PIP4K2C

PIP4K2C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GK9
Identifiers
Aliases	PIP4K2C , PIP5K2C, phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
External IDs	OMIM: 617104; MGI: 2152214; HomoloGene: 23484; GeneCards: PIP4K2C; OMA:PIP4K2C - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.3 Start 57,591,174 bp [1] End 57,603,418 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 D3 Start 127,032,936 bp [2] End 127,047,454 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis secondary oocyte hair follicle renal medulla Region I of hippocampus proper pons nasal epithelium buccal mucosa cell nipple islet of Langerhans Top expressed in retinal pigment epithelium neural layer of retina primary motor cortex pyloric antrum human kidney prefrontal cortex epithelium of stomach submandibular gland parotid gland CA3 field More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity nucleotide binding kinase activity phosphatidylinositol phosphate kinase activity identical protein binding ATP binding 1-phosphatidylinositol-5-phosphate 4-kinase activity Cellular component cytoplasm cytosol membrane autophagosome extracellular exosome Biological process phosphatidylinositol metabolic process positive regulation of autophagosome assembly phosphorylation phosphatidylinositol phosphate biosynthetic process regulation of autophagy phosphatidylinositol biosynthetic process regulation of phosphatidylinositol 3-kinase signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79837 117150 Ensembl ENSG00000166908 ENSMUSG00000025417 UniProt Q8TBX8 Q91XU3 RefSeq (mRNA) NM_001146258 NM_001146259 NM_001146260 NM_024779 NM_054097 NM_001359280 RefSeq (protein) NP_001139730 NP_001139731 NP_001139732 NP_079055 NP_473438 NP_001346209 Location (UCSC) Chr 12: 57.59 – 57.6 Mb Chr 10: 127.03 – 127.05 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma is an enzyme in humans that is encoded by the PIP4K2C gene. ^[5] It is one of the phosphatidylinositol 4-phosphate 5-kinases.

References

1. GRCh38: Ensembl release 89: ENSG00000166908 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025417 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma".

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C)