Alcohol use and sleep

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Alcohol (also known formally as ethanol), found in alcoholic beverages, can exacerbate sleep disturbances. During abstinence, sleep disruption is one of the greatest predictors of relapse. [1]

Contents

Moderate alcohol consumption and sleep disruptions

Moderate alcohol consumption 30–60 minutes before bedtime results in disruptions in sleep maintenance and sleep architecture that are mediated by blood alcohol levels. [2] Disruptions in sleep maintenance are most marked once alcohol has been completely metabolized from the body. Under conditions of moderate alcohol consumption where blood alcohol levels average 0.06–0.08% and decrease 0.01–0.02% per hour, an alcohol clearance rate of 4–5 hours would coincide with disruptions in sleep maintenance in the second half of an 8-hour sleep episode. [2] In terms of sleep architecture, moderate doses of alcohol facilitate "rebounds" in rapid eye movement (REM) and stage 1 sleep; following suppression in REM and stage 1 sleep in the first half of an 8-hour sleep episode, REM and stage 1 sleep increase well beyond baseline in the second half. Moderate doses of alcohol also increase slow wave sleep (SWS) in the first half of an 8-hour sleep episode. [2] Enhancements in REM sleep and SWS following moderate alcohol consumption are mediated by reductions in glutamatergic activity by adenosine in the central nervous system. [2] In addition, tolerance to changes in sleep maintenance and sleep architecture develops within 3 days of alcohol consumption before bedtime. [2]

Alcohol consumption and sleep improvements

Low doses of alcohol (one 360.0 ml (13 imp fl oz; 12 US fl oz) beer) are sleep-promoting by increasing total sleep time and reducing awakenings during the night. The sleep-promoting benefits of alcohol dissipate at moderate and higher doses of alcohol (two 12 oz. beers and three 12 oz. beers, respectively). [3] Previous experience with alcohol also determines whether or not alcohol is a "sleep promoter" or "sleep disrupter." Under free-choice conditions, in which subjects chose between drinking alcohol or water, inexperienced drinkers were sedated while experienced drinkers were stimulated following alcohol consumption. [4] In insomniacs, moderate doses of alcohol improve sleep maintenance. [5]

Alcohol consumption and fatigue

Sleepiness influences the severity of alcohol consumption. Conditions of sleep deprivation encourage more episodes of alcohol consumption. [2] Increased alcohol consumption during the winter months for Northern climate residents is attributed to escalations in fatigue. [6]

Alcohol abstinence and sleep disruptions

Sleep and hormonal disruptions following withdrawal from chronic alcohol consumption are the greatest predictors of relapse. [1] During abstinence, recovering alcoholics have attenuated melatonin secretion in the beginning of a sleep episode, resulting in prolonged sleep latencies. [7] Escalations in cortisol and core body temperatures during the sleep period contribute to poor sleep maintenance. [7] [8] Abstinent alcoholics tend to have lighter, more fragmented sleep than normal control subjects. Research indicates that it may take as long as one to two years for sleep to return to normal in abstinent alcoholics and that for some it may never return to normal.

See also

Related Research Articles

<span class="mw-page-title-main">Alcoholism</span> Problematic excessive alcohol consumption

Alcoholism is, broadly, any drinking of alcohol that results in significant mental or physical health problems. Because there is disagreement on the definition of the word alcoholism, it is not a recognized diagnostic entity. Predominant diagnostic classifications are alcohol use disorder (DSM-5) or alcohol dependence (ICD-11); these are defined in their respective sources.

<span class="mw-page-title-main">Alcoholic liver disease</span> Medical condition

Alcoholic liver disease (ALD), also called alcohol-related liver disease (ARLD), is a term that encompasses the liver manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosis or cirrhosis.

The long-term heavy consumption of alcohol can cause severe detrimental effects. Health effects associated with alcohol intake in large amounts include an increased risk of developing an alcohol use disorder, malnutrition, chronic pancreatitis, erectile dysfunction, heart failure, atrial fibrillation, gastritis, stomach ulcers, alcoholic liver disease, certain types of dementia, and several types of cancer. In addition, damage to the central nervous system and peripheral nervous system can occur from chronic heavy alcohol consumption. There is also an increased risk for accidental injuries, for example, those sustained in traffic accidents and falls. Studies show that individuals with heavy substance use have a much higher risk of having other disorders. A cross-sectional observational study found evidence that people who used substances had the highest risk for five of the disorders studied. However, even light and moderate alcohol consumption increase the risk for developing certain types of cancer. Among women, light drinkers have a four percent increase risk of breast cancer, while moderate drinkers have a 23 percent increase in risk of the disease.

<span class="mw-page-title-main">Drinking culture</span> Aspect of human behavior

Drinking culture is the set of traditions and social behaviors that surround the consumption of alcoholic beverages as a recreational drug and social lubricant. Although alcoholic beverages and social attitudes toward drinking vary around the world, nearly every civilization has independently discovered the processes of brewing beer, fermenting wine and distilling spirits.

<span class="mw-page-title-main">Alcohol dependence</span> Medical condition

Alcohol dependence is a previous psychiatric diagnosis in which an individual is physically or psychologically dependent upon alcohol.

<span class="mw-page-title-main">Alcohol and cardiovascular disease</span> Effects of alcohol consumption on cardiovascular health

Excessive alcohol intake is associated with an elevated risk of alcoholic liver disease (ALD), heart failure, some cancers, and accidental injury, and is a leading cause of preventable death in industrialized countries. Some studies have suggested that one drink per day may have cardiovascular benefits. However, these studies are controversial, and the common view is that no level of alcohol consumption improves health. There is far more evidence for the harmful effects of alcohol than for any beneficial effects. It is also recognized that the alcohol industry may promote the unsubstantiated benefits of moderate drinking.

Alcohol has a number of effects on health. Short-term effects of alcohol consumption include intoxication and dehydration. Long-term effects of alcohol include changes in the metabolism of the liver and brain, several types of cancer and alcohol use disorder. Alcohol intoxication affects the brain, causing slurred speech, clumsiness, and delayed reflexes. Alcohol consumption can cause hypoglycemia in diabetics on certain medications, such as insulin or sulfonylurea, by blocking gluconeogenesis. There is an increased risk of developing an alcohol use disorder for teenagers while their brain is still developing. Adolescents who drink have a higher probability of injury including death.

<span class="mw-page-title-main">Acamprosate</span> Medication

Acamprosate, sold under the brand name Campral, is a medication used along with counselling to treat alcohol use disorder.

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The modern disease theory of alcoholism states that problem drinking is sometimes caused by a disease of the brain, characterized by altered brain structure and function.

<span class="mw-page-title-main">Hangover</span> Effects following consumption of alcohol

A hangover is the experience of various unpleasant physiological and psychological effects usually following the consumption of alcohol, such as wine, beer, and liquor. Hangovers can last for several hours or for more than 24 hours. Typical symptoms of a hangover may include headache, drowsiness, concentration problems, dry mouth, dizziness, fatigue, gastrointestinal distress, absence of hunger, light sensitivity, depression, sweating, nausea, hyper-excitability, irritability, and anxiety.

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<span class="mw-page-title-main">Nightcap (drink)</span> Drink taken shortly before bedtime

A nightcap is a drink taken shortly before bedtime. For example, a small alcoholic drink or glass of warm milk can supposedly promote a good night's sleep.

<span class="mw-page-title-main">Short-term effects of alcohol consumption</span> Overview of the short-term effects of the consumption of alcoholic beverages

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Kindling due to substance withdrawal refers to the neurological condition which results from repeated withdrawal episodes from sedative–hypnotic drugs such as alcohol and benzodiazepines.

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While researchers have found that moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence, excessive alcohol consumption is associated with widespread and significant brain lesions. Other data – including investigated brain-scans of 36,678 UK Biobank participants – suggest that even "light" or "moderate" consumption of alcohol by itself harms the brain, such as by reducing brain grey matter volume. This may imply that alternatives and generally aiming for lowest possible consumption could usually be the advisable approach.

<span class="mw-page-title-main">Sleep deprivation in higher education</span> Health issue in students

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References

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