Magnesium glycinate

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Magnesium glycinate
Magnesium diglycinate.svg
Names
IUPAC name
Magnesium diglycinate
Systematic IUPAC name
Magnesium bis(aminoacetate)
Identifiers
3D model (JSmol)
ChemSpider
DrugBank
ECHA InfoCard 100.035.305 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 238-852-2
PubChem CID
UNII
  • InChI=1S/2C2H5NO2.Mg/c2*3-1-2(4)5;/h2*1,3H2,(H,4,5);/q;;+2/p-2
    Key: AACACXATQSKRQG-UHFFFAOYSA-L
  • C(C(=O)[O-])N.C(C(=O)[O-])N.[Mg+2]
Properties
C4H8MgN2O4
Molar mass 172.423 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Magnesium glycinate, also known as magnesium diglycinate or magnesium bisglycinate, is the magnesium salt of glycinate. The structure and even the formula has not been reported. The compound is sold as a dietary supplement. [1] [2] It contains 14.1% elemental magnesium by mass.

Contents

Magnesium glycinate is also often "buffered" with magnesium oxide but it is also available in its pure non-buffered magnesium glycinate [3] form.

Uses

Magnesium glycinate has been studied with applicability to patients with a bowel resection [1] or pregnancy-induced leg cramps. [2] Less scientific research exists on magnesium glycinate in therapeutic applications than other more common forms of magnesium salt such as magnesium chloride, oxide or citrate.

A 2013 systematic review suggested that higher dietary magnesium intake may be linked to reduced depression symptoms and that magnesium supplementation could help treat or prevent depression. [4]

Magnesium deficiency is one of most common mineral deficiencies in people today. Many people consume less than the recommended amount by experts but the symptoms of low magnesium intake are not always noticeable.[ citation needed ]

A kind of magnesium supplement sold in Australia, containing magnesium glycinate, glycine and extracts from Passiflora incarnata Magnesium glycinate supplement Australia.jpg
A kind of magnesium supplement sold in Australia, containing magnesium glycinate, glycine and extracts from Passiflora incarnata

Chemical structure

According to X-ray crystallography, magnesium glycinate may exist in several forms, often with other anions. [5]

See also

References

  1. 1 2 Schuette SA, Lashner BA, Janghorbani M (1994). "Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection". Journal of Parenteral and Enteral Nutrition. 18 (5): 430–5. doi:10.1177/0148607194018005430. PMID   7815675. Magnesium diglycinate may be a good alternative to commonly used magnesium supplements in patients with intestinal resection.
  2. 1 2 Supakatisant C, Phupong V (2015). "Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial". Maternal & Child Nutrition. 11 (2): 139–45. doi:10.1111/j.1740-8709.2012.00440.x. PMC   6860204 . PMID   22909270. Forty-one women were assigned to magnesium bisglycinate chelate (300 mg per day) and 39 women to placebo. Details of leg cramps were recorded before beginning the treatment and the fourth week of study.
  3. ↑ "Magnesium Bisglycinate". 88Herbs. 20 November 2014.
  4. ↑ Derom ML, Sayón-Orea C, Martínez-Ortega JM, Martínez-González MA (1 September 2013). "Magnesium and depression: a systematic review" . Nutritional Neuroscience. 16 (5): 191–206. doi:10.1179/1476830512Y.0000000044. ISSN   1028-415X. PMID   23321048.
  5. ↑ Clulow R, Lightfoot P (2018). "New sarcosine–metal halide complexes related to ferroelectric TSCC". CrystEngComm. 20 (28): 4012–4019. Bibcode:2018CEG....20.4012C. doi:10.1039/C8CE00719E.
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