galactinol-raffinose galactosyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.1.67 | ||||||||
CAS no. | 37277-70-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a galactinol-raffinose galactosyltransferase (EC 2.4.1.67) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are α-D-galactosyl-(1→3)-1D-myo-inositol and raffinose, whereas its two products are myo-inositol and stachyose.
This enzyme participates in galactose metabolism.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha-D-galactosyl-(1→3)-myo-inositol:raffinose galactosyltransferase. Other names in common use include galactinol-raffinose galactosyltransferase, and stachyose synthetase.
Raffinose is a trisaccharide composed of galactose, glucose, and fructose. It can be found in beans, cabbage, brussels sprouts, broccoli, asparagus, other vegetables, and whole grains. Raffinose can be hydrolyzed to D-galactose and sucrose by the enzyme α-galactosidase (α-GAL), an enzyme which in the lumen of the human digestive tract is only produced by bacteria in the large intestine. α-GAL also hydrolyzes other α-galactosides such as stachyose, verbascose, and galactinol, if present. The enzyme does not cleave β-linked galactose, as in lactose.
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