Peptoniphilus

Peptoniphilus
Scientific classification
Domain:	Bacteria
Phylum:	Bacillota
Order:	Tissierellales
Family:	Peptoniphilaceae
Genus:	Peptoniphilus Ezaki et al. 2001 [1]
Type species
Peptoniphilus asaccharolyticus (Distaso 1912) Ezaki et al. 2001
Species
See text
Synonyms
Anaerosphaera Ueki et al. 2009 "Schleiferella" Rajendram et al. 2001

Peptoniphilus is a genus of bacteria in the phylum Bacillota (Bacteria). ^[2]

Etymology

The name Peptoniphilus derives from:Neo-Latin noun peptonum, peptone; Neo-Latin adjective philus from Greek adjective philos (φίλος) meaning friend, loving; Neo-Latin masculine gender noun Peptoniphilus, friend of peptone, referring to the use of peptone as a major energy source. ^[3]

Classification

Peptoniphilus are gram positive anaerobic cocci that were formerly classified in the genus Peptostreptococcus. ^[4] They are non-saccharolytic, use peptone as a major energy source and produce butyrate. ^[4]

Clinical relevance

This genus is part of the vaginal and gut microbiota. ^{[5] [6]} They have been reported to as present in diabetic skin and soft tissue infections, bone and joint infections, surgical site infections, chorioamnionitis and bloodstream infections. ^[6] They are typically found as part of polymicrobial infections but are difficult to recover with usual clinical cultures. They have been increasingly reported with the more widespread use of 16S PCR and MALDI-TOF for identification. ^[4] They are noted to be linked with an impairment of wound-healing in patients with diabetic foot ulcers if present in abundance during the initial infection. ^[7]

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) ^[8] and National Center for Biotechnology Information (NCBI) ^[9]

16S rRNA based LTP_10_2024 [10] [11] [12]

120 marker proteins based GTDB 09-RS220 [13] [14] [15]

Peptoniphilus P. methioninivorax Rooney et al. 2011 P. stercorisuis Johnson et al. 2014 species‑group 2 Anaerosphaera A. aminiphilaUeki et al. 2009 A. multitoleransRettenmaier, Liebl & Zverlov 2019 Peptoniphilus P. equinusJung et al. 2023 P. asaccharolyticus (Distaso 1912) Ezaki et al. 2001 P. indolicus(Christiansen 1934) Ezaki et al. 2001 P. catoniae Patel et al. 2016 P. koenoeneniaeUlger-Toprak et al. 2012 P. duerdenii Ulger-Toprak et al. 2012 P. lacrimalis(Li et al. 1992) Ezaki et al. 2001 "P. obesi" Mishra et al. 2013 P. lacydonensis Beye et al. 2018 P. rhinitidisKim et al. 2021 P. ovalis P. gorbachii Song, Liu & Finegold 2010 P. tyrrelliaeCitron, Tyrrell & Goldstein 2013 P. senegalensis Mishra et al. 2016 P. faecalisRyu et al. 2021 P. porciWylensek et al. 2021 P. harei (Murdoch et al. 1997) Ezaki et al. 2001 P. timonensis Mishra et al. 2015

Peptoniphilus P. duerdenii P. koenoeneniae P. asaccharolyticus P. indolicus "P. obesi" P. catoniae "P. mikwangii" Cho et al. 2015 P. stercorisuis Anaerosphaera aminiphila Anaerosphaera multitolerans P. lacrimalis "P. raoultii" Diop et al. 2016 P. ovalisLi et al. 2022 P. lacydonensis [incl. P. rhinitidis] P. timonensis P. harei "P. vaginalis" Diop et al. 2016 P. faecalis [incl. P. porci] P. senegalensis [incl. P. tyrrelliae] P. gorbachii "P. grossensis" Mishra et al. 2012

Species incertae sedis: ^{[3] [8]}

• "P. duodeni" Maihe et al. 2017
• "P. genitalis" Abou Chacra et al. 2024
• "P. hominis" Hitch et al. 2024 non Huang et al. 2024
• "P. hominis" Huang et al. 2024 non Hitch et al. 2024
• P. ivorii
• "Ca. P. massiliensis" Fenollar et al. 2006
• P. olseniiSong, Liu & Finegold 2010
• "P. phoceensis" Mourembou et al. 2016
• "P. nemausus" Enault et al. 2019
• "P. septimus" Wang et al. 2022
• P. urinimassiliensis ^[16]

See also

• Bacterial taxonomy
• List of bacteria genera
• List of bacterial orders
• List of bacterial vaginosis microbiota
• Microbiology

References

1. Ezaki, T; Kawamura, Y; Li, N; Zhao, L; Shu, S (1 July 2001). "Proposal of the genera Anaerococcus gen. nov., Peptoniphilus gen. nov. and Gallicola gen. nov. for members of the genus Peptostreptococcus". International Journal of Systematic and Evolutionary Microbiology . 51 (4): 1521–1528. doi: 10.1099/00207713-51-4-1521 . PMID   11491354.
2. Classification of Genera MR in LPSN ; Parte, Aidan C.; Sardà Carbasse, Joaquim; Meier-Kolthoff, Jan P.; Reimer, Lorenz C.; Göker, Markus (1 November 2020). "List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ". International Journal of Systematic and Evolutionary Microbiology. 70 (11): 5607–5612. doi: 10.1099/ijsem.0.004332 .
3. Peptoniphilus in LPSN ; Parte, Aidan C.; Sardà Carbasse, Joaquim; Meier-Kolthoff, Jan P.; Reimer, Lorenz C.; Göker, Markus (1 November 2020). "List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ". International Journal of Systematic and Evolutionary Microbiology. 70 (11): 5607–5612. doi: 10.1099/ijsem.0.004332 .
4. Ezaki, T.; Kawamura, Y.; Li, N.; Li, Z. Y.; Zhao, L.; Shu, S. (2001-07-01). "Proposal of the genera Anaerococcus gen. nov., Peptoniphilus gen. nov. and Gallicola gen. nov. for members of the genus Peptostreptococcus". International Journal of Systematic and Evolutionary Microbiology. 51 (Pt 4): 1521–1528. doi: 10.1099/00207713-51-4-1521 . ISSN   1466-5026. PMID   11491354.
5. Clark, Natalie; Tal, Reshef; Sharma, Harsha; Segars, James (2014). "Microbiota and Pelvic Inflammatory Disease". Seminars in Reproductive Medicine. 32 (1): 043–049. doi:10.1055/s-0033-1361822. ISSN   1526-8004. PMC   4148456 . PMID   24390920.
6. Brown, K.; Church, D.; Lynch, T.; Gregson, D. (2014). "Bloodstream infections due to Peptoniphilus spp.: report of 15 cases". Clinical Microbiology and Infection. 20 (11): O857 –O860. doi:10.1111/1469-0691.12657. PMC   4304329 . PMID   24773457.
7. Kyung, R. Min; Galvis, Adriana; Baquerizo Nole, Katherine L.; Sinha, Rohita; Clarke, Jennifer; Kirsner, Robert S.; Ajdic, Dragana (24 January 2020). "Association between baseline abundance of Peptoniphilus, a Gram-positive anaerobic coccus, and wound healing outcomes of DFUs". PLOS One . 15 (1): e0227006. Bibcode:2020PLoSO..1527006M. doi: 10.1371/journal.pone.0227006 . ISSN   1932-6203. OCLC   8597927442. PMC   6980618 . PMID   31978071.
8. A.C. Parte; et al. "Peptoniphilus". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved 2023-09-09.
9. Sayers; et al. "Peptoniphilus". National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved 2023-09-09.
10. "The LTP" . Retrieved 10 December 2024.
11. "LTP_all tree in newick format" . Retrieved 10 December 2024.
12. "LTP_10_2024 Release Notes" (PDF). Retrieved 10 December 2024.
13. "GTDB release 09-RS220". Genome Taxonomy Database . Retrieved 10 May 2024.
14. "bac120_r220.sp_labels". Genome Taxonomy Database . Retrieved 10 May 2024.
15. "Taxon History". Genome Taxonomy Database . Retrieved 10 May 2024.
16. Brahimi, S.; Cadoret, F.; Founier, P.-E.; Moal, V.; Raoult, D. (March 2017). "'Peptoniphilus urinimassiliensis' sp. nov., a new bacterial species isolated from a human urine sample after de novo kidney transplantation". New Microbes and New Infections. 16: 49–50. doi:10.1016/j.nmni.2017.01.001. PMC   5294733 . PMID   28203376. (This paper currently has an expression of concern, see doi:10.1016/j.nmni.2024.101376, PMID   38799976,  Retraction Watch . If this is an intentional citation to a such a paper, please replace {{ expression of concern |...}} with {{ expression of concern |...|intentional=yes}}.)