Cimoxatone

Cimoxatone

Clinical data
ATC code	none
Identifiers
IUPAC name 3-[[4-[5-(methoxymethyl)-2-oxo-oxazolidin-3-yl]phenoxy]methyl]benzonitrile
CAS Number	73815-11-9  Y
PubChem CID	52542
ChemSpider	47493  Y
UNII	V6FT1QJ7VL
KEGG	D02581  Y
ChEMBL	ChEMBL2104092  N
CompTox Dashboard (EPA)	DTXSID50868273
ECHA InfoCard	100.070.537
Chemical and physical data
Formula	C19H18N2O4
Molar mass	338.363 g·mol−1
InChI InChI=1S/C19H18N2O4/c1-23-13-18-11-21(19(22)25-18)16-5-7-17(8-6-16)24-12-15-4-2-3-14(9-15)10-20/h2-9,18H,11-13H2,1H3 Y Key:MVVJINIUPYKZHR-UHFFFAOYSA-N Y
NY  (what is this?)    (verify)

Cimoxatone (MD 780515) is a reversible inhibitor of MAO-A (RIMA). ^[1] It was never marketed.

Cimoxatone has a half-life of 12.4 hours in humans. ^[2]

See also

• Monoamine oxidase inhibitor

References

1. Nair NP, Ahmed SK, Kin NM, West TE (1995). "Reversible and selective inhibitors of monoamine oxidase A in the treatment of depressed elderly patients". Acta Psychiatr Scand Suppl . 386: 28–35. doi:10.1111/j.1600-0447.1995.tb05921.x. PMID   7717092. S2CID   9100689.
2. "Cimoxatone: pharmacokinetics of various formulations" . InPharma. 427 (1): 6. 1984-03-01. doi:10.1007/BF03314342. ISSN   2230-6056.