GNAT2

Last updated

GNAT2
Identifiers
Aliases GNAT2 , ACHM4, GNATC, G protein subunit alpha transducin 2, HG1D
External IDs OMIM: 139340; MGI: 95779; HomoloGene: 21092; GeneCards: GNAT2; OMA:GNAT2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005272
NM_001377295
NM_001379232

NM_008141

RefSeq (protein)

NP_005263
NP_001364224
NP_001366161

NP_032167

Location (UCSC) Chr 1: 109.6 – 109.62 Mb Chr 3: 108 – 108.01 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Guanine nucleotide-binding protein G(t) subunit alpha-2 is a protein that in humans is encoded by the GNAT2 gene. [5] [6]

Contents

Function

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000134183 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000009108 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Morris TA, Fong SL (Oct 1993). "Characterization of the gene encoding human cone transducin alpha-subunit (GNAT2)". Genomics. 17 (2): 442–8. doi: 10.1006/geno.1993.1345 . PMID   8406495.
  6. 1 2 "Entrez Gene: GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2".

Further reading