Esuprone

Esuprone
Names
	Preferred IUPAC name 3,4-Dimethyl-2-oxo-2H-1-benzopyran-7-yl ethanesulfonate
Identifiers
CAS Number	91406-11-0 ;
3D model (JSmol)	Interactive image ;
ChEMBL	ChEMBL18504 ;
ChemSpider	59239 ;
PubChem CID	65827 ;
UNII	K7EB9E48ZE ;
CompTox Dashboard (EPA)	DTXSID60238549 ;
	InChI InChI=1S/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3 Key: CHDGAVDQRSPBTA-UHFFFAOYSA-N ; InChI=1/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3 Key: CHDGAVDQRSPBTA-UHFFFAOYAR;
	SMILES O=S(=O)(Oc2ccc\1c(OC(=O)/C(=C/1C)C)c2)CC;
Properties
Chemical formula	C13H14O5S
Molar mass	282.31 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Last updated December 31, 2025

Esuprone is an experimental drug candidate being investigated as an antidepressant.^[2] It acts as a monoamine oxidase A (MAO-A) inhibitor.^[3]

References

↑ Ganellin, C. R (1996). Dictionary of pharmacological agents. CRC Press. p. 1056. ISBN 978-0-412-46630-4.
↑ Vértes, Attila (2003). Handbook of nuclear chemistry. Springer. p. 155. ISBN 978-1-4020-1316-4.
↑ Bergström, M; Westerberg, G; Németh, G; Traut, M; Gross, G; Greger, G; Müller-Peltzer, H; Safer, A; et al. (1997). "MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: In vivo studies with positron emission tomography". European Journal of Clinical Pharmacology. 52 (2): 121–8. doi:10.1007/s002280050260. PMID 9174681. S2CID 25359613.

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[Ganellin-1] Ganellin, C. R (1996). Dictionary of pharmacological agents. CRC Press. p. 1056. ISBN 978-0-412-46630-4.

[Attila-2] Vértes, Attila (2003). Handbook of nuclear chemistry. Springer. p. 155. ISBN 978-1-4020-1316-4.

[3] Bergström, M; Westerberg, G; Németh, G; Traut, M; Gross, G; Greger, G; Müller-Peltzer, H; Safer, A; et al. (1997). "MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: In vivo studies with positron emission tomography". European Journal of Clinical Pharmacology. 52 (2): 121–8. doi:10.1007/s002280050260. PMID 9174681. S2CID 25359613.

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Names

Preferred IUPAC name 3,4-Dimethyl-2-oxo-2H-1-benzopyran-7-yl ethanesulfonate
Identifiers
CAS Number	91406-11-0 ^N
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL18504 ^Y
ChemSpider	59239 ^Y
PubChem CID	65827
UNII	K7EB9E48ZE ^Y
CompTox Dashboard (EPA)	DTXSID60238549
InChI InChI=1S/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3^Y Key: CHDGAVDQRSPBTA-UHFFFAOYSA-N^Y InChI=1/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3 Key: CHDGAVDQRSPBTA-UHFFFAOYAR
SMILES O=S(=O)(Oc2ccc\1c(OC(=O)/C(=C/1C)C)c2)CC
Properties^[1]
Chemical formula	C₁₃H₁₄O₅S
Molar mass	282.31 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references