Megasphaera

Not to be confused with Magosphaera.

Megasphaera
Scientific classification
Domain:	Bacteria
Kingdom:	Bacillati
Phylum:	Bacillota
Class:	Negativicutes
Order:	Veillonellales
Family:	Veillonellaceae
Genus:	Megasphaera Rogosa 1971
Type species
Megasphaera elsdenii (Gutierrez et al. 1959) Rogosa 1971 [1]
Species
See text

Megasphaera is a genus of Bacillota bacteria classified within the class Negativicutes. ^{[1] [2]}

This classification has been reexamined. ^[3] This genus appears to be a member of the Clostridia .

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) ^[1] and the National Center for Biotechnology Information (NCBI). ^[2]

16S rRNA based LTP_10_2024 [4] [5] [6]

120 marker proteins based GTDB 09-RS220 [7] [8] [9]

Megasphaera M. micronuciformisMarchandin et al. 2003 Anaeroglobus geminatusCarlier et al. 2002 M. paucivoransJuvonen and Suihko 2006 M. sueciensisJuvonen and Suihko 2006 M. cerevisiaeEngelmann and Weiss 1986 M. vaginalisSrinivasan et al. 2021 non Bordigoni et al. 2020 M. hutchinsoniSrinivasan et al. 2021 M. lornaeSrinivasan et al. 2021 M. hexanoicaJeon et al. 2017 M. hominisLiu et al. 2022 M. butyricaHitch et al. 2022 M. stantoniiMaki & Looft 2018 M. massiliensisPadmanabhan et al. 2016 M. elsdenii(Gutierrez et al. 1959) Rogosa 1971 M. indicaLanjekar et al. 2014

Megasphaera_C Megasphaera hutchinsoni Megasphaera lornae " Caecibacter " "Megasphaera hominis" "C. massiliensis" Ricaboni et al. 2017 (incl. Megasphaera hexanoica) Megasphaera paucivorans Anaeroglobus Megasphaera vaginalisBordigoni et al. 2020 non Srinivasan et al. 2021 "Colibacter massiliensis" Mailhe et al. 2017 "A. micronuciformis" A. geminatus Megasphaera M. cerevisiae M. stantonii M. massiliensis M. elsdenii

Unassigned species:

• "M. intestinihominis" Hitch et al. 2024

See also

• List of bacterial vaginosis microbiota
• List of bacterial orders
• List of bacteria genera

References

1. A.C. Parte; et al. "Megasphaera". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved 2025-02-28.
2. C.L. Schoch; et al. "Megasphaera". National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved 2025-02-28.
3. Yutin N, Galperin MY (2013) A genomic update on Clostridial phylogeny: Gram-negative spore formers and other misplaced Clostridia. Environ Microbiol doi: 10.1111/1462-2920.12173
4. "The LTP" . Retrieved 10 December 2024.
5. "LTP_all tree in newick format" . Retrieved 10 December 2024.
6. "LTP_10_2024 Release Notes" (PDF). Retrieved 10 December 2024.
7. "GTDB release 09-RS220". Genome Taxonomy Database . Retrieved 10 May 2024.
8. "bac120_r220.sp_labels". Genome Taxonomy Database . Retrieved 10 May 2024.
9. "Taxon History". Genome Taxonomy Database . Retrieved 10 May 2024.

• Arik, H. D., Gulsen, N., Hayirli, A., & Alatas, M. S. (2019). Efficacy of Megasphaera elsdenii inoculation in subacute ruminal acidosis in cattle. Journal of animal physiology and animal nutrition, 103(2), 416–426.