| Nucleus reuniens | |
|---|---|
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| Details | |
| Identifiers | |
| Latin | nucleus reuniens |
| NeuroNames | 309 |
| NeuroLex ID | birnlex_770 |
| TA98 | A14.1.08.632 |
| FMA | 62153 |
| Anatomical terms of neuroanatomy | |
The nucleus reuniens is a region of the thalamic midline nuclear group. [1] [2] In the human brain, it is located in the interthalamic adhesion (massa intermedia). [3] [4] It is also known as the medioventral nucleus. [5]
The nucleus reuniens receives afferent input from a large number of structures, mainly from limbic and limbic-associated structures. [6] It sends projections to the medial prefrontal cortex, the hippocampus, perirhinal cortex, and entorhinal cortex, [7] [8] [9] although there exist sparse connections to many other afferent structures as well. [10]
The unique medial prefrontal cortex and hippocampal connectivity allows reuniens to regulate neural traffic in this cortical network related to changes in an organism's attentiveness, [11] making reuniens critical to associative learning, [12] memory retrieval, [13] memory generalization, [14] spatial route planning, [15] and resilience to stress. [16]
