Aspergillus deoxyribonuclease K1

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Aspergillus deoxyribonuclease K1
Identifiers
EC no. 3.1.22.2
CAS no. 264922-12-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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NCBI proteins

Aspergillus deoxyribonuclease K1 (EC 3.1.22.2, Aspergillus DNase K1) is an enzyme. [1] [2] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products

This enzyme has preference for single-stranded DNA.

References

  1. Kato M, Ikeda Y (1968). "On the deoxyribonucleases, K1 and K2, isolated from mycelia of Aspergillus oryzae. I. Isolation and purification of DNases K1 and K2". J. Biochem. 64 (3): 321–8. doi:10.1093/oxfordjournals.jbchem.a128898. PMID   4303413.
  2. Shishido K, Kato M, Ikeda Y (1968). "Isolation of thymidylic acid-rich fragments from double-stranded deoxyribonucleic acids". J. Biochem. 65 (3): 479–481. doi:10.1093/oxfordjournals.jbchem.a129038.