Arylsulfatase

Last updated
Arylsulfatase
4cxs.jpg
Arylsulfatase monomer, Pseudomonas aeruginosa
Identifiers
EC no. 3.1.6.1
CAS no. 9016-17-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

Arylsulfatase (EC 3.1.6.1, sulfatase, nitrocatechol sulfatase, phenolsulfatase, phenylsulfatase, p-nitrophenyl sulfatase, arylsulfohydrolase, 4-methylumbelliferyl sulfatase, estrogen sulfatase) is a type of sulfatase enzyme with systematic name aryl-sulfate sulfohydrolase. [1] [2] [3] [4] This enzyme catalyses the following chemical reaction

an aryl sulfate + H2O a phenol + sulfate

It catalyses an analogous reaction for sulfonated hexoses. Types include:

See also

References

  1. Dodgson KS, Spencer B, Williams K (October 1956). "Studies on sulphatases. 13. The hydrolysis of substituted phenyl sulphates by the arylsulphatase of Alcaligenes metalcaligenes". The Biochemical Journal. 64 (2): 216–21. doi:10.1042/bj0640216. PMC   1199721 . PMID   13363831.
  2. Roy AB (1960). "The synthesis and hydrolysis of sulfate esters". Advances in Enzymology and Related Areas of Molecular Biology. Vol. 22. pp. 205–35. doi:10.1002/9780470122679.ch5. PMID   13744184.{{cite book}}: |journal= ignored (help)
  3. Roy AB (April 1976). "Sulphatases, lysosomes and disease". The Australian Journal of Experimental Biology and Medical Science. 54 (2): 111–35. doi:10.1038/icb.1976.13. PMID   13772.
  4. Webb EC, Morrow PF (September 1959). "The activation of an arysulphatase from ox liver by chloride and other anions". The Biochemical Journal. 73 (1): 7–15. doi:10.1042/bj0730007. PMC   1197004 . PMID   13843260.