Disease (Lady Gaga song)

Last updated

"Disease"
Lady Gaga - Disease.png
Single by Lady Gaga
from the album Mayhem
ReleasedOctober 25, 2024
Studio Shangri-La (Malibu)
Genre
Length3:49
Label Interscope
Songwriters
Producers
  • Lady Gaga
  • Andrew Watt
  • Cirkut
Lady Gaga singles chronology
"Die with a Smile"
(2024)		"Disease"
(2024)		"Abracadabra"
(2025)
Music video
"Disease" on YouTube

"Disease" is a song by American singer and songwriter Lady Gaga. It was released as the lead single from her studio album Mayhem on October 25, 2024, by Interscope Records. She wrote and produced the track with Andrew Watt and Cirkut, while Michael Polansky provided additional songwriting. "Disease" is an electropop, dark pop, dance-pop, synth-pop, industrial dance, industrial pop, and EDM song with grungy guitars and four-on-the-floor beats. The lyrics explore how love can cure a partner's affliction. "Disease" received acclaim from critics, who praised its production and Gaga's vocal performance. It has received a nomination for Best Pop Solo Performance at the upcoming 68th Annual Grammy Awards.

Contents

The track peaked at number 14 on the Billboard Global 200 and reached the top 20 in the Czech Republic, Greece, Ireland, Latvia, Slovakia, and the United Kingdom. It received certifications in Brazil, Canada, France, and the United Kingdom. The music video for "Disease", directed by Tanu Muino, depicts Gaga facing different versions of herself and trying to control her personified fears. Gaga first performed the track during a Christmas special of Carpool Karaoke in December 2024. She later included it in the set lists of the Mayhem promotional tour (2025) and the Mayhem Ball concert tour (2025–2026).

Background and production

Lady Gaga revealed that she was working on new music on March 28, 2024, stating, "I am writing some of my best music in as long as I can remember". [1] Record producer Cirkut was invited to work with Gaga through Andrew Watt; the three produced the song "Disease", which was conceived "fairly early in the process" of their creative collaboration and subsequently became a pivotal element of their work for her then-upcoming studio album. [2] Cirkut characterized "Disease" as a "very aggressive" track and an "in-your-face introduction to the project." [2] In a social media post, Gaga shared that "Disease" and its music video were inspired by her confrontation with her fears and "inner darkness". [3] [4]

Gaga wrote "Disease" with Watt, Cirkut, and Michael Polansky. Paul Lamalfa recorded the track at Shangri-La Studios in Malibu, California; Marco Sonzini provided additional engineering, while Tyler Harris worked as the assistant engineer. "Disease" was mixed by Serban Ghenea at Mixstar Studios in Virginia Beach, Virginia, and mastered by Randy Merrill at Sterling Sound Studios in Edgewater, New Jersey. Gaga additionally played synthesizer; Watt played synthesizer, drums, bass guitar, electric guitar, and percussion; and Cirkut played synthesizer and keyboards and provided drum and bass programming. Bryce Bordone worked as the assistant mixing engineer, and Marc VanGool served as the studio technician. [5]

Release

Following the release of "Die with a Smile" on August 16, 2024, and while attending the 81st Venice International Film Festival ahead of the premiere of her film Joker: Folie à Deux (2024), Gaga announced that the lead single from her then-upcoming studio album was to be released in October 2024. [6] [7] On October 18, Spotify updated the titles of seven tracks from her discography to spell out the word "disease", hinting at an upcoming single. [8] [9] Three days later, the song's release was confirmed by Universal Music Group through a pre-save website, which depicted a glitch of the phrase "I could play the doctor" against a black screen. [10] [11] Via her social media, Gaga revealed the official logo of "Disease", a promotional poster, and the release time for cities globally. [12] On October 25, Interscope Records released "Disease" worldwide digitally for download and streaming, [13] and Universal sent it to Italian radio airplay. [14] Four days later, Interscope released it in the United States to contemporary hit radio. [15] Gaga unveiled the track listing of her studio album Mayhem on February 18, 2025, with "Disease" appearing as the album's opening track. [16]

Alternative versions

Gaga released two self-produced live versions of "Disease", one performed on piano and the other on electric guitar. [17] [18] On November 13, 2024, a live version subtitled "The Antidote Live" was released worldwide digitally by Interscope and to Italian radio airplay by Universal. [19] [20] Another live version, subtitled "The Poison Live", was released digitally on November 20 by Interscope. [21] They were both accompanied by visual videos and instrumental versions. [22] [19] [21] Filmed at Woodshed Studios in Malibu, California, the video for "The Antidote Live" version features Gaga performing a stripped-down rendition of "Disease" on a black grand piano with acoustic guitar accompaniment and a backing track. [23] Gaga stated that this version was "really delicate and almost somber" because the song's refrain was originally written on piano. [18] In the video for "The Poison Live" version, she performs an electric guitar rendition with assistance from guitarist Tim Stewart. [24] [18] Gaga stated, "With the electric guitar, there's a sense of fun that I found in the torture of the lyrics, and some of Tim's choices with the chord inversions gave it a sense of 'hurt', and I thought that was really interesting". [18]

Composition

"Disease" is 3 minutes and 49 seconds long. [13] Music journalists identified it as an electropop, [25] dark pop, [26] dance-pop, [27] synth-pop, [28] industrial dance, [29] industrial pop, [30] and EDM song, [31] with gothic, industrial rock, rock, rage, and punk influences. [32] [33] [34] It features an upbeat arrangement, [25] a midtempo rhythm, [35] grungy guitars, [36] and industrial, EDM, and techno-heavy four-on-the-floor beats. [36] [37] Gaga sings with growling vocals in the refrain and uses her falsetto register in the bridge. [26] [34] Several critics compared the song's heavy electronic and industrial production to the music of Nine Inch Nails. [34] [30] [38] [39] Roisin O'Connor from The Independent thought that Gaga's vocals and the "squelching" synth line evoked George Michael's single "Freeek!" (2002). [36]

Several journalists found "Disease" similar to Gaga's singles "Bad Romance" (2009) and "The Cure" (2017)". [a] Alexis Petridis of The Guardian particularly compared her "strident, imperious" vocals to those of "The Cure" and "Poker Face" (2008). [37] He compared the track to Gaga's album The Fame (2008), while Alexa Camp from Slant Magazine likened its composition to The Fame Monster (2009) and Born This Way (2011). [31] [37]

Gaga said that "Disease" served as an entry point "into the chaos of the album", symbolizing uncomfortable emotions and negative internal dialogues. [41] The lyrics explore love's ability to heal a partner's deep affliction [26] [25] [42] and "seeing the vulnerabilities of being in a dark place ... and how this can lead to self-nurturing and coexistence". [43] Gaga sings in the refrain, "I could play the doctor, I can cure your disease / If you were a sinner, I could make you believe / Lay you down like one, two, three / Eyes roll back in ecstasy". [44] Nick Levine of the BBC dubbed the lyrics "melodramatic" and wrote that the song was a "welcome reminder that she stormed the mainstream by making music that was catchy and freaky in equal measure." [42]

Critical reception

"Disease" ratings
Review scores
SourceRating
Clash 9/10 [34]
Evening Standard Star full.svgStar full.svgStar full.svgStar full.svgStar full.svg [45]
The Guardian Star full.svgStar full.svgStar full.svgStar full.svgStar empty.svg [37]
The Independent Star full.svgStar full.svgStar full.svgStar full.svgStar empty.svg [36]

"Disease" received acclaim from critics, [46] [47] who praised its production [37] [31] and Gaga's vocal performance. [45] [48] Journalists from Consequence named it the "Song of the Week" upon its release, describing it as a "four minute reminder that pop music is where so many elements of performance have the opportunity to coalesce." [49] Robin Murray of Clash dubbed it as "lustful, salacious, and industrial" and considered the chorus one of her best choruses. [34] Evening Standard 's India Block praised the production, religious themes, and Gaga's vocals, deeming the track a "high gothic blast that's perfect for spooky season". [45] Paste 's Sam Rosenberg wrote that "Disease" was an "exciting, promising" introduction to Mayhem's thematic exploration of chaos, adding that its dark nature was engaging enough to keep the album's energy flowing. [50] Helen Brown from The Independent praised Gaga's vocal performance and the song's "compellingly wonky pace". [48] Beats Per Minute 's JT Early wrote that the contrast between the song's "empowering" message and "clanging" production highlighted "darkness as a constant thing to overcome". [43] Camp and O'Connor described the lyrics as "cliché" but praised the sound and production; the latter said that "Disease" was "her best in a long while". [31] [36]

Billboard's Stephen Daw placed "Disease" at number nine in a ranking of Mayhem's fourteen tracks, describing it as a "delirious pop banger". [51] The song featured on 2024 year-end lists by Rolling Stone (17th) [52] and The Guardian (18th). [53] Brittany Spanos from the former publication called it a "thrilling and very welcome return to form" and a "sick and ferocious reminder that Gaga is one of one". [52] Marcus Wratten of PinkNews placed it at number four in a ranking of Gaga's seven lead singles, deeming it "her most macabre lead offering since 2009's 'Bad Romance'". [54] "Disease" appeared in rankings of Gaga's discography by Vulture 's Kristen S. Hé (16 out of 170) [55] and The Independent's Adam White (30 out of 123). [38]

Commercial performance

"Disease" reached number 14 on the Billboard Global 200 chart dated November 9, 2024. [56] In the United States, the track peaked at number 5 on the Hot Dance/Pop Songs chart, [57] number 16 on the Adult Pop Airplay chart, [58] number 17 on the Pop Airplay chart, [59] and number 27 on the Billboard Hot 100 chart. [60] In the United Kingdom, "Disease" debuted at number seven on the UK Singles Chart, marking the sixteenth top-ten song in Gaga's career. [61] "Disease" additionally reached the top 30 on the charts of Greece (6), [62] the Czech Republic (10), [63] Ireland (11), [64] Latvia (14), [65] Slovakia (20), [66] Brazil (21), [67] the Netherlands (25), [68] Portugal (25), [69] Lithuania (26), [70] Switzerland (27), [71] and Canada (28). [72] The track was certified double platinum in Brazil, [73] platinum in Canada, [74] gold in France, [75] and silver in the United Kingdom. [76]

Music video

Gaga in the music video, embracing a macabre version of herself with a gothic look and long fingernails, which was compared to the film Edward Scissorhands (1990). Lady Gaga - Disease (music video screenshot).jpg
Gaga in the music video, embracing a macabre version of herself with a gothic look and long fingernails, which was compared to the film Edward Scissorhands (1990).

Gaga shared a snippet from the music video for "Disease" on her social media on October 22, 2024. It depicts her wearing a white dress and running from a car driving towards her on a suburban street; she turns back to the mystery driver several times throughout the video as she tries to escape. [12] [78] Vulture's Jason P. Frank compared the dress in the video to that of Samara Morgan from the 2002 psychological horror film The Ring . [79] The music video for "Disease" was released on October 29. [80]

Directed by Tanu Muino and choreographed by Parris Goebel, [81] [4] the four-and-a-half-minute video takes place in a quiet suburban neighborhood and depicts Gaga facing different versions of herself and trying to regain control of her personified fears. [82] [83] One of the versions features a red-eyed version of Gaga wearing an all-black leather outfit, a zippered mask, and long fingernails studded with steel. [82] [84] She runs over a "more innocent" version wearing a nightgown with a floral print. [85] A version of Gaga wearing white crop top and briefs walks over her clone while being handcuffed to the ceiling, [3] [85] and another version wearing an ombré mesh dress with dip dye appears in a dark vomit pool before being trapped between two colliding walls. [85] [77] Throughout the video, the different versions of Gaga are seen either engaging in fights, running down the street, dancing, or embracing each other. [84]

Reception

The music video received praise from fans and critics. [86] Gonzales deemed the video "haunting and at times disturbing", [3] and Attitude 's Jamie Tabberer dubbed it "dark, twisted, and deeply personal" and compared it to horror films. [87] Christian Allaire from Vogue and Gonzales praised the video's theme and avant-garde fashion costumes. [3] [85] Uproxx 's Flisadam Pointer commended the production, elaborate wardrobe changes, and Gaga's performance. [88] Matthew Velasco from the magazine W dubbed the video "cinematic" and said that it has "almost theater-like experience". He found the video's theme reminiscent of The Fame Monster era and the music videos for Gaga's singles "Bad Romance" and "Alejandro" (2010). [89] Nylon 's Dylan Kickham similarly compared the video's horror-leaning artistic direction to Gaga's previous works. [90] Danielle Chelosky from Stereogum thought that the video evoked the gothic film Edward Scissorhands (1990), particularly due to the character dressed in all black with long fingernails. [77]

Live performances and cover versions

Gaga performing "Disease" at the Mayhem Ball in 2025 Lady Gaga performs Disease at The Mayhem Ball in Los Angeles (cropped).jpg
Gaga performing "Disease" at the Mayhem Ball in 2025

Gaga first performed "Disease" during a Christmas special of the television series Carpool Karaoke , which premiered on December 15, 2024, on Apple Music and Apple TV+. [91] She later included the track in the set list of the Mayhem promotional tour in 2025 [92] and reprised the performance at the Mayhem Ball concert tour (2025–2026). [93] During the performance, Gaga, dressed in a white gown and platinum blonde hair, fights several skull-faced dancers and a red-dressed doppelgänger; [94] [95] [96] they fight in a sand-filled grave before Gaga is ultimately strangled. [92] [94] Adrian Horton of The Guardian picked the performance as the highlight of the show, stating that it left her "agape". [92] Livia Caligor from the magazine W wrote that the performance revisited the "Gothic dreamscape of [Gaga's] past" and thought that the skeletal dancers represented her "inner demons". [95] Wesley Morris from The New York Times Magazine commended how "in spite of all the tussling and writhing, she didn't miss a note." [97]

In November 2024, English singer Cassyette shared a video singing a screamcore rendition of "Disease", to which Gaga reacted favorably. [98] [99] The full cover version was released to digital music platforms on December 7, 2024. [100] In October 2025, American singer Demi Lovato performed a mashup of "Disease" and the Mayhem track "Perfect Celebrity" on BBC Radio 1's Live Lounge, joined by a backup band. The cover of "Disease" featured a slight rock edge compared to the original version. [101]

Accolades

Awards and nominations for "Disease"
OrganizationYearCategoryResultRef.
MTV Video Music Awards Japan 2025 Video of the Year Nominated [102]
Best Solo Artist Video – InternationalWon [103]
Grammy Awards 2026 Best Pop Solo Performance Pending [104]

Credits and personnel

Credits are adapted from the liner notes of Mayhem. [5]

Charts

Certifications

Certifications for "Disease"
RegionCertification Certified units/sales
Brazil (Pro-Música Brasil) [73] 2× Platinum80,000‡
Canada (Music Canada) [74] Platinum80,000‡
France (SNEP) [75] Gold100,000‡
United Kingdom (BPI) [76] Silver200,000‡

‡ Sales+streaming figures based on certification alone.

Release history

"Disease" release history
RegionDateFormat(s)Version(s)LabelRef.
VariousOctober 25, 2024Original Interscope [13]
Italy Radio airplay Universal [14]
United StatesOctober 29, 2024 Contemporary hit radio Interscope [15]
VariousNovember 13, 2024
  • Digital download
  • streaming
  • The Antidote Live
  • The Antidote Live Instrumental
 [19]
ItalyRadio airplayThe Antidote LiveUniversal [20]
VariousNovember 20, 2024
  • Digital download
  • streaming
  • The Poison Live
  • The Poison Live Instrumental
Interscope [21]

Footnote

  1. ↑ Attributed to multiple references: [26] [31] [32] [35] [37] [40]

References

  1. ↑ Guglielmi, Jodi (July 19, 2024). "Lady Gaga Returns to the Studio for LG7: 'Happy as Ever Making Music'" . Rolling Stone . Archived from the original on September 26, 2024. Retrieved October 21, 2024.
  2. 1 2 Daw, Stephen (November 21, 2024). "How Cirkut's Vision for the Future of Pop Boosted Lady Gaga & ROSÉ's Latest Hot 100 Hits". Billboard . Archived from the original on November 21, 2024. Retrieved November 21, 2024.
  3. 1 2 3 4 Gonzales, Erica (October 29, 2024). "Lady Gaga's 'Disease' Music Video Is Downright Haunting". Elle . Archived from the original on November 9, 2024. Retrieved October 30, 2024.
  4. 1 2 Green, Walden (October 29, 2024). "Watch Lady Gaga's New "Disease" Video". Pitchfork . Archived from the original on October 31, 2024. Retrieved October 30, 2024.
  5. 1 2 Gaga, Lady (2025). Mayhem (vinyl liner notes). Interscope Records. 602475451099.
  6. ↑ Aswad, Jem (September 3, 2024). "Lady Gaga to Drop First Single From New Album in October". Variety . Archived from the original on October 7, 2024. Retrieved October 26, 2024.
  7. ↑ Daw, Stephen (September 3, 2024). "Lady Gaga Confirms Her First Single Off LG7 Will Arrive in October". Billboard . Archived from the original on December 8, 2024. Retrieved October 21, 2024.
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