Pseudounipolar neuron

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Pseudounipolar neuron
Pseudounipolar bipolar neurons.svg
1: Pseudounipolar neuron; 2: Bipolar neuron
Details
System Nervous system
Identifiers
Latin neuron pseudounipolare
TH H2.00.06.1.00047
Anatomical terms of neuroanatomy

A pseudounipolar neuron is a type of neuron which has one extension from its cell body. This type of neuron contains an axon that has split into two branches. A single process arises from the cell body and then divides into an axon and a dendrite. They develop embryologically as bipolar in shape, and are thus termed pseudounipolar instead of unipolar. [1]

Contents

Structure

A pseudounipolar neuron has one axon that projects from the cell body for relatively a very short distance, before splitting into two branches. Pseudounipolar neurons are sensory neurons that have no dendrites, the branched axon serving both functions. [2] The peripheral branch extends from the cell body to organs in the periphery including skin, joints and muscles, and the central branch extends from the cell body to the spinal cord. [3]

In the dorsal root ganglia

The cell body of a pseudounipolar neuron is located within a dorsal root ganglion. [2] The axon leaves the cell body (and out of the dorsal root ganglion) into the dorsal root, where it splits into two branches. The central branch goes to the dorsal columns of the spinal cord, where it forms synapses with other neurons. The peripheral branch travels through the distal dorsal root into the spinal nerve all the way until skin, joint, and muscle.

In most sensory ganglia of cranial nerves

Pseudounipolar neurons are found in the sensory ganglia of most cranial nerves.

Specifically the:

Pseudounipolar neurons in cranial nerve sensory ganglia synapse in the main sensory trigeminal nucleus, spinal trigeminal nucleus or solitary nucleus.

While the vestibulocochlear nerve has two ganglia associated with it (spiral ganglion and vestibular ganglion), both contain bipolar neurons, not pseudounipolar.

In the mesencephalic nucleus

The mesencephalic nucleus is made up of pseudounipolar neurons which migrated into the brainstem during embryological development. It is the only location in the central nervous system where the cell bodies of pseudounipolar neurons are found.

Function

All pseudounipolar neurons are sensory neurons. The ones found in the dorsal root ganglia, and majority of those in cranial nerve sensory ganglia carry information about touch, vibration, proprioception, pain and temperature.

Pseudounipolar neurons in the geniculate ganglion, inferior ganglion of the glossopharyngeal nerve and inferior ganglion of the vagus nerve also carry information about taste from taste buds.

Some of the pseudounipolar neurons in the inferior ganglion of the glossopharyngeal nerve carry information from the carotid body and carotid sinus.

The pseudounipolar neurons in the mesencephalic nucleus carry proprioceptive information from the muscle of mastication.

See also

Related Research Articles

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<span class="mw-page-title-main">Dorsal column–medial lemniscus pathway</span> Sensory spinal pathway

The dorsal column–medial lemniscus pathway (DCML) is a sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (position) from the skin and joints. It transmits information from the body to the primary somatosensory cortex in the postcentral gyrus of the parietal lobe of the brain. The pathway receives information from sensory receptors throughout the body, and carries this in nerve tracts in the white matter of the dorsal column of the spinal cord to the medulla, where it is continued in the medial lemniscus, on to the thalamus and relayed from there through the internal capsule and transmitted to the somatosensory cortex. The name dorsal-column medial lemniscus comes from the two structures that carry the sensory information: the dorsal columns of the spinal cord, and the medial lemniscus in the brainstem.

<span class="mw-page-title-main">Cochlear nucleus</span> Two cranial nerve nuclei of the human brainstem

The cochlear nuclear (CN) complex comprises two cranial nerve nuclei in the human brainstem, the ventral cochlear nucleus (VCN) and the dorsal cochlear nucleus (DCN). The ventral cochlear nucleus is unlayered whereas the dorsal cochlear nucleus is layered. Auditory nerve fibers, fibers that travel through the auditory nerve carry information from the inner ear, the cochlea, on the same side of the head, to the nerve root in the ventral cochlear nucleus. At the nerve root the fibers branch to innervate the ventral cochlear nucleus and the deep layer of the dorsal cochlear nucleus. All acoustic information thus enters the brain through the cochlear nuclei, where the processing of acoustic information begins. The outputs from the cochlear nuclei are received in higher regions of the auditory brainstem.

<span class="mw-page-title-main">Inferior ganglion of glossopharyngeal nerve</span>

The inferior ganglion of the glossopharyngeal nerve is a sensory ganglion. It is larger than and inferior to the superior ganglion of the glossopharyngeal nerve. It is located within the jugular foramen.

<span class="mw-page-title-main">Superior ganglion of vagus nerve</span>

The superior ganglion of the vagus nerve, (jugular ganglion) is a sensory ganglion of the peripheral nervous system. It is located within the jugular foramen, where the vagus nerve exits the skull. It is smaller than and proximal to the inferior ganglion of the vagus nerve.

<span class="mw-page-title-main">Superior ganglion of glossopharyngeal nerve</span>

The superior ganglion of the glossopharyngeal nerve is a sensory ganglion of the peripheral nervous system. It is located within the jugular foramen where the glossopharyngeal nerve exits the skull. It is smaller than and superior to the inferior ganglion of the glossopharyngeal nerve.

<span class="mw-page-title-main">Inferior ganglion of vagus nerve</span> Ganglion of the peripheral nervous system

The inferior ganglion of the vagus nerve is a sensory ganglion of the peripheral nervous system. It is located within the jugular foramen where the vagus nerve exits the skull. It is larger than and below the superior ganglion of the vagus nerve.

<span class="mw-page-title-main">Mesencephalic nucleus of trigeminal nerve</span>

The mesencephalic nucleus of trigeminal nerve is one of the sensory nuclei of the trigeminal nerve. It is located in the brainstem. It receives proprioceptive sensory information from the muscles of mastication and other muscles of the head and neck. It is involved in processing information about the position of the jaw/teeth. It is functionally responsible for preventing excessive biting that may damage the dentition, regulating tooth pain preception, and mediating the jaw jerk reflex.

<span class="mw-page-title-main">Outline of the human nervous system</span> Overview of and topical guide to the human nervous system

The following Diagram is provided as an overview of and topical guide to the human nervous system:

References

  1. Gold, M. S.; Caterina, M. J. (2008-01-01), Masland, Richard H.; Albright, Thomas D.; Albright, Thomas D.; Masland, Richard H. (eds.), "5.04 - Molecular Biology of the Nociceptor/Transduction", The Senses: A Comprehensive Reference, New York: Academic Press, pp. 43–73, doi:10.1016/b978-012370880-9.00141-9, ISBN   978-0-12-370880-9, S2CID   83393483 , retrieved 2020-11-18
  2. 1 2 MacCallum, Don. "Peripheral Nervous System". Histology and Virtual Microscopy Learning Resources. University of Michigan Medical School. Archived from the original on 7 July 2014. Retrieved 24 June 2014.
  3. Kandel, Eric R.; Schwartz, James H.; Mack, Thomas M. Jessell (2000). Principles of neural Science (4th ed.). Cambridge: McGraw Hill. p.  24. ISBN   978-0838577011.