The brainstem is the posterior part of the brain, continuous with the spinal cord. In the human brain the brainstem includes the midbrain, and the pons and medulla oblongata of the hindbrain. Sometimes the diencephalon, the caudal part of the forebrain, is included.
The glossopharyngeal nerve, known as the ninth cranial nerve, is a mixed nerve that carries afferent sensory and efferent motor information. It exits the brainstem out from the sides of the upper medulla, just rostral to the vagus nerve. The motor division of the glossopharyngeal nerve is derived from the basal plate of the embryonic medulla oblongata, while the sensory division originates from the cranial neural crest.
The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It carries information past the basal ganglia, separating the caudate nucleus and the thalamus from the putamen and the globus pallidus. The internal capsule contains both ascending and descending axons, going to and coming from the cerebral cortex. It also separates the caudate nucleus and the putamen in the dorsal striatum, a brain region involved in motor and reward pathways.
The spinothalamic tract is a sensory pathway from the skin to the thalamus. From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus.
The dorsal column–medial lemniscus pathway (DCML) is a sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (position) from the skin and joints. It transmits information from the body to the primary somatosensory cortex in the postcentral gyrus of the parietal lobe of the brain. The pathway receives information from sensory receptors throughout the body, and carries this in nerve tracts in the white matter of the dorsal columns of the spinal cord, to the medulla where it is continued in the medial lemniscus, on to the thalamus and relayed from there through the internal capsule and transmitted to the somatosensory cortex. The name dorsal-column medial lemniscus comes from the two structures that carry the sensory information: the dorsal columns of the spinal cord, and the medial lemniscus in the brainstem.
One of the dorsal column nuclei, the cuneate nucleus is a wedge-shaped nucleus in the closed part of the medulla oblongata, in the brainstem. It contains cells that give rise to the cuneate tubercle, visible on the posterior aspect of the medulla. It lies lateral to the gracile nucleus and medial to the spinal trigeminal nucleus in the medulla.
The dentate nucleus is a cluster of neurons, or nerve cells, in the central nervous system that has a dentate – tooth-like or serrated – edge. It is located within the deep white matter of each cerebellar hemisphere, and it is the largest single structure linking the cerebellum to the rest of the brain. It is the largest and most lateral, or farthest from the midline, of the four pairs of deep cerebellar nuclei, the others being the fastigial nucleus and the globose and emboliform nuclei which together are referred to as the interposed nucleus. The dentate nucleus is responsible for the planning, initiation and control of voluntary movements. The dorsal region of the dentate nucleus contains output channels involved in motor function, which is the movement of skeletal muscle, while the ventral region contains output channels involved in nonmotor function, such as conscious thought and visuospatial function.
The zona incerta is a horizontally elongated region of gray matter in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord.
The ventral spinothalamic fasciculus situated in the marginal part of the anterior funiculus and intermingled more or less with the vestibulo-spinal fasciculus, is derived from cells in the posterior column or intermediate gray matter of the opposite side. Aβ fibres carry sensory information pertaining to crude touch from the skin. After entering the spinal cord the first order neurons synapse, and the second order neurons decussate via the anterior commissure. These second order neurons ascend synapsing in the VPL of the thalamus. It should also be noted incoming first order neurons can ascend or descend via the Lissauer tract.
In neuroanatomy, the dorsal column nuclei are a pair of nuclei in the dorsal columns in the brainstem. The name refers collectively to the cuneate nucleus and gracile nucleus, which are present at the junction between the spinal cord and the medulla oblongata. Both nuclei contain second-order neurons of the dorsal column-medial lemniscus pathway, which carries fine touch and proprioceptive information from the body to the brain. Each nucleus has an associated nerve tract, the gracile fasciculus and the cuneate fasciculus.
The principal sensory nucleus is a group of second order neurons which have cell bodies in the caudal pons.
The trigeminal lemniscus, also called the trigeminothalamic tract, is a part of the brain that conveys tactile, pain, and temperature impulses from the skin of the face, the mucous membranes of the nasal and oral cavities, and the eye, as well as proprioceptive information from the facial and masticatory muscles.
The posterior trigeminothalamic tract is composed of second order neuronal axons. These fibers carry sensory information about discriminative touch and conscious proprioception in the oral cavity from the principal nucleus to the ventral posteromedial (VPM) nucleus of the thalamus.
The cerebellothalamic tract or the tractus cerebellothalamicus, is part of the superior cerebellar peduncle. It originates in the cerebellar nuclei, crosses completely in the decussation of the superior cerebellar peduncle, bypasses the red nucleus, and terminates in posterior division of ventral lateral nucleus of thalamus. The ventrolateral nucleus has different divisions and distinct connections, mostly with frontal and parietal lobes. The primary motor cortex and premotor cortex get information from the ventrolateral nucleus projections originating in the interposed nucleus and dentate nuclei. Other dentate nucleus projections via thalamic pathway transmit information to prefrontal cortex and posterior parietal cortex. The cerebellum sends thalamocortical projections and in addition may also send connections from the thalamus to association areas serving cognitive and affective functions.
Ventral nucleus may refer to:
