Garcinia gummi-gutta

Last updated

Garcinia gummi-gutta
kuttppulli.JPG
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Malpighiales
Family: Clusiaceae
Genus: Garcinia
Species:
G. gummi-gutta
Binomial name
Garcinia gummi-gutta
Synonyms [1]
  • Cambogia binucao Blanco
  • Cambogia gemmi-gutta L.
  • Cambogia solitaria Stokes
  • Garcinia affinis Wight & Arn.
  • Garcinia cambogia(Gaertn.) Desr.
  • Garcinia sulcata Stokes

Garcinia gummi-gutta is a tropical species of Garcinia native to South Asia and Southeast Asia. [1] [2] Common names include Garcinia cambogia (a former scientific name), as well as brindle berry, and Malabar tamarind. [3] The fruit looks like a small pumpkin and is green to pale yellow in color. [4]

Contents

Although it has received considerable media attention purporting its effects on weight loss, there are reports of liver toxicity associated with the Hydroxycut commercial preparation containing the fruit extract, with clinical evidence indicating it has no significant effect on weight loss. [3] [4] [5]

Cultivation

In Kerala, India Garcinia gummi-gutta in Aanakkulam.jpg
In Kerala, India
Ripe fruit Kudampuli Yellow.jpg
Ripe fruit

Garcinia gummi-gutta is grown for its fruit in Southeast Asia and South Asia. Garcinia gummi-gutta is one of several closely related Garcinia species from the plant family Clusiaceae. [1] [2] With thin skin and deep vertical lobes, the fruit of G. gummi-gutta and related species range from about the size of an orange to that of a grapefruit; G. gummi-gutta looks more like a small yellowish, greenish, or sometimes reddish pumpkin. [6] The color can vary considerably. When the rinds are dried and cured in preparation for storage and extraction, they are dark brown or black in color.[ citation needed ]

Phytochemicals

Although few high-quality studies have been done to define the composition of the fruit, its phytochemical content includes hydroxycitric acid which is extractable and developed as a dietary supplement. [4] [5] [7] Other compounds identified in the fruit include the polyphenols, luteolin, and kaempferol. [8]

Common names

In the Malabar Coast, it is known as kudam puli and in Tamil speaking areas of Sri Lanka and India, it is called goraka. [9] [10]

Weight loss claims

In late 2012, a United States celebrity doctor, Dr. Oz, promoted Garcinia cambogia extract as "an exciting breakthrough in natural weight loss". [11] [12] Dr. Oz's endorsements of dietary supplements having no or little scientific evidence of efficacy have often led to a substantial increase in consumer purchases of the promoted products. [12]

While it has received considerable media attention purporting impact on weight loss, the evidence for Garcinia cambogia supports no clear effect, [3] [4] [13] [14] while gastrointestinal adverse events were two-fold more common over the placebo in a 2011 meta-analysis, indicating the extract may be unsafe for human consumption. [4] [5] Adverse events associated with use of such supplements ("side effects") — especially, liver toxicity, as well as gastrointestinal issues — led to one preparation being withdrawn from the market. [15]

Adverse effects

In addition to possible liver damage, hydroxycitric acid can cause dry mouth, nausea, gastrointestinal discomfort, and headaches. [4] [16]

At least one other published medical study seem to contradict the above assertion:

The structure, mechanism of action, long history of the use of Garcinia/HCA and comprehensive scientific evidence had shown “no observed adverse effect level (NOAEL)” at levels up to 2800 mg/day, suggesting its safety for use. [17]

Drug interactions

There is potential for Garcinia cambogia to interfere with prescription medications, including those used to treat people with diabetes, asthma, and clotting disorders. [4]

Culinary

When the fruit is sun dried for several days, it becomes black with a shrivelled body Sun Dried and Smoked Gambooge Close Up.jpg
When the fruit is sun dried for several days, it becomes black with a shrivelled body

Garcinia gummi-gutta is used in cooking, including in the preparation of curries to add a sour flavor. [4] The fruit rind and extracts of Garcinia species are used in many traditional recipes used in food preparation in Southeast Asian countries. [3] [18] In the Indian Ayurvedic medicine, "sour" flavors are said to activate digestion. The extract and rind of G. gummi-gutta is a curry condiment in India. [18] [19] [20] It is an essential souring ingredient in the southern Thai variant of kaeng som , a sour curry. [21] [22]

See also

Related Research Articles

<i>Garcinia</i> Genus of flowering plants

Garcinia is a genus of flowering plants in the family Clusiaceae native to Asia, America, Australia, tropical and southern Africa, and Polynesia. The number of species is disputed; Plants of the World Online (POWO) recognise up to 400. Commonly, the plants in this genus are called saptrees, mangosteens, or garcinias, and is one of several plants known as by the name "monkey fruit".

<i>Actaea racemosa</i> Species of plant

Actaea racemosa, the black cohosh, black bugbane, black snakeroot, rattle-top, or fairy candle, is a species of flowering plant of the family Ranunculaceae. It is native to eastern North America from the extreme south of Ontario to central Georgia, and west to Missouri and Arkansas. It grows in a variety of woodland habitats, and is often found in small woodland openings. The roots and rhizomes were used in traditional medicine by Native Americans. Its extracts are manufactured as herbal medicines or dietary supplements. Most dietary supplements containing black cohosh are not well-studied or recommended for safe and effective use in treating menopause symptoms or any disease. In contrast, some herbal medicinal products containing black cohosh extract hold a marketing authorization in several states of the European Union and are well-studied and recommended for safe and effective use for the relief of menopausal symptoms such as hot flushes and profuse sweating attacks. Such differentiation between the product types seems to be important.

<span class="mw-page-title-main">Bitter orange</span> Hybrid citrus plant

Bitter orange, sour orange, Seville orange, bigarade orange, or marmalade orange is the citrus tree Citrus × aurantium and its fruit. It is native to Southeast Asia and has been spread by humans to many parts of the world. It is probably a cross between the pomelo, Citrus maxima, and the mandarin orange, Citrus reticulata.

<span class="mw-page-title-main">Gamboge</span>

Gamboge is a deep yellow pigment derived from a species of tree that primarily grows in Cambodia. Popular in east Asian watercolor works, it has been used across a number of media dating back to the 8th century. Easy to transport and manipulate into a durable watercolor paint, amboge is notable for its versatility as a pigment in how it has been used in paintings, printing of books, and garment dyes, including the robes of Buddhist monks. Though used in a number of different contexts, Gamboge is known not to react well with lime surfaces therefore making it unsuitable for frescos and with white lead. For its popularity, Gamboge has not been extensively identified in works of art from any time period; the few instances wherein art historians have attempted to identify whether or not the pigment was used in a given work have confirmed its widespread use and its longevity as staple within watercolor painting particularly in eastern art.

<i>Gymnema sylvestre</i> Species of flowering plant

Gymnema sylvestre is a perennial woody vine native to Asia, Africa and Australia. It has been used in Ayurvedic medicine. Common names include gymnema, Australian cowplant, and Periploca of the woods, and the Hindi term gurmar, which means "sugar destroyer".

Grapefruit seed extract (GSE), also known as citrus seed extract, is a liquid extract derived from the seeds, pulp, and white membranes of grapefruit. GSE is prepared by grinding the grapefruit seed and juiceless pulp, then mixing with glycerin. Commercially available GSEs sold to consumers are made from the seed, pulp, and glycerin blended together. GSE is sold as a dietary supplement and is used in cosmetics.

<span class="mw-page-title-main">Prune juice</span>

Prune juice is a fruit juice derived from prunes that have been rehydrated. It is a mass-produced product that is often produced using a hot extraction method, and juice concentrate is typically produced using a low-temperature extraction method. It may be used as a dietary supplement to act as a laxative. It is also sometimes used as a flavor enhancer in tobacco products. It is an ingredient in many cocktails, such as the Purple Dragon, or Constipolitan.

<span class="mw-page-title-main">Thai curry</span> Dishes in Thai cuisine made with curry paste

Thai curry is a dish in Thai cuisine made from curry paste, coconut milk or water, meat, seafood, vegetables or fruit, and herbs. Curries in Thailand mainly differ from the curries in India in their use of ingredients such as herbs and aromatic leaves over a mix of spices.

<i>Sandoricum koetjape</i> Species of tree

Sandoricum koetjape, the santol, sentul or cotton fruit, is a tropical fruit native to maritime Southeast Asia (Malesia).

<span class="mw-page-title-main">Hydroxycitric acid</span> Chemical compound

Hydroxycitric acid (HCA) is a derivative of citric acid that is found in a variety of tropical plants including Garcinia cambogia and Hibiscus sabdariffa.

<i>Garcinia kola</i> Species of tree

Garcinia kola (bitter kola is a species of flowering plant belonging to the Mangosteen genus Garcinia of the family Clusiaceae. It is found in Benin, Cameroon, The Gambia, Democratic Republic of the Congo, Ivory Coast, Mali, Gabon, Ghana, Liberia, Nigeria, Senegal and Sierra Leone. Its natural habitat is subtropical or tropical moist lowland forests.

<span class="mw-page-title-main">Preserved lemon</span> Type of pickle

Preserved lemon or lemon pickle is a condiment that is common in the cuisines of Indian subcontinent and Morocco. It was also found in 18th-century English cuisine.

<i>Garcinia dulcis</i> Species of tree

Garcinia dulcis is a tropical fruit tree native to the Philippines, Java, Lesser Sunda Islands, eastern Indonesia, and Papua New Guinea. It was domesticated early and spread inland into mainland Asia. It is commonly known as mundu or munu in Indonesia and Malaysia, baniti or taklang-anak in the Philippines, and maphuut or ma phut in Thailand.

<i>Garcinia morella</i> Species of flowering plant

Garcinia morella is a species of tree in the family Clusiaceae found in India, and Sri Lanka.

<i>Garcinia atroviridis</i> Species of tree

Garcinia atroviridis, known as asam gelugur, asam gelugo, or asam keping is a large rainforest tree native to Peninsular Malaysia and Sumatra. This species grows wild throughout Peninsular Malaysia but is also widely cultivated, especially in the northern states, owing to its economic and medicinal value. Garcinia atroviridis is a large perennial plant commonly found in evergreen forests in the southern region of Thailand and Malaysia.

<i>Garcinia indica</i> Species of tree

Garcinia indica, a plant in the mangosteen family (Clusiaceae), commonly known as kokum, is a fruit-bearing tree that has culinary, pharmaceutical, and industrial uses. It primarily grows in the Western Ghats, especially the Goa and Konkan region.

<span class="mw-page-title-main">Gambogic acid</span> Chemical compound

Gambogic acid is a xanthonoid that is derived from the brownish or orange resin from Garcinia hanburyi. Garcinia hanburyi is a small to medium-sized evergreen tree with smooth grey bark. It is native to Cambodia, southern Vietnam, and Thailand and has been successfully introduced in Singapore.

<i>Kaeng som</i> Fish curry dish

Kaeng som or gaeng som or Asam rebus or Thai/Lao/Malaysian sour curry is a sour and spicy fish curry or soup with vegetables popular in Southeast Asia. The curry is characteristic for its sour taste, which comes from tamarind (makham). The recipe uses palm sugar to sweeten the curry.

Dangyuja is a Korean citrus fruit that is a specialty of Jeju Island. In Jeju language, it is called daengyuji. Dangyuja has a similar shape and flavour to yuzu, but is genealogically a variety of pomelo.

Garcinia binucao is a species of flowering plant in the Clusiaceae family. It is commonly known as binukaw or batuan, is a species of Garcinia endemic to the Philippines. It is not cultivated, though its edible fruits are harvested from the wild for use as a souring agent in some Filipino dishes.

References

  1. 1 2 3 "Garcinia gummi-gutta (L.) N.Robson". World Checklist of Selected Plant Families . Royal Botanic Gardens, Kew . Retrieved 1 June 2013 via The Plant List. Note that this website has been superseded by World Flora Online
  2. 1 2 "Garcinia gummi-gutta". Germplasm Resources Information Network . Agricultural Research Service, United States Department of Agriculture . Retrieved 11 December 2017.
  3. 1 2 3 4 "Garcinia cambogia". National Center for Complementary and Integrative Health, US National Institutes of Health. 1 December 202. Retrieved 25 September 2021.
  4. 1 2 3 4 5 6 7 8 "Garcinia cambogia". Drugs.com. 28 May 2020. Retrieved 25 September 2021.
  5. 1 2 3 Onakpoya, Igho; Hung, Shao Kang; Perry, Rachel; Wider, Barbara; Ernst, Edzard (2011). "The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials". Journal of Obesity. 2011 (December 14): 509038. doi: 10.1155/2011/509038 . PMC   3010674 . PMID   21197150.
  6. "Fruit yellowish or reddish, size of an orange having six or eight deep longitudinal grooves in its fleshy pericarp. Pulp acid of a pleasant flavor. It is dried among the Singalese who use it in curries." Uphof, J.C. Th. (1968).
  7. Yamada T, Hida H, Yamada Y (2007). "Chemistry, physiological properties, and microbial production of hydroxycitric acid". Appl. Microbiol. Biotechnol. 75 (5): 977–82. doi:10.1007/s00253-007-0962-4. PMID   17476502. S2CID   25194835.
  8. Sulaiman, C. T; Balachandran, I (2017). "LC/MS characterization of phenolic antioxidants of Brindle berry (Garcinia gummi-gutta (L.) Robson)". Natural Product Research. 31 (10): 1191–1194. doi:10.1080/14786419.2016.1224871. PMID   27583573. S2CID   29342259.
  9. Sarip, Nur Aqilah; Aminudin, Nurul Iman; Danial, Wan Hazman (12 September 2021). "Green synthesis of metal nanoparticles using Garcinia extracts: a review". Environmental Chemistry Letters. 20: 1. doi:10.1007/s10311-021-01319-3. S2CID   237487258.
  10. Pramanik, Malay; Diwakar, Atul Kumar; Dash, Poli; Szabo, Sylvia; Pal, Indrajit (1 April 2021). "Conservation planning of cash crops species (Garcinia gummi-gutta) under current and future climate in the Western Ghats, India". Environment, Development and Sustainability. 23 (4): 1. doi:10.1007/s10668-020-00819-6. S2CID   220051712.
  11. The Dr. Oz Show (November 5, 2012). Garcinia Cambogia: The Newest, Fastest Fat-Buster Archived 2014-04-21 at the Wayback Machine .
  12. 1 2 Christensen, Jen; Wilson Jacque (19 June 2014). "Congressional hearing investigates Dr. Oz 'miracle' weight loss claims". CNN Health. Retrieved 18 September 2016.
  13. Heymsfield, S. B.; Allison, D. B.; Vasselli, J. R.; Pietrobelli, A.; Greenfield, D.; Nunez, C. (1998). "Garcinia cambogia (Hydroxycitric Acid) as a Potential Antiobesity Agent: A Randomized Controlled Trial". J. Am. Med. Assoc. 280 (18): 1596–1600. doi: 10.1001/jama.280.18.1596 . PMID   9820262.
  14. Crescioli, Giada; Lombardi, Niccolò; Bettiol, Alessandra; Marconi, Ettore; Risaliti, Filippo; Bertoni, Michele; Menniti Ippolito, Francesca; Maggini, Valentina; Gallo, Eugenia; Firenzuoli, Fabio; Vannacci, Alfredo (2018-05-25). "Acute liver injury following Garcinia cambogia weight-loss supplementation: case series and literature review". Internal and Emergency Medicine. 13 (6): 857–872. doi:10.1007/s11739-018-1880-4. hdl: 2158/1244214 . ISSN   1828-0447. PMID   29802521. S2CID   44094323.
  15. Lobb, A. (2009). "Hepatoxicity associated with weight-loss supplements: A case for better post-marketing surveillance". World Journal of Gastroenterology. 15 (14): 1786–1787. doi:10.3748/wjg.15.1786. PMC   2668789 . PMID   19360927.
  16. Soni, MG (2004). "Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt". Food Chem Toxicol. 42 (9): 1513–29. doi:10.1016/j.fct.2004.04.014. PMID   15234082.
  17. Chuah, Li Oon; Yeap, Swee Keong; Ho, Wan Yong; Beh, Boon Kee; Alitheen, Noorjahan Banu (2012). "In Vitro and In Vivo Toxicity of Garcinia or Hydroxycitric Acid: A Review". Evidence-Based Complementary and Alternative Medicine. 2012: 197920. doi: 10.1155/2012/197920 . ISSN   1741-427X. PMC   3424601 . PMID   22924054.
  18. 1 2 "The acid rinds of the ripe fruit are eaten,." Drury, Heber (1873). "Garcinia gambogia (Desrous) N. 0. Clusiaceae". The Useful Plants of India, second edition. London: William H. Allen & Co. p. 220.
  19. "G. Gummi-Gutta (Garcinia Cambogia) – An Ancient Indian Curry Condiment". US Premium Garcinia Cambogia. Archived from the original on 31 January 2019. Retrieved 5 May 2015.
  20. "Kudampuli meencurry (fish curry with Malabar tamarind)". Secret Indian Recipe. Retrieved 5 May 2015.
  21. "Kaeng Som Kung (Sour Curry with Shrimp)". Saveur. 26 February 2015. Retrieved 5 May 2015.
  22. "Gaeng Som Recipe, Thai Sour Curry Recipe of Shrimp, Okra and Roselle Leaves". Thai Food Master. 30 March 2011. Retrieved 5 May 2015.