Donovan's solution

Last updated
Donovan's Solution
Names
IUPAC name
Iodomercury; triiodoarsane
Other names
Liquor hydriodatis arsenici et hydrargyri
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
RTECS number
  • CG3200000
UN number 1557
  • InChI=1S/AsI3.Hg.HI/c2-1(3)4;;/h;;1H/q;+1;/p-1
    Key: QLULWSBMTZWVDE-UHFFFAOYSA-M
  • [As](I)(I)I.I[Hg]
Properties
AsHgI4
Molar mass 783.12948
AppearanceClear, colourless, or pale yellow. Darkens with age.
Boiling point 403 °C (757 °F; 676 K) at 760 mmHg
Yes
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Toxic
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Donovan's solution is an inorganic compound prepared from arsenic triiodide and mercuric iodide. [1] Despite its name, it is a compound and not a solution.

Contents

Method

Donovan's solution can be prepared by mixing arsenic triiodide, mercuric iodide, and sodium bicarbonate in aqueous solution. [2] [3]

Cooley's cyclopædia of practical receipts and ... information on the arts, manufactures, and trades gives a more complex method. [4]

Uses

The solution has been used in veterinary medicine to treat chronic diseases of the skin [3] and as a folk remedy. [5] It was used during the 19th century to treat lepra vulgaris [6] and psoriasis [7] [8] in humans, taken internally.

References

  1. ↑ Budavari, Susan (1989). "3413. Donovan's Solution" . The Merck Index (11th ed.). Merck & Co., Inc. p.  537. ISBN   091191028X. LCCN   89060001.
  2. ↑ Navy Department. Bureau of Medicine and Surgery (1950). Pharmacy and Materia Medica: Military-medical Operations Courses. Bureau of Naval Personnel. p. 17.
  3. 1 2 Oxtoby, David W.; H.P. Gillis; Allan Campion (2012). Principles of modern chemistry (7th ed.). Belmont, Calif.: Brooks/Cole Cengage Learning. p. 513. ISBN   978-0840049315.
  4. ↑ Arnold James Cooley (1880). "Solution". In Richard Vine Tuson (ed.). A cyclopædia of practical receipts and ... information on the arts, manufactures, and trades. Vol. II (6th ed.). p. 1525.
  5. ↑ "Donovan's solution". Chemical Dictionary Online. Retrieved 29 November 2013.
  6. ↑ Sir Erasmus Wilson (1847). "Treatment of Lepra". On Diseases of the Skin (2nd ed.). John Churchill. p. 271.
  7. ↑ Henry G. Piffard (1881). "Psoriasis Treatment. Part 6". A Treatise On The Materia Medica And Therapeutics Of The Skin. Sampson, Low, Marston, Searle & Rivington. p. 254.
  8. ↑ "Good Results of Donovan's Solution in Psoriasis". The Lancet. 70 (1770): 116. August 1857. doi:10.1016/S0140-6736(02)38789-0.
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