GNG5

GNG5
Identifiers
Aliases	GNG5 , G protein subunit gamma 5
External IDs	OMIM: 600874 MGI: 3783217 HomoloGene: 3861 GeneCards: GNG5
Gene location (Human)
Chr.	Chromosome 1 (human)
End	84,506,581 bp
RNA expression pattern
	Top expressed in
	left ventricle; ; right lung; ; upper lobe of left lung; ; gastrocnemius muscle; ; monocyte; ; body of stomach; ; bone marrow; ; ganglionic eminence; ; body of pancreas; ; spleen;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	PDZ domain binding ; protein binding ; GTPase activity ; signal transducer activity ; G-protein beta-subunit binding ;
Cellular component	extracellular exosome ; mitochondrion ; membrane ; heterotrimeric G-protein complex ; plasma membrane ; G-protein beta/gamma-subunit complex ;
Biological process	positive regulation of neural precursor cell proliferation ; positive regulation of secondary heart field cardioblast proliferation ; cellular response to glucagon stimulus ; signal transduction ; G protein-coupled receptor signaling pathway ;
	Sources:Amigo / QuickGO
Orthologs
	2787
	100043507
	ENSG00000174021
	n/a
	P63218
	Q80SZ7
	NM_005274
	n/a
	NP_005265
	NP_034448
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 19, 2023

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 is a protein that in humans is encoded by the GNG5 gene.^[4]^[5]

Related Research Articles

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene.

Guanine nucleotide-binding protein G(o) subunit alpha is a protein that in humans is encoded by the GNAO1 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 is a protein that in humans is encoded by the GNB2 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.

Guanine nucleotide-binding protein subunit beta-5 is a protein that in humans is encoded by the GNB5 gene. Alternatively spliced transcript variants encoding different isoforms exist.

Guanine nucleotide-binding protein G(t) subunit alpha-2 is a protein that in humans is encoded by the GNAT2 gene.

Guanine nucleotide-binding protein G(t) subunit alpha-1 is a protein that in humans is encoded by the GNAT1 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 is a protein that in humans is encoded by the GNG12 gene.

Guanine nucleotide-binding protein G(T) subunit gamma-T1 is a protein that in humans is encoded by the GNGT1 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 is a protein that in humans is encoded by the GNG3 gene.

Guanine nucleotide-binding protein subunit beta-4 is a protein that in humans is encoded by the GNB4 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 is a protein that in humans is encoded by the GNG11 gene.

Integral membrane protein 2A is a protein that in humans is encoded by the ITM2A gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 is a protein that in humans is encoded by the GNG7 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 is a protein that in humans is encoded by the GNG13 gene.

28S ribosomal protein S24, mitochondrial is a protein that in humans is encoded by the MRPS24 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 is a protein that in humans is encoded by the GNGT2 gene.

28S ribosomal protein S17, mitochondrial is a protein that in humans is encoded by the MRPS17 gene.

Di-N-acetylchitobiase is an enzyme that in humans is encoded by the CTBS gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000174021 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ahmad W, Li S, Chen H, Tuck-Muller CM, Pittler SJ, Aronson NN Jr (Aug 1995). "Lysosomal chitobiase (CTB) and the G-protein gamma 5 subunit (GNG5) genes co-localize to human chromosome 1p22". Cytogenet Cell Genet. 71 (1): 44–6. doi:10.1159/000134059. PMID 7606925.
↑ "Entrez Gene: GNG5 guanine nucleotide binding protein (G protein), gamma 5".

Fisher KJ, Aronson NN (1992). "Characterization of the cDNA and genomic sequence of a G protein gamma subunit (gamma 5)". Mol. Cell. Biol. 12 (4): 1585–91. doi:10.1128/mcb.12.4.1585. PMC 369601 . PMID 1549114.
Yan K, Kalyanaraman V, Gautam N (1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.
Mao M, Fu G, Wu JS, et al. (1998). "Identification of genes expressed in human CD34+ hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175–80. Bibcode:1998PNAS...95.8175M. doi: 10.1073/pnas.95.14.8175 . PMC 20949 . PMID 9653160.
Liu B, Aronson NN (1998). "Structure of human G protein G gamma 5 gene GNG5". Biochem. Biophys. Res. Commun. 251 (1): 88–94. doi:10.1006/bbrc.1998.9439. PMID 9790912.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934 . PMID 11042152.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Cuello F, Schulze RA, Heemeyer F, et al. (2003). "Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta". J. Biol. Chem. 278 (9): 7220–6. doi: 10.1074/jbc.M210304200 . PMID 12486123.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID 16710414.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000174021 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7606925-4] Ahmad W, Li S, Chen H, Tuck-Muller CM, Pittler SJ, Aronson NN Jr (Aug 1995). "Lysosomal chitobiase (CTB) and the G-protein gamma 5 subunit (GNG5) genes co-localize to human chromosome 1p22". Cytogenet Cell Genet. 71 (1): 44–6. doi:10.1159/000134059. PMID 7606925.

[entrez-5] "Entrez Gene: GNG5 guanine nucleotide binding protein (G protein), gamma 5".

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GNG5

Related Research Articles

References

Further reading