Fastigial nucleus

Last updated
Fastigial nucleus
Sobo 1909 658.png
Cross-section of the cerebellum. Fastigial nucleus labeled at top-right.
Details
Identifiers
Latin nucleus fastigii
NeuroNames 690
NeuroLex ID birnlex_1146
TA98 A14.1.07.411
TA2 5840
FMA 72537
Anatomical terms of neuroanatomy

The fastigial nucleus (roof nucleus-1) is located in each cerebellar hemisphere. It is one of the four paired deep cerebellar nuclei of the cerebellum.

Contents

It is made up of two sections: the rostral fastigial nucleus and the caudal fastigial nucleus.

Anatomy

The fastigial nuclei is situated atop the roof of the fourth ventricle (thence its name: "fastigus" is Latin for "summit"). [1]

The fastigial nucleus is a mass of gray matter nearest to the middle line at the anterior end of the superior vermis, immediately over the roof of the fourth ventricle (the peak of which is called the fastigium), from which it is separated by a thin layer of white matter. [2]

It is smaller than the dentate nucleus, but somewhat larger than the emboliform nucleus and globose nucleus.[ citation needed ]

Afferents

The fastigial nucleus receives afferents from the vestibulocerebellar tract (containing first-order axons from the vestibular nerve as well as second-order axons from the vestibular nuclei), and from Purkinje cells of the vestibulocerebellum cortex. [1]

Efferents

The fastigial nucleus projects efferents to: the medial, lateral and inferior vestibular nuclei, reticular formation, ventral lateral nucleus of thalamus, and cerebellar cortex. It gives rise to fastigiovestibular fibres, and fastigioreticular fibres: both leave the cerebellum via the juxtarestiform body of the inferior cerebellar peduncle. [1]

Through the vestibulospinal and reticulospinal tracts, the fastigial efferents are involved in regulation of balance and posture as well as axial and proximal limb musculature activity. [1]

Structure

Rostral fastigial nucleus

The rostral fastigial nucleus (rFN) is related to the vestibular system. It receives input from the vestibular nuclei and contributes to vestibular neuronal activity. The rFN interprets body motion and places it on spatial planes to estimate the movement of the body through space. [3] It deals with antigravity muscle groups and other synergies involved with standing and walking. [4]

Caudal fastigial nucleus

The caudal fastigial nucleus (cFN) is related to saccadic eye movements. The Purkinje cell output from the oculomotor vermis relays through the cFN, where neurons directly related to saccadic eye movements are located. [5]

Related Research Articles

<span class="mw-page-title-main">Medulla oblongata</span> Structure of the brain stem

The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involuntary) functions, ranging from vomiting to sneezing. The medulla contains the cardiovascular center, the respiratory center, vomiting and vasomotor centers, responsible for the autonomic functions of breathing, heart rate and blood pressure as well as the sleep–wake cycle. "Medulla" is from Latin, ‘pith or marrow’. And "oblongata" is from Latin, ‘lengthened or longish or elongated'.

Articles related to anatomy include:

<span class="mw-page-title-main">Brainstem</span> Posterior part of the brain, adjoining and structurally continuous

The brainstem is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem.

<span class="mw-page-title-main">Midbrain</span> Forward-most portion of the brainstem

The midbrain or mesencephalon is the uppermost portion of the brainstem connecting the diencephalon and cerebrum with the pons. It consists of the cerebral peduncles, tegmentum, and tectum.

<span class="mw-page-title-main">Cerebellar vermis</span> Structure connecting the two cerebellar hemispheres

The cerebellar vermis is located in the medial, cortico-nuclear zone of the cerebellum, which is in the posterior fossa of the cranium. The primary fissure in the vermis curves ventrolaterally to the superior surface of the cerebellum, dividing it into anterior and posterior lobes. Functionally, the vermis is associated with bodily posture and locomotion. The vermis is included within the spinocerebellum and receives somatic sensory input from the head and proximal body parts via ascending spinal pathways.

<span class="mw-page-title-main">Pontine nuclei</span> Parts of the mammalian brain

The pontine nuclei are all the neurons of the ventral pons. Corticopontine fibres project from the primary motor cortex to the ipsilateral pontine nucleus; pontocerebellar fibers then relay the information to the contralateral cerebellum via the middle cerebellar peduncle.

<span class="mw-page-title-main">Spinocerebellar tracts</span> Nerve tract in humans

The spinocerebellar tracts are nerve tracts originating in the spinal cord and terminating in the same side (ipsilateral) of the cerebellum. The two main tracts are the dorsal spinocerebellar tract, and the ventral spinocerebellar tract. Both of these tracts are located in the peripheral region of the lateral funiculi. Other tracts are the rostral spinocerebellar tract, and the cuneocerebellar tract.

<span class="mw-page-title-main">Deep cerebellar nuclei</span>

There are four paired deep cerebellar nuclei embedded in the white matter centre of the cerebellum. The nuclei are the fastigial, globose, emboliform, and dentate nuclei.

<span class="mw-page-title-main">Inferior cerebellar peduncle</span>

The inferior cerebellar peduncle is formed by fibers of the restiform body that join with fibers from the much smaller juxtarestiform body. The inferior cerebellar peduncle is the smallest of the three cerebellar peduncles.

<span class="mw-page-title-main">Dentate nucleus</span> Nucleus in the centre of each cerebellar hemisphere

The dentate nucleus is a cluster of neurons, or nerve cells, in the central nervous system that has a dentate – tooth-like or serrated – edge. It is located within the deep white matter of each cerebellar hemisphere, and it is the largest single structure linking the cerebellum to the rest of the brain. It is the largest and most lateral, or farthest from the midline, of the four pairs of deep cerebellar nuclei, the others being the globose and emboliform nuclei, which together are referred to as the interposed nucleus, and the fastigial nucleus.

<span class="mw-page-title-main">Globose nucleus</span> Part of the interposed nucleus, a structure in the cerebellum.

The globose nucleus is one of the deep cerebellar nuclei. It is located medial to the emboliform nucleus, and lateral to the fastigial nucleus. The globose nucleus and emboliform nucleus are known collectively as the interposed nuclei.

<span class="mw-page-title-main">Flocculonodular lobe</span> Lobe of the cerebellum

The flocculonodular lobe (vestibulocerebellum) is one of the lobes of the cerebellum. It is a small lobe consisting of the unpaired midline nodule and the two flocculi: one flocculus on either side of the nodule. The lobe is involved in maintaining posture and balance as well as coordinating head-eye movements.

<span class="mw-page-title-main">Flocculus</span>

The flocculus is a small lobe of the cerebellum at the posterior border of the middle cerebellar peduncle anterior to the biventer lobule. Like other parts of the cerebellum, the flocculus is involved in motor control. It is an essential part of the vestibulo-ocular reflex, and aids in the learning of basic motor skills in the brain.

<span class="mw-page-title-main">Vestibular nuclei</span>

The vestibular nuclei (VN) are the cranial nuclei for the vestibular nerve located in the brainstem.

<span class="mw-page-title-main">Cerebellar peduncles</span> Structure connecting the cerebellum to the brainstem

The cerebellar peduncles are three paired bundles of fibres that connect the cerebellum to the brain stem.

<span class="mw-page-title-main">Lateral vestibular nucleus</span>

The lateral vestibular nucleus is the continuation upward and lateralward of the principal nucleus, and in it terminate many of the ascending branches of the vestibular nerve.

The reticulotegmental nucleus, tegmental pontine reticular nucleus is an area within the floor of the pons, in the brain stem. This area is known to affect the cerebellum with its axonal projections.

<span class="mw-page-title-main">Juxtarestiform body</span> Subdivision of the Inferior Cerebellar Penduncle

The juxtarestiform body is the smaller, medial subdivision of each inferior cerebellar peduncle.

<span class="mw-page-title-main">Anatomy of the cerebellum</span> Structures in the cerebellum, a part of the brain

The Anatomy of the Cerebellum can be viewed at three levels. At the level of gross anatomy, the cerebellum consists of a tightly folded and crumpled layer of cortex, with white matter underneath, several deep nuclei embedded in the white matter, and a fluid-filled ventricle in the middle. At the intermediate level, the cerebellum and its auxiliary structures can be broken down into several hundred or thousand independently functioning modules or compartments known as microzones. At the microscopic level, each module consists of the same small set of neuronal elements, laid out with a highly stereotyped geometry.

References

PD-icon.svgThis article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

  1. 1 2 3 4 5 6 Patestas, Maria A.; Gartner, Leslie P. (2016). A Textbook of Neuroanatomy (2nd ed.). Hoboken, New Jersey: Wiley-Blackwell. pp. 291–292. ISBN   978-1-118-67746-9.
  2. John K. Harting (1997). "The Global Cerebellum '97". University of Wisconsin Medical School. Retrieved 2007-06-28.
  3. Brooks & Cullen, <http://www.jneurosci.org/content/29/34/10499.full.pdf> [Multimodal integration in rostral fastigial nucleus provides an estimate of body movement], 2009
  4. James D. Geyer; Janice M. Keating; Daniel C. Potts (1998). Neurology for the Boards. Philadelphia: Lippincott-Raven. p. 9.
  5. Kleine, Guan, & Buttner, <http://jn.physiology.org/content/90/5/3137.full.pdf+html> [Saccade-related neurons in the primate fastigial nucleus: what do they encode?], 2003