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Lorne Mendell is a neurobiologist currently employed as a distinguished professor in the department of neurobiology and behavior at Stony Brook University in New York. His research focuses primarily on neurotrophins in neonatal and adult mammals, and on the neuroplasticity of the mammalian spinal cord. Mendell's research interests lie in other areas including pain, nerve wind-up, and specifically the neurotrophin, NT-3. His research has contributed findings to the growing pool of knowledge of axonal development and regeneration of immature and mature neurons. Mendell has been a part of the search for novel treatments for spinal cord injuries and continues to study neurotrophins to determine their effects on neuronal plasticity. Mendell served a term as the President for the Society of Neuroscience during the years 1997-1998.
References
- ↑ Nerve+Growth+Factor+Receptor+p75 at the US National Library of Medicine Medical Subject Headings (MeSH)
- ↑ Bibel, M.; Hoppe, E.; Barde, Y. A. (1999). "Biochemical and functional interactions between the neurotrophin receptors TRK and p75NTR". The EMBO Journal. 18 (3): 616–22. doi:10.1093/emboj/18.3.616. PMC 1171154 . PMID 9927421.
- ↑ Becker, E. B.; Howell, J.; Kodama, Y.; Barker, P. A.; Bonni, A. (2004). "Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis". The Journal of Neuroscience. 24 (40): 8762–70. doi:10.1523/JNEUROSCI.2953-04.2004. PMC 6729963 . PMID 15470142.
- ↑ Hamanoue, M.; Middleton, G.; Wyatt, S.; Jaffray, E.; Hay, R. T.; Davies, A. M. (1999). "P75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor". Molecular and Cellular Neurosciences. 14 (1): 28–40. doi:10.1006/mcne.1999.0770. PMID 10433815. S2CID 25648122.
- ↑ Ibáñez C (2002). "Jekyll-Hyde neurotrophins: the story of proNGF". Trends Neurosci. 25 (6): 284–6. doi:10.1016/S0166-2236(02)02169-0. PMID 12086739. S2CID 9449831.