Vial

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Vial of vaccine and syringe COVID-19 Vaccine vial and syringe - US Census.jpg
Vial of vaccine and syringe
Examples of modern flat-bottomed plastic vials Vial examples.jpg
Examples of modern flat-bottomed plastic vials
Sterile single-use vial of eye drops Ogondroppar2.jpg
Sterile single-use vial of eye drops

A vial (also known as a phial or flacon ) is a small glass or plastic vessel or bottle, often used to store medication in the form of liquids, powders, or capsules. They can also be used as scientific sample vessels; for instance, in autosampler devices in analytical chromatography. Vial-like glass containers date back to classical antiquity; modern vials are often made of plastics such as polypropylene. There are different types of vials such as a single dose vial and multi-dose vials often used for medications. The single dose vial is only used once whereas a multi-dose vial can be used more than once. The CDC sets specific guidelines on multi-dose vials.

Contents

History and etymology

A double-handled glass vial from Syria, c. 4th century AD Double-handled vial Louvre MND1503.jpg
A double-handled glass vial from Syria, c. 4th century AD

A vial can be tubular, or have a bottle-like shape with a neck. The volume defined by the neck is known as the headspace. The English word "vial" is derived from the Greek phiale, [2] meaning "a broad flat container". [3] Comparable terms include the Latin phiala, Late Latin fiola and Middle English fiole and viole.

Modern vials

Plastic hinge-top vials on a vial rack Hinge top vials on a vial rack.jpg
Plastic hinge-top vials on a vial rack

Modern vials are often made out of glass or plastic. They are often used as storage for small quantities of liquid used in medical or molecular biology applications. There are several different types of commonly used closure systems. For glass vials, options include screw vials (closed with a screw cap or dropper/pipette), lip vials (closed with a cork or plastic stopper) and crimp vials (closed with a rubber stopper and a metal cap). [4] Plastic vials, which can be moulded in plastic, can have other closure systems, such as 'hinge caps' which snap shut when pressed. These are sometimes called flip-tops or snap caps.

The bottom of a vial is often flat, unlike test tubes, which have usually a rounded bottom, but this is often not the case for small hinge-cap or snap-top vials. The small bottle-shaped vials typically used in laboratories are also known as bijou or McCartney's bottles. The bijou bottle tends to be smaller, often with a volume of around 10 milliliters.

See also

Related Research Articles

<span class="mw-page-title-main">Test tube</span> Glass or plastic laboratory glassware

A test tube, also known as a culture tube or sample tube, is a common piece of laboratory glassware consisting of a finger-like length of glass or clear plastic tubing, open at the top and closed at the bottom.

<span class="mw-page-title-main">Syringe</span> Medical injection device

A syringe is a simple reciprocating pump consisting of a plunger that fits tightly within a cylindrical tube called a barrel. The plunger can be linearly pulled and pushed along the inside of the tube, allowing the syringe to take in and expel liquid or gas through a discharge orifice at the front (open) end of the tube. The open end of the syringe may be fitted with a hypodermic needle, a nozzle or tubing to direct the flow into and out of the barrel. Syringes are frequently used in clinical medicine to administer injections, infuse intravenous therapy into the bloodstream, apply compounds such as glue or lubricant, and draw/measure liquids. There are also prefilled syringes.

<span class="mw-page-title-main">Bottle</span> Narrow-necked container

A bottle is a narrow-necked container made of an impermeable material in various shapes and sizes that stores and transports liquids. Its mouth, at the bottling line, can be sealed with an internal stopper, an external bottle cap, a closure, or induction sealing.

A screw cap or closure is a common type of closure for bottles, jars, and tubes.

<span class="mw-page-title-main">Bottle cap</span> Top for holding liquid inside a bottle

A bottle cap or bottle top is a closure for the top opening of a bottle. A cap is sometimes colorfully decorated with the logo of the brand of contents. Plastic caps are used for plastic bottles, while metal with plastic backing is used for glass; plastic caps are commonly made from polyethylene or polypropylene, while metal caps are usually either steel or aluminum. Plastic caps may have a pour spout. Flip-Top caps like Flapper closures provide controlled dispensing of dry products. Caps for plastic bottles are often made of a different type of plastic from the bottle.

<span class="mw-page-title-main">Jar</span> Rigid, approximately cylindrical container with a wide mouth or opening

A jar is a rigid, cylindrical or slightly conical container, typically made of glass, ceramic, or plastic, with a wide mouth or opening that can be closed with a lid, screw cap, lug cap, cork stopper, roll-on cap, crimp-on cap, press-on cap, plastic shrink, heat sealed lidding film, an inner seal, a tamper-evident band, or other suitable means. The English word "jar" originates from the Arabic word jarra, which means an earthen pot or vessel.

<span class="mw-page-title-main">Stopper (plug)</span> Conical closure used to seal a container

A stopper is a cylindrical or conical closure used to seal a container, such as a bottle, tube or barrel. Unlike a lid or bottle cap, which encloses a container from the outside without displacing the inner volume, a bung is partially or wholly inserted inside the container to act as a seal. Synonyms are bung and cork. A bung can be defined as "a plug or closure used to close an opening in a drum or barrel. It is called a plug when referring to a steel drum closure."

<span class="mw-page-title-main">Closure (container)</span> Devices and techniques used to close or seal a bottle, jug, jar, tube, can, etc.

A closure is a device used to close or seal a container such as a bottle, jug, jar, tube, or can. A closure may be a cap, cover, lid, plug, liner, or the like. The part of the container to which the closure is applied is called the finish.

<span class="mw-page-title-main">Ampoule</span> Small sealed vial

An ampoule is a small sealed vial which is used to contain and preserve a sample, usually a solid or liquid. Ampoules are usually made of glass.

Wine accessories are things that may be used in the storage or serving of wine. Wine accessories include many items such as wine glasses, corkscrews, and wine racks.

<span class="mw-page-title-main">Glass bottle</span> Narrow-necked container

A glass bottle is a bottle made from glass. Glass bottles can vary in size considerably, but are most commonly found in sizes ranging between about 200 millilitres and 1.5 litres. Common uses for glass bottles include food condiments, soda, liquor, cosmetics, pickling and preservatives; they are occasionally also notably used for the informal distribution of notes. These types of bottles are utilitarian and serve a purpose in commercial industries.

<span class="mw-page-title-main">Jug</span> Container used to hold liquid

A jug is a type of container commonly used to hold liquids. It has an opening, sometimes narrow, from which to pour or drink, and has a handle, and often a pouring lip. Jugs throughout history have been made of metal, ceramic, or glass, and plastic is now common.

<span class="mw-page-title-main">Induction sealing</span> Process of bonding thermoplastic materials by induction heating

Induction sealing is the process of bonding thermoplastic materials by induction heating. This involves controlled heating an electrically conducting object by electromagnetic induction, through heat generated in the object by eddy currents.

<span class="mw-page-title-main">Ground glass joint</span> Used in laboratories to easily assemble apparatus from parts

Ground glass joints are used in laboratories to quickly and easily fit leak-tight apparatus together from interchangeable commonly available parts. For example, a round bottom flask, Liebig condenser, and oil bubbler with ground glass joints may be rapidly fitted together to reflux a reaction mixture. This is a large improvement compared with older methods of custom-made glassware, which was time-consuming and expensive, or the use of less chemical resistant and heat resistant corks or rubber bungs and glass tubes as joints, which took time to prepare as well.

Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form.

<span class="mw-page-title-main">Canteen (bottle)</span> Reusable type of water bottle

A canteen is a reusable drinking water bottle designed to be used by hikers, campers, soldiers, bush firefighters, and workers in the field. It is usually fitted with a shoulder strap or means for fastening it to a belt, and may be covered with a cloth bag and padding to protect the bottle and insulate the contents. If the padding is soaked with water, evaporative cooling can help keep the contents of the bottle cool. Many canteens also include a nested canteen cup.

<span class="mw-page-title-main">Drug packaging</span> Packaging for pharmaceutical preparations

Pharmaceutical packaging is the packages and the packaging processes for pharmaceutical preparations. It involves all of the operations from production through drug distribution channels to the end consumer.

<span class="mw-page-title-main">Reagent bottle</span> Laboratory storage container

Reagent bottles, also known as media bottles or graduated bottles, are containers made of glass, plastic, borosilicate or related substances, and topped by special caps or stoppers. They are intended to contain chemicals in liquid or powder form for laboratories and stored in cabinets or on shelves. Some reagent bottles are tinted amber (actinic), brown or red to protect light-sensitive chemical compounds from visible light, ultraviolet and infrared radiation which may alter them; other bottles are tinted blue or uranium green for decorative purposes -mostly vintage apothecary sets, from centuries in which a doctor or apothecary was a prominent figure. The bottles are called "graduated" when they have marks on the sides indicating the approximate amount of liquid at a given level within the container. A reagent bottle is a type of laboratory glassware. The term "reagent" refers to a substance that is part of a chemical reaction, and "media" is the plural form of "medium" which refers to the liquid or gas which a reaction happens within, or is a processing chemical tool such as a flux.

<span class="mw-page-title-main">Flacon</span> Small, often decorative, bottle

A flacon is a small, often decorative, bottle. It has an opening seal or stopper and is designed to hold valuable liquids which may deteriorate upon contact with the air. They are widespread in the food industry, the pharmaceutical industry, and the cosmetics industry. They are generally made of glass for perfumes, but can also be made out of plastics for other uses.

References

  1. "Fiole miniature" (in French). Louvre Museum . Retrieved 14 July 2013.
  2. "Vial at Merriam-Webster's Online Dictionary". Merriam-Webster. Retrieved 15 September 2012.
  3. "Phiale". About.com. Archived from the original on 5 March 2012. Retrieved 4 June 2012.
  4. "Cappers". Pharmaceutical Online. Retrieved 8 March 2013.

Bibliography