Filtration is a physical separation process that separates solid matter and fluid from a mixture using a filter medium that has a complex structure through which only the fluid can pass. Solid particles that cannot pass through the filter medium are described as oversize and the fluid that passes through is called the filtrate. Oversize particles may form a filter cake on top of the filter and may also block the filter lattice, preventing the fluid phase from crossing the filter, known as blinding. The size of the largest particles that can successfully pass through a filter is called the effective pore size of that filter. The separation of solid and fluid is imperfect; solids will be contaminated with some fluid and filtrate will contain fine particles. Filtration occurs both in nature and in engineered systems; there are biological, geological, and industrial forms.
An Erlenmeyer flask, also known as a conical flask or a titration flask, is a type of laboratory flask which features a flat bottom, a conical body, and a cylindrical neck. It is most often used in a laboratory. It is named after the German chemist Emil Erlenmeyer (1825–1909), who created it in 1860.
Laboratory glassware refers to a variety of equipment used in scientific work, and traditionally made of glass. Glass can be blown, bent, cut, molded, and formed into many sizes and shapes, and is therefore common in chemistry, biology, and analytical laboratories. Many laboratories have training programs to demonstrate how glassware is used and to alert first–time users to the safety hazards involved with using glassware.
A magnetic stirrer or magnetic mixer is a laboratory device that employs a rotating magnetic field to cause a stir bar immersed in a liquid to spin very quickly, thus stirring it. The rotating field may be created either by a rotating magnet or a set of stationary electromagnets, placed beneath the vessel with the liquid. It is used in chemistry and biology as a convenient way to stir small volumes and where other forms of stirring, such as overhead stirrers and stirring rods, may not be viable.
A funnel is a tube or pipe that is wide at the top and narrow at the bottom, used for guiding liquid or powder into a small opening.
A Büchner funnel is a piece of laboratory equipment used in filtration. It is traditionally made of porcelain, but glass and plastic funnels are also available. On top of the funnel-shaped part there is a cylinder with a fritted glass disc/perforated plate separating it from the funnel. The Hirsch funnel has a similar design; it is used similarly, but for smaller quantities of material. The main difference is that the plate of a Hirsch funnel is much smaller, and the walls of the funnel angle outward instead of being vertical.
Organic synthesis is a branch of chemical synthesis concerned with the construction of organic compounds. Organic compounds are molecules consisting of combinations of covalently-linked hydrogen, carbon, oxygen, and nitrogen atoms. Within the general subject of organic synthesis, there are many different types of synthetic routes that can be completed including total synthesis, stereoselective synthesis, automated synthesis, and many more. Additionally, in understanding organic synthesis it is necessary to be familiar with the methodology, techniques, and applications of the subject.
Laboratory flasks are vessels or containers that fall into the category of laboratory equipment known as glassware. In laboratory and other scientific settings, they are usually referred to simply as flasks. Flasks come in a number of shapes and a wide range of sizes, but a common distinguishing aspect in their shapes is a wider vessel "body" and one narrower tubular sections at the top called necks which have an opening at the top. Laboratory flask sizes are specified by the volume they can hold, typically in metric units such as milliliters or liters. Laboratory flasks have traditionally been made of glass, but can also be made of plastic.
A separatory funnel, also known as a separation funnel, separating funnel, or colloquially sep funnel, is a piece of laboratory glassware used in liquid-liquid extractions to separate (partition) the components of a mixture into two immiscible solvent phases of different densities. Typically, one of the phases will be aqueous, and the other a lipophilic organic solvent such as ether, MTBE, dichloromethane, chloroform, or ethyl acetate. All of these solvents form a clear delineation between the two liquids. The more dense liquid, typically the aqueous phase unless the organic phase is halogenated, sinks to the bottom of the funnel and can be drained out through a valve away from the less dense liquid, which remains in the separatory funnel.
A Büchner flask, also known as a vacuum flask, filter flask, suction flask, side-arm flask, Kitasato flask or Bunsen flask, is a thick-walled Erlenmeyer flask with a short glass tube and hose barb protruding about an inch from its neck. The short tube and hose barb effectively act as an adapter over which the end of a thick-walled flexible hose (tubing) can be fitted to form a connection to the flask. The other end of the hose can be connected to source of vacuum such as an aspirator, vacuum pump, or house vacuum. Preferably this is done through a trap, which is designed to prevent the sucking back of water from the aspirator into the Büchner flask. The purpose of applying a vacuum is to speed the filtration by providing a pressure differential across the filter medium that is greater than that produced by gravity alone.
A dropping funnel is a type of laboratory glassware used to transfer liquids. They are fitted with a stopcock which allows the flow to be controlled. Dropping funnels are useful for adding reagents slowly, i.e. drop-wise. This may be desirable when the quick addition of the reagent results in side reactions, or if the reaction is too vigorous.
A stopcock is a form of valve used to control the flow of a liquid or gas. The term is not precise and is applied to many different types of valve. The only consistent attribute is that the valve is designed to completely stop the flow when closed fully.
Round-bottom flasks are types of flasks having spherical bottoms used as laboratory glassware, mostly for chemical or biochemical work. They are typically made of glass for chemical inertness; and in modern days, they are usually made of heat-resistant borosilicate glass. There is at least one tubular section known as the neck with an opening at the tip. Two- or three-necked flasks are common as well. Round bottom flasks come in many sizes, from 5 mL to 20 L, with the sizes usually inscribed on the glass. In pilot plants even larger flasks are encountered.
The Schlenk line is a commonly used chemistry apparatus developed by Wilhelm Schlenk. It consists of a dual manifold with several ports. One manifold is connected to a source of purified inert gas, while the other is connected to a vacuum pump. The inert-gas line is vented through an oil bubbler, while solvent vapors and gaseous reaction products are prevented from contaminating the vacuum pump by a liquid-nitrogen or dry-ice/acetone cold trap. Special stopcocks or Teflon taps allow vacuum or inert gas to be selected without the need for placing the sample on a separate line.
Agitated Nutsche filter (ANF) is a filtration technique used in applications such as dye, paint, and pharmaceutical production and waste water treatment. Safety requirements and environmental concerns due to solvent evaporation led to the development of this type of filter wherein filtration under vacuum or pressure can be carried out in closed vessels and solids can be discharged straightaway into a dryer.
Vacuum filtration is a fast filtration technique used to separate solids from liquids.
Cannula transfer or cannulation is a set of air-free techniques used with a Schlenk line, in transferring liquid or solution samples between reaction vessels via cannulae, avoiding atmospheric contamination. While the syringes are not the same as cannulae, the techniques remain relevant.
Fritted glass is finely porous glass through which gas or liquid may pass, made by sintering together glass particles into a solid but porous body. This porous glass body can also be called a frit. Applications in laboratory glassware include use in fritted glass filter items, scrubbers, or spargers. Other laboratory applications of fritted glass include packing in chromatography columns and resin beds for special chemical synthesis.
Laboratory drying rack is a pegboard for hanging and draining glassware in a laboratory. It is available in different varieties and sizes. It can be used for different materials of glassware in the laboratory room such as funnels, pipettes, mixing balls, slides, bottle stoppers, tubing and so on. In addition to that, the pegs on the drying rack are easily removable and replaceable in order to maintain the cleaning of the lab racks to avoid contamination with other apparatus used on the same rack. Any common laboratory needs to have at least two or three drying racks per lab.
Gravity filtration is a method of filtering impurities from solutions by using gravity to pull liquid through a filter. The two main kinds of filtration used in laboratories are gravity and vacuum/suction. Gravity filtration is often used in chemical laboratories to filter precipitates from precipitation reactions as well as drying agents, inadmissible side items, or remaining reactants. While it can also be used to separate out strong products, vacuum filtration is more commonly used for this purpose.
