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Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease. When a sufficiently large percentage of a population has been vaccinated, herd immunity results. Herd immunity protects those who may be immunocompromised and cannot get a vaccine because even a weakened version would harm them. The effectiveness of vaccination has been widely studied and verified. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the elimination of diseases such as polio and tetanus from much of the world. However, some diseases, such as measles outbreaks in America, have seen rising cases due to relatively low vaccination rates in the 2010s – attributed, in part, to vaccine hesitancy. According to the World Health Organization, vaccination prevents 3.5–5 million deaths per year.
The MMR vaccine is a vaccine against measles, mumps, and rubella, abbreviated as MMR. The first dose is generally given to children around 9 months to 15 months of age, with a second dose at 15 months to 6 years of age, with at least four weeks between the doses. After two doses, 97% of people are protected against measles, 88% against mumps, and at least 97% against rubella. The vaccine is also recommended for those who do not have evidence of immunity, those with well-controlled HIV/AIDS, and within 72 hours of exposure to measles among those who are incompletely immunized. It is given by injection.
Thiomersal (INN), or thimerosal, also sold under the name merthiolate is an organomercury compound. It is a well-established antiseptic and antifungal agent.
The American Academy of Pediatrics (AAP) is the largest professional association of pediatricians in the United States. It is headquartered in Itasca, Illinois, and maintains an office in Washington, D.C. The AAP has published hundreds of policy statements, ranging from advocacy issues to practice recommendations.
Stanley Alan Plotkin is an American physician who works as a consultant to vaccine manufacturers, such as Sanofi Pasteur, as well as biotechnology firms, non-profits and governments. In the 1960s, he played a pivotal role in discovery of a vaccine against rubella virus while working at Wistar Institute in Philadelphia. Plotkin was a member of Wistar’s active research faculty from 1960 to 1991. Today, in addition to his emeritus appointment at Wistar, he is emeritus professor of Pediatrics at the University of Pennsylvania. His book, Vaccines, is the standard reference on the subject. He is an editor with Clinical and Vaccine Immunology, which is published by the American Society for Microbiology in Washington, D.C.
Vaccine hesitancy is a delay in acceptance, or refusal, of vaccines despite the availability of vaccine services and supporting evidence. The term covers refusals to vaccinate, delaying vaccines, accepting vaccines but remaining uncertain about their use, or using certain vaccines but not others. Although adverse effects associated with vaccines are occasionally observed, the scientific consensus that vaccines are generally safe and effective is overwhelming. Vaccine hesitancy often results in disease outbreaks and deaths from vaccine-preventable diseases. Therefore, the World Health Organization characterizes vaccine hesitancy as one of the top ten global health threats.
A vaccination schedule is a series of vaccinations, including the timing of all doses, which may be either recommended or compulsory, depending on the country of residence. A vaccine is an antigenic preparation used to produce active immunity to a disease, in order to prevent or reduce the effects of infection by any natural or "wild" pathogen. Vaccines go through multiple phases of trials to ensure safety and effectiveness.
The thiomersal vaccine controversy centers around public concerns and debates over the safety of thiomersal, a mercury-based preservative used in vaccines, with some fearing it could cause neurological disorders such as autism, despite extensive scientific research showing no credible evidence linking thiomersal to such conditions.
Neal A. Halsey is an American pediatrician, with sub-specialty training in infectious diseases, international health and epidemiology. Halsey is a professor emeritus of international health and director emeritus of the Institute for Vaccine Safety at the Johns Hopkins Bloomberg School of Public Health, in Baltimore, Maryland. He had a joint appointment in the Department of Pediatrics at the Johns Hopkins School of Medicine and serves as co-director of the Center for Disease Studies and Control in Guatemala.
A vaccination policy is a health policy adopted in order to prevent the spread of infectious disease. These policies are generally put into place by state or local governments, but may also be set by private facilities, such as workplaces or schools. Many policies have been developed and implemented since vaccines were first made widely available.
Hélène Mambu-ma-Disu is a Congolese public health expert, physician, pediatrician and United Nations diplomat. She served as a Regional Adviser for the African regional office of the United Nations' World Health Organization, and later went on to serve for 18 years as a World Health Organization Resident Representative in several countries in the region, before retiring in 2008. She is currently Senior Program Officer for the Sustainable Immunization Financing Program of the Sabin Vaccine Institute, for whom she coordinates field activities in Democratic Republic of the Congo, Republic of the Congo, and Madagascar.
Jean Marie Okwo-Bele is a Congolese physician, public health expert and former Director of the Department of Immunization, Vaccines and Biologicals of the World Health Organization (WHO).
NmVac4-A/C/Y/W-135 is the commercial name of the polysaccharide vaccine against the bacterium that causes meningococcal meningitis. The product, by JN-International Medical Corporation, is designed and formulated to be used in developing countries for protecting populations during meningitis disease epidemics.
The American College of Pediatricians (ACPeds) is a socially conservative advocacy group of pediatricians and other healthcare professionals in the United States, founded in 2002. The group advocates in favor of abstinence-only sex education and conversion therapy, and advocates against vaccine mandates, abortion rights and rights for LGBT people. As of 2022, its membership has been reported at about 700 physicians.
The Vaccines for Children Program (VFC) is a federally funded program in the United States providing no-cost vaccines to children who lack health insurance or who otherwise cannot afford the cost of the vaccination. The VFC program was created by the Omnibus Budget Reconciliation Act of 1993 and is required to be a new entitlement of each state's Medicaid plan under section 1928 of the Social Security Act. The program was officially implemented in October 1994 and serves eligible children in all U.S. states, as well as the Commonwealth of Puerto Rico, the U.S. Virgin Islands, American Samoa, Guam, and the Commonwealth of the Northern Mariana Islands.
Walter A. Orenstein served as the director of the United States' National Immunization Program, from May 1993 to January 2004.
Wendy Sue Swanson is an American pediatrician, educator and author, known for her Seattle Mama Doc blog.
California Senate Bill 277 (SB277) is a California law that removed personal belief as a reason for an exemption from the vaccination requirements for entry to private or public elementary or secondary schools in California, as well as day care centers. The final version of the bill was enacted by the California Legislature in 2015 and was signed into law by Governor Jerry Brown on June 30, 2015.
Vaccination policy of the United States is the subset of U.S. federal health policy that deals with immunization against infectious disease. It is decided at various levels of the government, including the individual states. This policy has been developed over the approximately two centuries since the invention of vaccination with the purpose of eradicating disease from the U.S. population, or creating a herd immunity. Policies intended to encourage vaccination impact numerous areas of law, including regulation of vaccine safety, funding of vaccination programs, vaccine mandates, adverse event reporting requirements, and compensation for injuries asserted to be associated with vaccination.
Yvonne "Bonnie" Maldonado is an American physician, pediatrician, and Professor of Pediatrics and of Health Research and Policy at Stanford University, with a focus on Infectious Diseases. She founded Stanford's pediatric HIV Clinic and now serves as Stanford University School of Medicine's Senior Associate Dean of Faculty Development and Diversity.
References
- ↑ "Antivaccine Movement: History, Current Effects on Immunization". Healio.com. SLACK Inc. 28 July 2010. Retrieved 11 April 2013.
- ↑ "New Immunization Alliance Issues National Call To Action" (Press release). Chicago: American Academy of Pediatrics. 18 September 2008. Archived from the original on 27 September 2011. Retrieved 11 April 2013.
- ↑ Fiore, Kristina (September 19, 2008). "Immunization Alliance Seeks to Strengthen Public Confidence in Vaccines". MedPage Today. Retrieved January 14, 2020.
- ↑ "US Immunization Alliance call for action". The Pharma Letter. September 9, 2008. Retrieved January 14, 2020.