Notoungulata is an extinct order of ungulates that inhabited South America from the early Paleocene to the end of the Pleistocene, living from approximately 61 million to 11,000 years ago. Notoungulates were morphologically diverse, with forms resembling animals as disparate as rabbits and rhinoceroses. Notoungulata are the largest group of South American native ungulates, with over 150 genera in 14 families having been described, divided into two major subgroupings, Typotheria and Toxodontia. Notoungulates first diversified during the Eocene. Their diversity declined from the late Neogene onwards, with only the large toxodontids persisting until the end of the Pleistocene, perishing as part of the Late Pleistocene megafauna extinctions along with most other large mammals across the Americas. Collagen sequence analysis suggests that notoungulates are closely related to litopterns, another group of South American ungulates, and their closest living relatives being perissodactyls, including rhinoceroses, tapirs and equines as part of the clade Panperissodactyla. However their relationships to other South American ungulates are uncertain. Several groups of notoungulates separately evolved ever-growing cheek teeth.
Leontiniidae is an extinct family comprising eighteen genera of notoungulate mammals known from the Middle Eocene (Mustersan) to Late Miocene (Huayquerian) of South America.
Toxodontidae is an extinct family of notoungulate mammals, known from the Oligocene to the Holocene of South America, with one genus, Mixotoxodon, also known from the Pleistocene of Central America and southern North America. Member of the family were medium to large-sized, ranging from around 350–400 kilograms (770–880 lb) in Nesodon to 1,000–1,200 kilograms (2,200–2,600 lb) in Toxodon, and had medium to high-crowned dentition, which in derived members of the group evolved into ever-growing cheek teeth. Isotopic analyses have led to the conclusion that Pleistocene members of the family were flexible mixed feeders.
Mesotheriidae is an extinct family of notoungulate mammals known from the Oligocene through the Pleistocene of South America. Mesotheriids were small to medium-sized herbivorous mammals adapted for digging.
Notioprogonia is a suborder of the extinct mammalian order Notoungulata and includes two families, Henricosborniidae and Notostylopidae.
Nesodon is a genus of Miocene mammal belonging to the extinct order Notoungulata which inhabited southern South America during the Late Oligocene to Miocene living from 29.0 to 16.3 Ma and existed for approximately 12.7 million years. It had a relatively large size, weighing up to 554 kg (1221 lbs) and reaching 1.5 m in height.
Piauhytherium is an extinct genus of herbivorous notoungulate mammal of the family Toxodontidae. It lived during the Late Pleistocene; fossils have been found in Brazil. The only known species is Piauhytherium capivarae.
Prosotherium is an extinct genus of late Oligocene hegetotheriid notoungulate. It has been found in two Argentinian fossil formations, ie, the Sarmiento Formation in Chubut Province, and the Agua de la Piedra Formation in Mendoza Province.
Gualta is an extinct genus of leontiniid notoungulates. It lived during the Late Oligocene of what is now Argentina.
Pleurostylodon is an extinct genus of notoungulate belonging to the family Isotemnidae. It lived during the Middle Eocene, in what is now Argentina.
Eomorphippus is an extinct genus of notohippid notoungulate that lived from the Late Eocene to the Early Oligocene in what is today South America.
Eurygenium is an extinct genus of notoungulate belonging to the family Notohippidae. It lived during the Late Oligocene in what is today South America.
Anayatherium is an extinct genus of notoungulate belonging to the family Leontiniidae. It lived during the Late Oligocene, and its fossilized remains were discovered in South America.
Colpodon is an extinct genus of herbivorous mammal, belonging to the order Notoungulata. It lived during the Early Miocene, in what is today Argentina and Chile, in South America.
Elmerriggsia is an extinct genus of Notoungulate, belonging to the family Leontiniidae. It lived during the Late Oligocene in South America.
Martinmiguelia is an extinct genus of Notoungulate, belonging to the family Leontiniidae. It lived during the Middle Eocene, and its fossil remains were found in South America.
Pascualihippus is an extinct genus of notoungulate belonging to the family Notohippidae. It lived during the Late Oligocene, in what is now Bolivia.
Teushentherium is an extinct genus of notohippid notoungulate from the Oligocene of Argentina. Fossils have been found in the Sarmiento Formation of Argentina.
Rosendo is an extinct genus of notohippid notoungulates that lived during the Early Oligocene in what is now Argentina and Chile. Fossils of this genus have been found in the Sarmiento Formation and the Abanico Formations of Argentina and Chile.
Moqueguahippus is an extinct genus of notohippid notoungulates that lived during the Late Oligocene of what is now Peru. Fossils of this genus have been found in the Moquegua Formation of Peru, which it was named after.
