2-phosphosulfolactate phosphatase

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2-phosphosulfolactate phosphatase
Identifiers
EC no. 3.1.3.71
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

The enzyme 2-phosphosulfolactate phosphatase [1] (EC 3.1.3.71) catalyzes the reaction

(2R)-2-phospho-3-sulfolactate + H2O (2R)-3-sulfolactate + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name (R)-2-phospho-3-sulfolactate phosphohydrolase. Other names in common use include (2R)-phosphosulfolactate phosphohydrolase, and ComB phosphatase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1VR0.

Related Research Articles

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<span class="mw-page-title-main">Acid phosphatase</span> Class of enzymes

Acid phosphatase is an enzyme that frees attached phosphoryl groups from other molecules during digestion. It can be further classified as a phosphomonoesterase. It is stored in lysosomes and functions when these fuse with endosomes, which are acidified while they function; therefore, it has an acid pH optimum. This enzyme is present in many animal and plant species.

In enzymology, a (R)-2-hydroxyacid dehydrogenase (EC 1.1.1.272) is an enzyme that catalyzes the chemical reaction

The enzyme phosphosulfolactate synthase catalyzes the reaction

The enzyme (2R)-sulfolactate sulfo-lyase catalyzes the reaction

In enzymology, a guanosine-5'-triphosphate,3'-diphosphate diphosphatase (EC 3.6.1.40) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Nucleoside-diphosphatase</span> Group of proteins having nucleoside-diphosphatase activity

In enzymology, a nucleoside-diphosphatase (EC 3.6.1.6) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">3'(2'),5'-bisphosphate nucleotidase</span> Class of enzymes

The enzyme 3′(2′),5′-bisphosphate nucleotidase (EC 3.1.3.7) catalyzes the reaction

The enzyme 4-nitrophenylphosphatase (EC 3.1.3.41) catalyzes the reaction

<span class="mw-page-title-main">Bisphosphoglycerate phosphatase</span>

In enzymology, a bisphosphoglycerate phosphatase (EC 3.1.3.13) is an enzyme that catalyzes the chemical reaction

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The enzyme methylphosphothioglycerate phosphatase (EC 3.1.3.14) catalyzes the reaction

<span class="mw-page-title-main">Phosphatidate phosphatase</span>

The enzyme phosphatidate phosphatase (PAP, EC 3.1.3.4) is a key regulatory enzyme in lipid metabolism, catalyzing the conversion of phosphatidate to diacylglycerol:

The enzyme phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase (EC 3.1.3.67) catalyzes the chemical reaction

The enzyme phosphatidylinositol-3-phosphatase (EC 3.1.3.64) catalyzes the reaction

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L-2-hydroxycarboxylate dehydrogenase (NAD<sup>+</sup>) Class of enzymes

L-2-hydroxycarboxylate dehydrogenase (NAD+) (EC 1.1.1.337, (R)-sulfolactate:NAD+ oxidoreductase, L-sulfolactate dehydrogenase, (R)-sulfolactate dehydrogenase, L-2-hydroxyacid dehydrogenase (NAD+), ComC) is an enzyme with systematic name (2S)-2-hydroxycarboxylate:NAD+ oxidoreductase. This enzyme catalyses the following chemical reaction

2,3-Bisphosphoglycerate 3-phosphatase (EC 3.1.3.80, MIPP1, 2,3-BPG 3-phosphatase) is an enzyme with systematic name 2,3-bisphospho-D-glycerate 3-phosphohydrolase. This enzyme catalyses the following reaction:

Glucosyl-3-phosphoglycerate phosphatase (EC 3.1.3.85, GpgP protein) is an enzyme with systematic name α-D-glucosyl-3-phospho-D-glycerate phosphohydrolase. This enzyme catalyses the following chemical reaction

References

  1. ↑ Graham DE, Graupner M, Xu H, White RH (2001). "Identification of coenzyme M biosynthetic 2-phosphosulfolactate phosphatase. A member of a new class of Mg2+-dependent acid phosphatases". Eur. J. Biochem. 268 (19): 5176–88. doi: 10.1046/j.0014-2956.2001.02451.x . PMID   11589710.


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