Methyl-ONN-azoxymethanol beta-D-glucosyltransferase

Last updated
methyl-ONN-azoxymethanol beta-D-glucosyltransferase
Identifiers
EC no. 2.4.1.171
CAS no. 99283-65-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a methyl-ONN-azoxymethanol beta-D-glucosyltransferase (EC 2.4.1.171) is an enzyme that catalyzes the chemical reaction

UDP-glucose + methyl-ONN-azoxymethanol UDP + cycasin

Thus, the two substrates of this enzyme are UDP-glucose and methyl-ONN-azoxymethanol, whereas its two products are UDP and cycasin.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase. Other names in common use include cycasin synthase, uridine diphosphoglucose-methylazoxymethanol glucosyltransferase, and UDP-glucose-methylazoxymethanol glucosyltransferase.

Related Research Articles

In enzymology, a 13-hydroxydocosanoate 13-beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction. This reaction is part of sophorosyloxydocosanoate biosynthesis. Extracts for research are frequently obtained from Candida yeasts.

In enzymology, a 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an anthocyanidin 3-O-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a cis-p-Coumarate glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a cyanidin 3-O-rutinoside 5-O-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a cyanohydrin beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a dolichyl-phosphate beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a flavone 7-O-beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a gallate 1-beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a hydroxycinnamate 4-beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, an indole-3-acetate beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a phenol beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a poly(ribitol-phosphate) beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a pyridoxine 5'-O-beta-D-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a salicyl-alcohol beta-D-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a sterol 3beta-glucosyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a trans-zeatin O-beta-D-glucosyltransferase is an enzyme that catalyzes the chemical reaction

Zamia staggers is a fatal nervous disease affecting cattle in areas where they browse on the leaves or fruit of cycads—in particular, those of the genus Zamia. It is characterised by irreversible paralysis of the hind legs because of the degeneration of the spinal cord. It is caused by the toxins cycasin and macrozamin, β-glycosides of methylazoxymethanol (MAM), and which are found in all cycad genera.

<span class="mw-page-title-main">Cycasin</span> Chemical compound

Cycasin is a carcinogenic and neurotoxic glucoside found in cycads such as Cycas revoluta and Zamia pumila. Symptoms of poisoning include vomiting, diarrhea, weakness, seizures, and hepatotoxicity. In metabolic conditions, cycasin is hydrolyzed into glucose and methylazoxymethanol (MAM), the latter of which dissociates into formaldehyde and diazomethane.

References