This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase. Other names in common use include 5'-methylthioadenosine nucleosidase, 5'-deoxy-5'-methylthioadenosine phosphorylase, MTA phosphorylase, MeSAdo phosphorylase, MeSAdo/Ado phosphorylase, methylthioadenosine phosphorylase, methylthioadenosine nucleoside phosphorylase, 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase, and S-methyl-5-thioadenosine phosphorylase. This enzyme participates in methionine metabolism.
A salvage pathway is a pathway in which a biological product is produced from intermediates in the degradative pathway of its own or a similar substance. The term often refers to nucleotide salvage in particular, in which nucleotides are synthesized from intermediates in their degradative pathway.
Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase is an enzyme that in humans is encoded by the NP gene. It catalyzes the chemical reaction
ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein. It is a reversible post-translational modification that is involved in many cellular processes, including cell signaling, DNA repair, gene regulation and apoptosis. Improper ADP-ribosylation has been implicated in some forms of cancer. It is also the basis for the toxicity of bacterial compounds such as cholera toxin, diphtheria toxin, and others.
In enzymology, a S-methyl-5-thioribose-1-phosphate isomerase is an enzyme that catalyzes the chemical reaction
The enzyme methylthioribulose 1-phosphate dehydratase (EC .2.1.109) catalyzes the chemical reaction
In enzymology, a methylthioadenosine nucleosidase (EC 3.2.2.16) is an enzyme that catalyzes the chemical reaction
In enzymology, a NAD+ glycohydrolase (EC 3.2.2.5) is an enzyme that catalyzes the chemical reaction
In enzymology, a NAD(P)+-protein-arginine ADP-ribosyltransferase (EC 2.4.2.31) is an enzyme that catalyzes the chemical reaction using nicotinamide adenine dinucleotide
In enzymology, a deoxyuridine phosphorylase is an enzyme that catalyzes the chemical reaction
In enzymology, a nucleoside deoxyribosyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a pyrimidine-nucleoside phosphorylase is an enzyme that catalyzes the chemical reaction
Thymidine phosphorylase is an enzyme that is encoded by the TYMP gene and catalyzes the reaction:
In enzymology, an uridine phosphorylase is an enzyme that catalyzes the chemical reaction
In enzymology, a xanthine phosphoribosyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, an ATP adenylyltransferase (EC 2.7.7.53) is an enzyme that catalyzes the chemical reaction
In enzymology, a ribose-5-phosphate adenylyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a S-methyl-5-thioribose kinase is an enzyme that catalyzes the chemical reaction
S-methyl-5'-thioadenosine phosphorylase (MTAP) is an enzyme in humans responsible for polyamine metabolism. It is encoded by the methylthioadenosine phosphorylase (MTAP) gene on chromosome 9. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
Poly [ADP-ribose] polymerase 4 is an enzyme that in humans is encoded by the PARP4 gene.
S-methyl-5'-thioinosine phosphorylase is an enzyme with systematic name S-methyl-5'-thioinosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase. This enzyme catalyses the following chemical reaction
References
Gambacorta A, Zappia V (1979). "5'-Methylthioadenosine phosphorylase from Caldariella acidophila Purification and properties". Eur. J. Biochem. 101 (2): 317–24. doi:10.1111/j.1432-1033.1979.tb19723.x. PMID118001.
Garbers DL (1978). "Demonstration of 5'-methylthioadenosine phosphorylase activity in various rat tissues. Some properties of the enzyme from rat lung". Biochim. Biophys. Acta. 523 (1): 82–93. doi:10.1016/0005-2744(78)90011-6. PMID415762.
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