Streptogrisin A

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Streptogrisin A
Identifiers
EC no. 3.4.21.80
CAS no. 55326-50-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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NCBI proteins

Streptogrisin A (EC 3.4.21.80, Streptomyces griseus protease A, protease A, proteinase A, Streptomyces griseus proteinase A, Streptomyces griseus serine proteinase 3, Streptomyces griseus serine proteinase A) is an enzyme. [1] [2] [3] [4] [5] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with specificity similar to chymotrypsin

This enzyme is isolated from Streptomyces griseus .

References

  1. Johnson P, Smillie LB (May 1971). "The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus". Canadian Journal of Biochemistry. 49 (5): 548–62. doi:10.1139/o71-082. PMID   5575653.
  2. Sielecki AR, Hendrickson WA, Broughton CG, Delbaere LT, Brayer GD, James MN (November 1979). "Protein structure refinement: Streptomyces griseus serine protease A at 1.8 A resolution". Journal of Molecular Biology. 134 (4): 781–804. doi:10.1016/0022-2836(79)90486-8. PMID   119870.
  3. James MN, Sielecki AR, Brayer GD, Delbaere LT, Bauer CA (November 1980). "Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis". Journal of Molecular Biology. 144 (1): 43–88. doi:10.1016/0022-2836(80)90214-4. PMID   6783761.
  4. Delbaere LT, Brayer GD (May 1985). "The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates". Journal of Molecular Biology. 183 (1): 89–103. doi:10.1016/0022-2836(85)90283-9. PMID   3892018.
  5. Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT (August 1987). "Characterization and structure of genes for proteases A and B from Streptomyces griseus". Journal of Bacteriology. 169 (8): 3778–84. doi:10.1128/jb.169.8.3778-3784.1987. PMC   212465 . PMID   3112129.