Renal tissue kallikrein

Tissue kallikrein
Identifiers
EC no.	3.4.21.35
CAS no.	389069-73-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Renal tissue kallikrein (EC 3.4.21.35, glandular kallikrein, pancreatic kallikrein, submandibular kallikrein, submaxillary kallikrein, kidney kallikrein, urinary kallikrein, kallikrein , salivary kallikrein, kininogenin, kininogenase, callicrein, glumorin, padreatin, padutin, kallidinogenase, bradykininogenase, depot-padutin, urokallikrein, dilminal D, onokrein P) is an enzyme. ^{[1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [ excessive citations ]}

Renal tissue kallikrein is formed from kidney tissue prokallikrein by activation with the enzyme trypsin. It catalyses the chemical reaction causing preferential cleavage of Arg- bonds in small molecule substrates, acting to highly selectively release kallidin (lysyl-bradykinin, a bioactive kinin) from kininogen (a kinin protein precursor).

References

1. Fiedler F, Fink E, Tschesche H, Fritz H (1981). "Porcine glandular kallikreins". Proteolytic Enzymes, Part C. Methods in Enzymology. Vol. 80 Pt C. pp. 493–532. doi:10.1016/s0076-6879(81)80042-0. ISBN   978-0-12-181980-4. PMID   7043199.
2. Anundi H, Ronne H, Peterson PA, Rask L (December 1982). "Partial amino-acid sequence of the epidermal growth-factor-binding protein". European Journal of Biochemistry. 129 (2): 365–71. doi: 10.1111/j.1432-1033.1982.tb07059.x . PMID   6295764.
3. Pesquero JL, Boschcov P, Oliveira MC, Paiva AC (October 1982). "Effect of substrate size on tonin activity". Biochemical and Biophysical Research Communications. 108 (4): 1441–6. Bibcode:1982BBRC..108.1441P. doi:10.1016/s0006-291x(82)80068-5. PMID   6295383.
4. Gutkowska J, Corvol P, Figueiredo AF, Inagami T, Bouhnik J, Genest J (1984). "Kinetic studies of rat renin and tonin on purified rat angiotensinogen". Canadian Journal of Biochemistry and Cell Biology. 62 (2–3): 137–42. doi:10.1139/o84-020. PMID   6097352.
5. Kato H, Enjyoji K, Miyata T, Hayashi I, Oh-ishi S, Iwanaga S (February 1985). "Demonstration of arginyl-bradykinin moiety in rat HMW kininogen: direct evidence for liberation of bradykinin by rat glandular kallikreins". Biochemical and Biophysical Research Communications. 127 (1): 289–95. Bibcode:1985BBRC..127..289K. doi:10.1016/s0006-291x(85)80157-1. PMID   3844939.
6. Akiyama K, Nakamura T, Iwanaga S, Hara M (December 1987). "The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein". FEBS Letters. 225 (1–2): 168–72. Bibcode:1987FEBSL.225..168A. doi: 10.1016/0014-5793(87)81151-1 . PMID   3691800.
7. Evans BA, Drinkwater CC, Richards RI (June 1987). "Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus". The Journal of Biological Chemistry. 262 (17): 8027–34. doi: 10.1016/S0021-9258(18)47521-7 . PMID   3036794.
8. Fiedler F (March 1987). "Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin". European Journal of Biochemistry. 163 (2): 303–12. doi: 10.1111/j.1432-1033.1987.tb10801.x . PMID   3643848.
9. Fujinaga M, James MN (May 1987). "Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 A resolution". Journal of Molecular Biology. 195 (2): 373–96. doi:10.1016/0022-2836(87)90658-9. PMID   2821276.
10. Kato H, Nakanishi E, Enjyoji K, Hayashi I, Oh-ishi S, Iwanaga S (December 1987). "Characterization of serine proteinases isolated from rat submaxillary gland: with special reference to the degradation of rat kininogens by these enzymes". Journal of Biochemistry. 102 (6): 1389–404. doi:10.1093/oxfordjournals.jbchem.a122185. PMID   3482210.
11. Bailey GS (1989). "Rat pancreas kallikrein". Immunochemical Techniques Part M: Chemotaxis and Inflammation. Methods in Enzymology. Vol. 163. pp. 115–28. doi:10.1016/0076-6879(88)63013-8. ISBN   978-0-12-182064-0. PMID   3237072.
12. Blaber M, Isackson PJ, Marsters JC, Burnier JP, Bradshaw RA (September 1989). "Substrate specificities of growth factor associated kallikreins of the mouse submandibular gland". Biochemistry. 28 (19): 7813–9. doi:10.1021/bi00445a043. PMID   2611215.
13. Chao J, Chao L (1988). "Rat urinary kallikrein". Immunochemical Techniques Part M: Chemotaxis and Inflammation. Methods in Enzymology. Vol. 163. pp. 128–43. doi:10.1016/0076-6879(88)63014-x. ISBN   978-0-12-182064-0. PMID   3070295.
14. Geiger R, Miska W (1988). "[101 Human tissue kallikrein". Immunochemical Techniques Part M: Chemotaxis and Inflammation. Methods in Enzymology. Vol. 163. pp. 102–15. doi:10.1016/0076-6879(88)63012-6. ISBN   978-0-12-182064-0. PMID   3237071.
15. Bertrand R, Derancourt J, Kassab R (March 1989). "Selective cleavage at lysine of the 50 kDa-20 kDa connector loop segment of skeletal myosin S-1 by endoproteinase Arg-C". FEBS Letters. 246 (1–2): 171–6. Bibcode:1989FEBSL.246..171B. doi: 10.1016/0014-5793(89)80277-7 . PMID   2523317.
16. Wines DR, Brady JM, Pritchett DB, Roberts JL, MacDonald RJ (May 1989). "Organization and expression of the rat kallikrein gene family". The Journal of Biological Chemistry. 264 (13): 7653–62. doi: 10.1016/S0021-9258(18)83284-7 . PMID   2708383.
17. Elmoujahed A, Gutman N, Brillard M, Gauthier F (June 1990). "Substrate specificity of two kallikrein family gene products isolated from the rat submaxillary gland". FEBS Letters. 265 (1–2): 137–40. Bibcode:1990FEBSL.265..137E. doi: 10.1016/0014-5793(90)80903-v . PMID   2194829.
18. Xiong W, Chen LM, Chao J (February 1990). "Purification and characterization of a kallikrein-like T-kininogenase". The Journal of Biological Chemistry. 265 (5): 2822–7. doi: 10.1016/S0021-9258(19)39875-8 . PMID   2303430.

External links

• Tissue+kallikrein at the U.S. National Library of Medicine Medical Subject Headings (MeSH)