Glycerophosphocholine cholinephosphodiesterase

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glycerophosphocholine cholinephosphodiesterase
Identifiers
EC no. 3.1.4.38
CAS no. 60063-78-7
Databases
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BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
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Gene Ontology AmiGO / QuickGO
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NCBI proteins

The enzyme glycerophosphocholine cholinephosphodiesterase (EC 3.1.4.38) is an enzyme that catalyzes the reaction

sn-glycero-3-phosphocholine + H2O = glycerol + phosphocholine

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is sn-glycero-3-phosphocholine cholinephosphohydrolase. This enzyme is also called L-3-glycerylphosphinicocholine cholinephosphohydrolase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1WRA.

Related Research Articles

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<span class="mw-page-title-main">Diacylglycerol cholinephosphotransferase</span>

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<span class="mw-page-title-main">1-Lysophosphatidylcholine</span>

2-acyl-sn-glycero-3-phosphocholines are a class of phospholipids that are intermediates in the metabolism of lipids. Because they result from the hydrolysis of an acyl group from the sn-1 position of phosphatidylcholine, they are also called 1-lysophosphatidylcholine. The synthesis of phosphatidylcholines with specific fatty acids occurs through the synthesis of 1-lysoPC. The formation of various other lipids generates 1-lysoPC as a by-product.

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References