Coprococcus | |
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Scientific classification | |
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Genus: | Coprococcus Holdeman and Moore 1974 [1] |
Type species | |
Coprococcus eutactus Holdeman and Moore 1974 | |
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Coprococcus is a genus of obligately anaerobic, nonmotile, Gram-positive cocci that are part of the human and animal gut microbiota. [2]
Coprococcus spp. are notable for their ability to ferment dietary fibers into short-chain fatty acids, especially butyrate, which is a key metabolite that supports colonocyte health, enhances mucosal integrity, and has anti-inflammatory properties. The genus is considered an important contributor to colonic homeostasis and overall gut health. [3]
Depletion of Coprococcus has been reported in patients with colorectal cancer, although a direct protective role remains to be fully established. [4]
One species, Coprococcus comes, may also influence the efficacy of blood pressure-lowering medications by modifying gut metabolism of esterified angiotensin-converting enzyme (ACE) inhibitors. [5]
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) [1] and the National Center for Biotechnology Information (NCBI) [6]
16S rRNA-based LTP_10_2024 [7] [8] [9] | 120 marker gene-based GTDB 09-RS220 [10] [11] [12] | ||||||||||||||||||||||||
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Additional species placed elsewhere in LTP and GTDB phylogenies:
From Ancient Greek:
→ Coprococcus – faecal coccus