| Building | Image | Location | First built | Use | Notes |
|---|
| Log Cabin (Bellevue, Nebraska) | | Bellevue, Nebraska | ca. 1835 | Residence | Fur trapper's log cabin; Likely oldest building in the state |
| Florence Mill | | Omaha, Nebraska | ca. 1846 | Commercial | Oldest mill in the state; construction overseen by Brigham Young |
| Willow Creek Pony Express Station | | Cozad, Nebraska | ca. 1849 | Commercial | Pony Express station, was moved a small distance in 1938 |
| Didier Cabin | | Brownville, Nebraska | ca. 1854 | Residence | |
| Arbor Lodge | | Nebraska City, Nebraska | ca. 1855 | Residence | Built for the founder of Arbor Day, Julius Sterling Morton |
| Mayhew Cabin | | Nebraska City, Nebraska | ca. 1855 | Residence | One of the oldest houses in Nebraska City |
| Fontenelle Bank | | Bellevue, Nebraska | ca. 1856 | Commercial | Oldest bank building in the state |
| William Hamilton House | | Bellevue, Nebraska | ca. 1856 | Residence | |
| Bank of Florence | | Omaha, Nebraska | ca. 1857 | Commercial | Oldest building in Omaha |
| Frederick L. Gottschalk House | | Columbus, Nebraska | ca. 1857 | Residence | The cabin was relocated to the interior of the Platte County Historical Society Museum. |
| Taylor-Wessel-Bickel-Nelson House | | Nebraska City, Nebraska | ca. 1857 | Residence | One of the oldest houses in Nebraska City |
| Presbyterian Church | | Bellevue, Nebraska | ca. 1858 | Religious | |
| Russell, Majors, and Waddell Freighting Company Building | | Nebraska City, Nebraska | ca. 1858 | Commercial/ Residence | Built by the US Army and sold to the supply firm Russell, Majors, and Waddell |
| Russell, Majors, Waddell House | | Nebraska City, Nebraska | ca. 1858 | Residence | Built by Alexander Majors for Russell, Majors, and Waddell |
| Russell, Majors, Waddell-Stevenson House | | Nebraska City, Nebraska | ca. 1858 | Residence | Built by Alexander Majors for Russell, Majors, and Waddell |
| Brownville Methodist Church | | Brownville, Nebraska | ca. 1859 | Religious | Oldest brick church in Nebraska |
| Abbott Gates House | | Brownville, Nebraska | ca. 1859 | Residence | |
| Midway Stage Station | | Dawson County, Nebraska | ca. 1859 | Commercial/ Residence | |
| Stolley Homestead Site | | Grand Island, Nebraska | ca. 1859 | Residence | |
| 8621 North 31st Street | | Omaha, Nebraska | ca. 1859 | Residence | Oldest house in Omaha; built within earlier Mormon settlement of Cutler's Park (Florence, Omaha). [1] |
| Brown-Carson House | | Brownville, Nebraska | ca. 1860 | Residence | |
| Emmanuel Lutheran Church | | Dakota City, Nebraska | ca. 1860 | Religious | |
| George and Nancy Turner House | | Fremont, Nebraska | ca. 1860 | Residence | |
| St. Benedict's Catholic Church | | Nebraska City, Nebraska | ca. 1861 | Religious | Oldest brick Catholic church in the state |
| United Presbyterian Church | | Nebraska City, Nebraska | ca. 1861 | Religious | Originally a Presbyterian church then used by the Mormons |
| 608 1st Avenue | | Nebraska City, Nebraska | ca. 1861 | Residence | |
| McLaughlin-Parks House | | Brownville, Nebraska | ca. 1862 | Residence | |
| Beehive House | | Brownville, Nebraska | ca. 1863 | Residence | |
| Heinrich Giese House | | Grand Island, Nebraska | ca. 1863 | Residence | |
| Worthing-Baker House | | Brownville, Nebraska | ca. 1863 | Residence | |
| Bratton-Minick House | | Brownville, Nebraska | ca. 1864 | Residence | |
| Jesse C. Bickle House | | Crete, Nebraska | ca. 1864 | Residence | |
| J. H. Catron House | | Nebraska City, Nebraska | ca. 1865 | Residence | |
| John Henry Stork Log House | | Burt County, Nebraska | ca. 1865 | Residence | |
| Otoe County Courthouse | | Nebraska City, Nebraska | ca. 1865 | Government | Oldest public building in the state |
| John Sautter Farmhouse | | Papillion, Nebraska | ca. 1866 | Residence | |
| George Stevens House | | Brownville, Nebraska | ca. 1866 | Residence | |
| Heritage House Museum | | Weeping Water, Nebraska | ca. 1867 | Residence | The former parsonage of the Congregational Church of Weeping Water |
| Palmer-Epard House | | Gage County, Nebraska | ca. 1867 | Residence | |
| Zweibel Farmstead | | Sarpy County, Nebraska | ca. 1867 | Residence | |
| Anthony P. Cogswell House | | Brownville, Nebraska | ca. 1868 | Residence | |
| Furnas House | | Brownville, Nebraska | ca. 1868 | Residence | Home of Governor Robert Wilkinson Furnas |
| John W. Bennett House | | Nemaha County, Nebraska | ca. 1868 | Residence | Oldest example of the I-House in the state |
| Lone Tree Saloon | | Brownville, Nebraska | ca. 1868 | Commercial | |
| Michael Witt Fachwerkbau | | Saline County, Nebraska | ca. 1868 | Residence | |
| St. John's Lutheran Church | | Nemaha County, Nebraska | ca. 1868 | Religious | Oldest stone church in Nebraska |
| Elm Creek Fort | | Minden, Nebraska | ca. 1869 | Residence | |
| Jasper A. Ware House | | Nebraska City, Nebraska | ca. 1869 | Residence | House of the co-founder of the Midland Pacific Railway, Jasper Ware |
| John L. Colhapp House | | Brownville, Nebraska | ca. 1869 | Residence | |
| Samuel Bullock House | | Fremont, Nebraska | ca. 1869 | Residence | |
| Thomas P. Kennard House | | Lincoln, Nebraska | ca. 1869 | Residence | One of oldest houses in Lincoln, NE |
| Tipton House | | Brownville, Nebraska | ca. 1869 | Residence | |
| 122 South 6th Street | | Plattsmouth, Nebraska | ca. 1869 | Religious | |
| Christopher Anderson House | | Nebraska City, Nebraska | ca. 1870 | Residence | |
| Commanding Officers Quarters | | Sidney, Nebraska | ca. 1870 | Government/ Residence | |
| Congregational Church and Manse | | Santee, Nebraska | ca. 1870 | Religious | |
| Eli S. Wibley House | | Brownville, Nebraska | ca. 1870 | Residence | |
| Naomi Institute | | Rock Bluff, Nebraska | ca. 1870 | Education | |
| Cook house on Spade Ranch (Nebraska) | | Ellsworth, Nebraska | ca. 1877 | Ranch | One of the oldest and largest ranches in Nebraska; Cookhouse moved from Newman Ranch in 1888. |
| General Crook House | | Fort Omaha | ca. 1879 | Government | Home to Civil War/Indian Wars general |
|