| bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.1.17 | ||||||||
| CAS no. | 37289-29-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) is an enzyme that catalyzes the chemical reaction
- P1,P4-bis(5'-guanosyl) tetraphosphate + H2O GTP + GMP
Thus, the two substrates of this enzyme are P1,P4-bis(5'-guanosyl) tetraphosphate and H2O, whereas its two products are GTP and GMP.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase. Other names in common use include bis(5'-guanosyl)-tetraphosphatase, bis(5'-adenosyl)-tetraphosphatase, diguanosinetetraphosphatase (asymmetrical), dinucleosidetetraphosphatase (asymmetrical), diadenosine P1,P4-tetraphosphatase, dinucleoside tetraphosphatase, and 1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase. This enzyme participates in purine metabolism and pyrimidine metabolism.
