ATP10A

Last updated
ATP10A
Identifiers
Aliases ATP10A , ATP10C, ATPVA, ATPVC, ATPase phospholipid transporting 10A (putative)
External IDs OMIM: 605855 MGI: 1330809 HomoloGene: 56461 GeneCards: ATP10A
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024490

NM_009728

RefSeq (protein)

NP_077816

NP_033858

Location (UCSC) Chr 15: 25.68 – 25.87 Mb Chr 7: 58.66 – 58.83 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable phospholipid-transporting ATPase VA also known as ATPase class V type 10A (ATP10A) or aminophospholipid translocase VA is an enzyme that in humans is encoded by the ATP10A gene. [5] [6] [7]

Contents

Function

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene is maternally expressed. It maps within the most common interval of deletion responsible for Angelman syndrome, also known as 'happy puppet syndrome'. [7]

See also

Related Research Articles

ATP8B1

Probable phospholipid-transporting ATPase IC is an enzyme that in humans is encoded by the ATP8B1 gene. This protein is associated with progressive familial intrahepatic cholestasis type 1 as well as benign recurrent intrahepatic cholestasis.

ATP2C1

Calcium-transporting ATPase type 2C member 1 is an enzyme that in humans is encoded by the ATP2C1 gene.

ATP1B1

Sodium/potassium-transporting ATPase subunit beta-1 is an enzyme that in humans is encoded by the ATP1B1 gene.

ATP2A3

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 is an enzyme that in humans is encoded by the ATP2A3 gene.

ATP1A4

Sodium/potassium-transporting ATPase subunit alpha-4 is an enzyme that in humans is encoded by the ATP1A4 gene.

ATP6V1D

V-type proton ATPase subunit D is an enzyme that in humans is encoded by the ATP6V1D gene.

ATP12A

ATPase, H+/K+ transporting, nongastric, alpha polypeptide is a protein that in humans is encoded by the ATP12A gene.

ATP6V0A2

V-type proton ATPase 116 kDa subunit a isoform 2 also known as V-ATPase 116 kDa isoform a2 is an enzyme that in humans is encoded by the ATP6V0A2 gene.

ATP2B3

Plasma membrane calcium-transporting ATPase 3 is an enzyme that in humans is encoded by the ATP2B3 gene.

Renin receptor

The renin receptor also known as ATPase H(+)-transporting lysosomal accessory protein 2, or the prorenin receptor, is a protein that in humans is encoded by the ATP6AP2 gene.

ATP1B3

Sodium/potassium-transporting ATPase subunit beta-3 is an enzyme that in humans is encoded by the ATP1B3 gene. ATP1B3 has also been designated as CD298.

ATP5G2

The ATP5MC2 gene is one of three human paralogs that encode membrane subunit c of the mitochondrial ATP synthase.

ATP13A3

Probable cation-transporting ATPase 13A3 is an enzyme that in humans is encoded by the ATP13A3 gene.

ATP5O

ATP synthase subunit O, mitochondrial is an enzyme that in humans is encoded by the ATP5PO gene.

ATP6V1E2

V-type proton ATPase subunit E 2 is an enzyme that in humans is encoded by the ATP6V1E2 gene.

FRAS1

Extracellular matrix protein FRAS1 is a protein that in humans is encoded by the FRAS1 gene. This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development.

NIPA2

Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 is a protein that in humans is encoded by the NIPA2 gene.

RNASEH2A

Ribonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene.

CC2D2A

Coiled-coil and C2 domain-containing protein 2A that in humans is encoded by the CC2D2A gene.

ATP8B3

The human gene ATP8B3 encodes the protein ATPase, aminophospholipid transporter, class I, type 8B, member 3.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000206190 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025324 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Halleck MS, Lawler JF JR, Blackshaw S, Gao L, Nagarajan P, Hacker C, Pyle S, Newman JT, Nakanishi Y, Ando H, Weinstock D, Williamson P, Schlegel RA (Oct 2000). "Differential expression of putative transbilayer amphipath transporters". Physiol Genomics. 1 (3): 139–50. doi:10.1152/physiolgenomics.1999.1.3.139. PMID   11015572.
  6. Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Aug 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi: 10.1093/dnares/5.1.31 . PMID   9628581.
  7. 1 2 "Entrez Gene: ATP10A ATPase, Class V, type 10A".

Further reading