UDP-sugar diphosphatase

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UDP-sugar diphosphatase
Identifiers
EC no. 3.6.1.45
CAS no. 57127-20-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, an UDP-sugar diphosphatase (EC 3.6.1.45) is an enzyme that catalyzes the chemical reaction

UDP-sugar + H2O UMP + alpha-D-aldose 1-phosphate

Thus, the two substrates of this enzyme are UDP-sugar and H2O, whereas its two products are UMP and alpha-D-aldose 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is UDP-sugar sugarphosphohydrolase. Other names in common use include nucleosidediphosphate-sugar pyrophosphatase, nucleosidediphosphate-sugar diphosphatase, UDP-sugar hydrolase, and UDP-sugar pyrophosphatase.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1HO5, 1HP1, 1HPU, 1OI8, 1OID, and 1OIE.

Related Research Articles

<span class="mw-page-title-main">ADP-ribose diphosphatase</span>

ADP-ribose diphosphatase (EC 3.6.1.13) is an enzyme that catalyzes a hydrolysis reaction in which water nucleophilically attacks ADP-ribose to produce AMP and D-ribose 5-phosphate. Enzyme hydrolysis occurs by the breakage of a phosphoanhydride bond and is dependent on Mg2+ ions that are held in complex by the enzyme.

In enzymology, an ADP-sugar diphosphatase (EC 3.6.1.21) is an enzyme that catalyzes the chemical reaction

In enzymology, an ATP diphosphatase (EC 3.6.1.8) is an enzyme that catalyzes the chemical reaction

In enzymology, a CDP-diacylglycerol diphosphatase (EC 3.6.1.26) is an enzyme that catalyzes the chemical reaction

In enzymology, a CDP-glycerol diphosphatase (EC 3.6.1.16) is an enzyme that catalyzes the chemical reaction

In enzymology, a dCTP diphosphatase (EC 3.6.1.12) is an enzyme that catalyzes the chemical reaction

In enzymology, a dolichyldiphosphatase (EC 3.6.1.43) is an enzyme that catalyzes the chemical reaction

dUTP diphosphatase Enzyme

In Enzymology, a dUTP diphosphatase (EC 3.6.1.23) is an enzyme that catalyzes the chemical reaction

In enzymology, a FAD diphosphatase (EC 3.6.1.18) is an enzyme that catalyzes the chemical reaction

In enzymology, a guanosine-5'-triphosphate,3'-diphosphate diphosphatase (EC 3.6.1.40) is an enzyme that catalyzes the chemical reaction

In enzymology, a guanosine-diphosphatase (EC 3.6.1.42) is an enzyme that catalyzes the chemical reaction

In enzymology, a m7G(5')pppN diphosphatase (EC 3.6.1.30) is an enzyme that catalyzes the chemical reaction

In enzymology, a NAD+ diphosphatase (EC 3.6.1.22) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Nucleoside-diphosphatase</span> Group of proteins having nucleoside-diphosphatase activity

In enzymology, a nucleoside-diphosphatase (EC 3.6.1.6) is an enzyme that catalyzes the chemical reaction

In enzymology, a nucleoside-triphosphate diphosphatase (EC 3.6.1.19) is an enzyme that catalyzes the chemical reaction

In enzymology, a nucleotide diphosphatase (EC 3.6.1.9) is an enzyme that catalyzes the chemical reaction

In enzymology, an oligosaccharide-diphosphodolichol diphosphatase (EC 3.6.1.44) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Phosphoribosyl-ATP diphosphatase</span> Class of enzymes

In enzymology, a phosphoribosyl-ATP diphosphatase (EC 3.6.1.31) is an enzyme that catalyzes the chemical reaction

In enzymology, an undecaprenyl-diphosphatase (EC 3.6.1.27) is an enzyme that catalyzes the chemical reaction

UDP-2,3-diacylglucosamine diphosphatase (EC 3.6.1.54, UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine pyrophosphatase, ybbF (gene), lpxH (gene)) is an enzyme with systematic name UDP-2,3-bis((3R)-3-hydroxymyristoyl)-alpha-D-glucosamine 2,3-bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate phosphohydrolase. This enzyme catalyses the following chemical reaction

References


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