360. doi:10.1111/ipd.12363. PMID   29635712. S2CID   4799330.
  23. Millett D, Day P (2016-10-18). Clinical Problem Solving in Orthodontics and Paediatric Dentistry E-Book. Elsevier Health Sciences. ISBN   9780702064913.
  24. 1 2 3 Logothetis DD (2012). Local Anesthesia for the Dental Hygienist. St. Louis, Mo.: Elsevier/Mosby. ISBN   978-0-323-07371-4.[ page needed ]
  25. 1 2 "Lidocaine (Local) Monograph for Professionals". Drugs.com.
  26. Zakrzewska JM, Boon EC (August 2003). "Use of safety dental syringes in British and Irish dental schools". British Dental Journal. 195 (4): 207–9, discussion 198. doi: 10.1038/sj.bdj.4810445 . PMID   12970703.
  27. Zakrzewska JM, Greenwood I, Jackson J (January 2001). "Introducing safety syringes into a UK dental school--a controlled study". British Dental Journal. 190 (2): 88–92. doi: 10.1038/sj.bdj.4800891 . PMID   11213339.
  28. 1 2 3 Ouanounou A, Haas DA (April 2016). "Drug therapy during pregnancy: implications for dental practice". British Dental Journal. 220 (8): 413–417. doi:10.1038/sj.bdj.2016.299. PMID   27103292. S2CID   23691595.
  29. Saygin D, Tabib T, Bittar HE, Valenzi E, Sembrat J, Chan SY, et al. (2002). "Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension". Pulmonary Circulation. 10 (1): 26–39. doi:10.1034/j.1601-1546.2002.10103.x. PMC   7052475 . PMID   32166015.
  30. 1 2 3 4 5 Henderson S (2011). "Allergy to local anaesthetic agents used in dentistry--what are the signs, symptoms, alternative diagnoses and management options?". Dental Update. 38 (6): 410–412. doi:10.12968/denu.2011.38.6.410. PMID   21905354.
  31. Tomoyasu Y, Mukae K, Suda M, Hayashi T, Ishii M, Sakaguchi M, et al. (2011). "Allergic reactions to local anesthetics in dental patients: analysis of intracutaneous and challenge tests". The Open Dentistry Journal. 5: 146–149. doi: 10.2174/1874210601105010146 . PMC   3170934 . PMID   21915228.
  32. Monteiro J, Tanday A, Ashley PF, Parekh S, Alamri H (February 2020). "Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental treatment". The Cochrane Database of Systematic Reviews. 2020 (2): CD011024. doi:10.1002/14651858.cd011024.pub2. PMC   7045283 . PMID   32104910.
  33. Malik A (2015). "Technique tips--distraction anaesthesia: applying the gate control theory in delivering painless anaesthesia". Dental Update. 42 (1): 97. doi:10.12968/denu.2015.42.1.97. PMID   26062285.
  34. Hussain N, McCartney CJ, Neal JM, Chippor J, Banfield L, Abdallah FW (October 2018). "Local anaesthetic-induced myotoxicity in regional anaesthesia: a systematic review and empirical analysis". British Journal of Anaesthesia. 121 (4): 822–841. doi: 10.1016/j.bja.2018.05.076 . PMID   30236244. S2CID   52308049.
  35. Steenen SA, Dubois L, de Lange J (March 2017). "[Ocular complications of local anaesthesia in dentistry]". Nederlands Tijdschrift voor Tandheelkunde. 124 (3): 149–153. doi:10.5177/ntvt.2017.03.16186. PMID   28272587.
  36. Lockwood, A. J.; Yang, Y. F. (March 2008). "Nitrous oxide inhalation anaesthesia in the presence of intraocular gas can cause irreversible blindness". British Dental Journal . 204 (5): 247–248. doi: 10.1038/bdj.2008.158 . PMID   18327188.
  37. "Dental Clinic". www.vindentist.vn. Retrieved 2018-08-04.