Star anise | |
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Illicium verum at the United States National Arboretum | |
Star anise fruits and seeds | |
Scientific classification | |
Kingdom: | Plantae |
Clade: | Tracheophytes |
Clade: | Angiosperms |
Order: | Austrobaileyales |
Family: | Schisandraceae |
Genus: | Illicium |
Species: | I. verum |
Binomial name | |
Illicium verum | |
Synonyms [1] | |
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Illicium verum (star anise or badian, Chinese star anise, star anise seed, star aniseed and star of anise) is a medium-sized evergreen tree native to South China and northeast Vietnam. Its star-shaped pericarps harvested just before ripening is a spice that closely resembles anise in flavor. Its primary production country is China, followed by Vietnam and other Southeast Asian countries. [2] Star anise oil is a highly fragrant oil used in cooking, perfumery, soaps, toothpastes, mouthwashes, and skin creams. Until 2012, when they switched to using genetically modified E. coli , Roche Pharmaceuticals used up to 90% of the world's annual star anise crop to produce oseltamivir (Tamiflu) via shikimic acid. [3]
Star anise | |||||||||||||||||||
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Chinese | 八角 | ||||||||||||||||||
Literal meaning | "eight-horns" | ||||||||||||||||||
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Illicium comes from the Latin illicio meaning "entice" or "seduce". [4]
Verum means "true" or "genuine". [4]
The name "badian" appears to derive,via French badiane,from the apparently descriptive Chinese name for it,八角,pinyin :bājiǎo,lit. "eight horns". However,a derivation from the Persian بادیان bādiyān, "fennel",exists,with the Oxford English Dictionary indicating that its origin before that is unknown. [5]
Leaves are aromatic,simple and lanceolate,obovate-elliptic or elliptic,size of 5–15 cm ×2–5 cm,coriaceous to thickly coriaceous. [6] The leaves are 5–15 cm ×1.5–5 cm,apex acute,lower side pubescent. [6] Flowers are solitary,bisexual,pink to dark red,axillary or subterminal. [6] The perianth has lobes 7–12,arranged spirally;stamens number of 11–20,arranged spirally,with short,thick filaments;carpels usually 8,free,arranged in a single whorl. Flower peduncle size is 1.5–4 cm,tepals number range from seven to twelve,and are broadly elliptic to broadly ovate,anthers size is 1–1.5 mm,pollen grains trisyncolpate. [6] [7]
The fruit is a capsule-like follicetum,star-shaped,reddish-brown,consisting of six to eight follicles arranged in a whorl. [6] Each follicle is boat-shaped,1–2 cm long,rough and rigid,color reddish-brown,with 1 seed,opening along the ventral edge when ripe. [6] carpels size of 10 mm long,boat-shaped;they are hard and wrinkled,containing one seed. Seeds are brown,compressed ovoid,smooth,shiny and brittle with approximate size of 8–9 mm ×6 mm. [6] [7]
Differences with similar taxa:Illicium anisatum had smaller fruits that does not form a regular star due to the abortion of some carpels. Also fruit follicles are not swollen in the middle and had a more pointed apex. Also usually had more than 8 follicles and the fruit has weaker odour. The seeds in Illicium anisatum are flat or almost spherical. [6] [7]
Star anise contains anethole,the same compound that gives anise,an unrelated plant,its flavor. Star anise has come into use in the West as a less expensive substitute for anise in baking,as well as in liquor production,most distinctively in the production of the liqueur Galliano. [8] Star anise enhances the flavor of meat. [9]
It is used as a spice in preparation of biryani and masala chai all over the Indian subcontinent. It is widely used in Chinese cuisine,and in Malay and Indonesian cuisines. It is widely grown for commercial use in China,India,and most other countries in Asia. Star anise is an ingredient of the traditional five-spice powder of Chinese cooking. It is also a major ingredient in the making of phở ,a Vietnamese noodle soup.
It is also used in the French recipe of mulled wine, vin chaud (hot wine). If allowed to steep in coffee,it deepens and enriches the flavor. The pods can be used in this manner multiple times by the potful or cup,as the ease of extraction of the taste components increases with the permeation of hot water.
Star anise is the major source of the chemical compound shikimic acid,a primary precursor in the pharmaceutical synthesis of the anti-influenza drug oseltamivir (Tamiflu). [10] [11] [12] An industrial method for the production of shikimic acid using fermentation of E. coli bacteria was discovered in 2005, [13] [14] and applied in the 2009 swine flu pandemic to address Tamiflu shortages,eventually reversing price increases for star anise as a raw material of shikimic acid. [15] As of 2018,fermentation of E. coli was the manufacturing process of choice to produce shikimic acid for synthesis of Tamiflu. [10] [11]
Illicium verum is not toxic. However,other related species are toxic.
Japanese star anise (Illicium anisatum),a similar tree,is highly toxic and inedible;in Japan,it has instead been burned as incense. Cases of illness,including "serious neurological effects,such as seizures",reported after using star anise tea may be a result of deliberate economically motivated adulteration with this species. Japanese star anise contains the neurotoxin anisatin, [16] which also causes severe inflammation of the kidneys (nephritis),urinary tract,and digestive organs when ingested. [17]
Swamp star anise Illicium parviflorum ,a similar tree found in the southern United States,is highly toxic and should not be used for folk remedies or as a cooking ingredient. [18]
Joshi et al. have used fluorescent microscopy and gas chromatography [20] to distinguish the species,while Lederer et al. employed thin layer chromatography with HPLC-MS/MS. [21]
Five-spice powder is a spice mixture of five or more spices—commonly star anise,cloves,Chinese cinnamon,Sichuan pepper,and fennel seeds—used predominantly in almost all branches of Chinese cuisine. The five flavors of the spices refers to the five traditional Chinese elements. The addition of eight other spices creates thirteen-spice powder (十三香),which is used less commonly.
Tarragon,also known as estragon,is a species of perennial herb in the family Asteraceae. It is widespread in the wild across much of Eurasia and North America and is cultivated for culinary and medicinal purposes.
Anise,also called aniseed or rarely anix,is a flowering plant in the family Apiaceae native to the eastern Mediterranean region and Southwest Asia.
Fennel is a flowering plant species in the carrot family. It is a hardy,perennial herb with yellow flowers and feathery leaves. It is indigenous to the shores of the Mediterranean but has become widely naturalized in many parts of the world,especially on dry soils near the sea coast and on riverbanks.
Oseltamivir,sold under the brand name Tamiflu among others,is an antiviral medication used to treat and prevent influenza A and influenza B,viruses that cause the flu. Many medical organizations recommend it in people who have complications or are at high risk of complications within 48 hours of first symptoms of infection. They recommend it to prevent infection in those at high risk,but not the general population. The Centers for Disease Control and Prevention (CDC) recommends that clinicians use their discretion to treat those at lower risk who present within 48 hours of first symptoms of infection. It is taken by mouth,either as a pill or liquid.
Anethole is an organic compound that is widely used as a flavoring substance. It is a derivative of the aromatic compound allylbenzene and occurs widely in the essential oils of plants. It is in the class of phenylpropanoid organic compounds. It contributes a large component of the odor and flavor of anise and fennel,anise myrtle (Myrtaceae),liquorice (Fabaceae),magnolia blossoms,and star anise (Schisandraceae). Closely related to anethole is its isomer estragole,which is abundant in tarragon (Asteraceae) and basil (Lamiaceae),and has a flavor reminiscent of anise. It is a colorless,fragrant,mildly volatile liquid. Anethole is only slightly soluble in water but exhibits high solubility in ethanol. This trait causes certain anise-flavored liqueurs to become opaque when diluted with water;this is called the ouzo effect.
Shikimic acid,more commonly known as its anionic form shikimate,is a cyclohexene,a cyclitol and a cyclohexanecarboxylic acid. It is an important biochemical metabolite in plants and microorganisms. Its name comes from the Japanese flower shikimi,from which it was first isolated in 1885 by Johan Fredrik Eykman. The elucidation of its structure was made nearly 50 years later.
Illicium anisatum,with common names Japanese star anise,Aniseed tree,and sacred Anise tree,known in Japanese as shikimi,is an evergreen shrub or small tree closely related to the Chinese star anise. Since it is highly toxic,the fruit is not edible;instead,the dried and powdered leaves are burned as incense in Japan. Its branches and evergreen leaves are considered highly sacred by Japanese Buddhists due to insects' aversion to them and their ability to remain fresh after pruning.
Illicium is a genus of flowering plants treated as part of the family Schisandraceae,or alternately as the sole genus of the Illiciaceae. It has a disjunct distribution,with most species native to eastern Asia and several in parts of North America,including the southeastern United States,Mexico,and the Caribbean. General common names include star anise and anisetree. The genus name comes from the Latin illicere.
Illiciaceae A.C.Sm. was a family of flowering plants recognized in a number of systems of plant taxonomy. The Illiciaceae is not recognized as a distinct family by the APG III system of plant taxonomy,the most well accepted system in use today.
Oseltamivir total synthesis concerns the total synthesis of the anti-influenza drug oseltamivir marketed by Hoffmann-La Roche under the trade name Tamiflu. Its commercial production starts from the biomolecule shikimic acid harvested from Chinese star anise and from recombinant E. coli. Control of stereochemistry is important:the molecule has three stereocenters and the sought-after isomer is only 1 of 8 stereoisomers.
Illicium floridanum is an evergreen shrub native to the Gulf Coast area of the Southern United States,from Florida to Louisiana.
Anisatin is an extremely toxic,insecticidally active component of the shikimi plant. The lethal dose is 1 mg/kg (i.p.) in mice. Symptoms begin to appear about 1–6 hours after ingestion,beginning with gastrointestinal ailments,such as diarrhea,vomiting,and stomach pain,followed by nervous system excitation,seizures,loss of consciousness,and respiratory paralysis,which is the ultimate cause of death.
Aminoshikimic acid is a synthetic crystalline carboxylic acid. It is characterized by multiple stereogenic centers and functional groups arrayed around a six-membered carbocyclic ring. Aminoshikimic acid is also an alternative to shikimic acid as a starting material for the synthesis of neuraminidase inhibitors such as the antiinfluenza agent oseltamivir (Tamiflu).
Merrilactone A is one of the four sesquiterpenes that were newly discovered from the fruit of Illicium merrillianum in 2000. Members of the genus Illicium include Chinese star anise,widely used as a spice for flavouring food and beverages,and also poisonous plants such as Japanese star anise. Chemical studies of Illicium have developed rapidly over the last 20 years,and merrilactone A has been shown to have neurotrophic activity in fetal rat cortical neuron cultures. This has led researchers to believe that Merrilactone A may hold therapeutic potential in the treatment of neuro-degenerative diseases such as Alzheimer's disease and Parkinson's disease.
Johan Fredrik Eykman or Johann Frederik Eijkman was a Dutch chemist.
Cumin is a flowering plant in the family Apiaceae,native to the Irano-Turanian Region. Its seeds –each one contained within a fruit,which is dried –are used in the cuisines of many cultures in both whole and ground form. Although cumin is used in traditional medicine,there is no high-quality evidence that it is safe or effective as a therapeutic agent.
Methoxyeugenol is a natural occurring allylbenzene and eugenol derivative. It is found in toxic Japanese star anise pericarp and leaves. as well as in nutmeg crude extract but not in nutmeg essential oil. It also activates PPAR-gamma in vivo.