Alpha,alpha-trehalose synthase

Last updated
Alpha,alpha-trehalose synthase
Identifiers
EC no. 2.4.1.245
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Alpha,alpha-trehalose synthase (EC 2.4.1.245, trehalose synthase, trehalose synthetase, UDP-glucose:glucose 1-glucosyltransferase, TreT, PhGT) is an enzyme with systematic name ADP-glucose:D-glucose 1-alpha-D-glucosyltransferase. [1] [2] This enzyme catalyses the following chemical reaction

ADP-glucose + D-glucose alpha,alpha-trehalose + ADP

This enzyme requires Mg2+ for maximal activity.

Related Research Articles

<span class="mw-page-title-main">Trehalose</span> Chemical compound

Trehalose is a sugar consisting of two molecules of glucose. It is also known as mycose or tremalose. Some bacteria, fungi, plants and invertebrate animals synthesize it as a source of energy, and to survive freezing and lack of water.

<span class="mw-page-title-main">Glycogenin</span> Enzyme involved in converting glucose to glycogen

Glycogenin is an enzyme involved in converting glucose to glycogen. It acts as a primer, by polymerizing the first few glucose molecules, after which other enzymes take over. It is a homodimer of 37-kDa subunits and is classified as a glycosyltransferase.

<span class="mw-page-title-main">Glycogen debranching enzyme</span> Mammalian protein found in Homo sapiens

The glycogen debranching enzyme, in humans, is the protein encoded by the gene AGL. This enzyme is essential for the breakdown of glycogen, which serves as a store of glucose in the body. It has separate glucosyltransferase and glucosidase activities.

In enzymology, an isomaltulose synthase is an enzyme that catalyzes the chemical reaction

In enzymology, a maltose α-D-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha-1,4-glucan-protein synthase (ADP-forming) is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose-phosphate synthase (GDP-forming) is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose-phosphate synthase (UDP-forming) is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose phosphorylase is an enzyme that catalyzes the chemical reaction

In enzymology, an alpha,alpha-trehalose phosphorylase (configuration-retaining) is an enzyme that catalyzes the chemical reaction

In enzymology, a diglucosyl diacylglycerol synthase is an enzyme that catalyzes the chemical reaction

In enzymology, a glucosylglycerol-phosphate synthase is an enzyme that catalyzes the chemical reaction

In enzymology, a NDP-glucose—starch glucosyltransferase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Starch synthase</span> Enzyme family

In enzymology, a starch synthase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Sucrose-phosphate synthase</span> Class of enzymes

Sucrose-phosphate synthase (SPS) is a plant enzyme involved in sucrose biosynthesis. Specifically, this enzyme catalyzes the transfer of a hexosyl group from uridine diphosphate glucose (UDP-glucose) to D-fructose 6-phosphate to form UDP and D-sucrose-6-phosphate. This reversible step acts as the key regulatory control point in sucrose biosynthesis, and is an excellent example of various key enzyme regulation strategies such as allosteric control and reversible phosphorylation.

<span class="mw-page-title-main">Sucrose synthase</span> Protein family

In enzymology, a sucrose synthase is an enzyme that catalyzes the chemical reaction

In enzymology, a trehalose 6-phosphate phosphorylase is an enzyme that catalyzes the chemical reaction

Glucosyl-3-phosphoglycerate synthase is an enzyme with systematic name NDP-glucose:3-phospho-D-glycerate 2-alpha-D-glucosyltransferase. This enzyme catalyses the following chemical reaction

Glucosylglycerate synthase is an enzyme with systematic name ADP-glucose:D-glycerate 2-alpha-D-glucosyltransferase. This enzyme catalyses the following chemical reaction

(1→4)-α-D-Glucan 1-α-D-glucosylmutase is an enzyme with systematic name (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase. This enzyme catalyses the following chemical reaction

References

  1. Qu Q, Lee SJ, Boos W (November 2004). "TreT, a novel trehalose glycosyltransferring synthase of the hyperthermophilic archaeon Thermococcus litoralis". The Journal of Biological Chemistry. 279 (46): 47890–7. doi: 10.1074/jbc.m404955200 . PMID   15364950.
  2. Ryu SI, Park CS, Cha J, Woo EJ, Lee SB (April 2005). "A novel trehalose-synthesizing glycosyltransferase from Pyrococcus horikoshii: molecular cloning and characterization". Biochemical and Biophysical Research Communications. 329 (2): 429–36. doi:10.1016/j.bbrc.2005.01.149. PMID   15737605.