Maltose phosphorylase

maltose phosphorylase
maltose phosphorylase dimer, Lactobacillus brevis
Identifiers
EC no.	2.4.1.8
CAS no.	9030-19-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a maltose phosphorylase (EC 2.4.1.8) is an enzyme that catalyzes the chemical reaction

maltose + phosphate ${\displaystyle \rightleftharpoons }$ D-glucose + beta-D-glucose 1-phosphate

Thus, the two substrates of this enzyme are maltose and phosphate, whereas its two products are D-glucose and beta-D-glucose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is maltose:phosphate 1-beta-D-glucosyltransferase. This enzyme participates in starch and sucrose metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1H54.

References

• Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 5, Academic Press, New York, 1961, p. 229-236.
• FITTING C, DOUDOROFF M (1952). "Phosphorolysis of maltose by enzyme preparations from Neisseria meningitidis". J. Biol. Chem. 199 (1): 153–63. doi: 10.1016/S0021-9258(18)44822-3 . PMID   12999827.
• Putman EW, Litt CF, Hassid WZ (1955). "The structure of D-glucose-D-xylose synthesized by maltose phosphorylase". J. Am. Chem. Soc. 77 (16): 4351–4353. doi:10.1021/ja01621a050.
• Wood BJ, Rainbow C (1961). "The maltophosphorylase of beer lactobacilli". Biochem. J. 78 (1): 204–209. doi:10.1042/bj0780204. PMC   1205197 . PMID   13786484.