Thermitase

Thermitase
Identifiers
EC no.	3.4.21.66
CAS no.	69772-87-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Thermitase (EC 3.4.21.66, thermophilic Streptomyces serine proteinase, Thermoactinomyces vulgaris serine proteinase) is an enzyme. ^{[1] [2] [3] [4] [5]} This enzyme catalyses the following chemical reaction

Hydrolysis of proteins, including collagen

This peptidase is isolated from Thermoactinomyces vulgaris .

References

1. Mizusawa K, Yoshida F (November 1972). "Thermophilic Streptomyces alkaline proteinase. I. Isolation, crystallization, and physicochemical properties". The Journal of Biological Chemistry. 247 (21): 6978–84. doi: 10.1016/S0021-9258(19)44682-6 . PMID   5082135.
2. Borgia P, Campbell LL (December 1974). "Properties of two homologous alkaline proteases from Streptomyces rectus". Journal of Bacteriology. 120 (3): 1109–15. doi:10.1128/jb.120.3.1109-1115.1974. PMC   245889 . PMID   4373436.
3. Kleine R (1982). "Properties of thermitase, a thermostable serine protease from Thermoactinomyces vulgaris". Acta Biologica et Medica Germanica. 41 (1): 89–102. PMID   7051706.
4. Meloun B, Baudyš M, Kostka V, Hausdorf G, Frömmel C, Höhne WE (1985). "Complete primary structure of thermitase from Thermoactinomyces vulgaris and its structural features related to the subtilisin-type proteinases". FEBS Lett. 183 (2): 195–200. Bibcode:1985FEBSL.183..195M. doi: 10.1016/0014-5793(85)80775-4 .
5. Teplyakov AV, Kuranova IP, Harutyunyan EH, Vainshtein BK, Frömmel C, Höhne WE, Wilson KS (July 1990). "Crystal structure of thermitase at 1.4 A resolution". Journal of Molecular Biology. 214 (1): 261–79. doi: 10.1016/0022-2836(90)90160-n . PMID   2196375.

External links

• Thermitase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)