N-acetyllactosamine synthase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.1.90 | ||||||||
CAS no. | 9054-94-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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N-acetyllactosamine synthase is a galactosyltransferase enzyme. [1] [2] [3] [4] [5] [6] It is a component of lactose synthase [ citation needed ] This enzyme modifies the connection between two molecule UDP-galactose and N-actyl-D-glucosamine and generates two different molecules UDP and N-acetyllactosamine as products. [7] The main function of the enzyme is associated with the biosynthesis of glycoproteins and glycolipids in both human and animals. [7] In human, the activity of this enzyme can be found in Golgi apparatus. [7]
It is classified under EC 2.4.1.90.
The lack of this enzyme leads to glycolysation [7] [8] [9] which is a serious neurological disease. The nature of the disease causes fluid in the brain, abnormal inflammatory response and abnormal bleeding issues. [7] [8] [9]