The Chapacuran languages are a nearly extinct Native American language family of South America. Almost all Chapacuran languages are extinct, and the four that are extant are moribund. They are spoken in Rondônia in the southern Amazon Basin of Brazil and in northern Bolivia.
Munichi is a recently extinct language which was spoken in the village of Munichis, about 10 miles (16 km) west of Yurimaguas, Loreto Region, Peru. In 1988, there were two mother-tongue speakers, but they had not met since the 1970s. The last known fluent speaker, Victoria Huancho Icahuate, died in the late 1990s. As of 2009 there were several semi-speakers who retained significant lexical, and partial grammatical, knowledge of the language.
Tacanan is a family of languages spoken in Bolivia, with Ese’ejja also spoken in Peru. It may be related to the Panoan languages. Many of the languages are endangered.
The Nadahup languages, also known as Makú (Macú) or Vaupés–Japurá, form a small language family in Brazil, Colombia, and Venezuela. The name Makú is pejorative, being derived from an Arawakan word meaning "without speech". Nadahup is an acronym of the constituent languages.
Puquina is a small, putative language family, often portrayed as a language isolate, which consists of the extinct Puquina language and Kallawaya, although it is assumed that the latter is just a remnant of the former mixed with Quechuan. Puquina speakers are last mentioned in the early nineteenth century.
Yuracaré is an endangered language isolate of central Bolivia in Cochabamba and Beni departments spoken by the Yuracaré people.
The Cahuapanan languages are a language family spoken in the Amazon basin of northern Peru. They include two languages, Chayahuita and Jebero, which are spoken by more than 11,300 people. Chayahuita is spoken by most of that number, but Jebero is almost extinct.
Itonama is a moribund or extinct language isolate once spoken by the Itonama people in the Amazonian lowlands of north-eastern Bolivia. It was spoken on the Itonomas River and Lake in Beni Department.
Candoshi-Shapra is an indigenous American language isolate, spoken by several thousand people in western South America along the Chapuli, Huitoyacu, Pastaza, and Morona river valleys. There are two dialects, Chapara and Kandoashi (Kandozi). It is an official language of Peru, like other native languages in the areas in which they are spoken and are the predominant language in use. Around 88.5 percent of the speakers are bilingual with Spanish. The literacy rate in Candoshi-Shapra is 10 to 30 percent and 15 to 25 percent in the second language Spanish. There is a Candoshi-Shapra dictionary, and grammar rules have been codified.
Arutani is a nearly extinct language spoken in Roraima, Brazil and in the Karum River area of Bolivar State, Venezuela. There are only around 6 speakers left.
The Uru–Chipaya family is an indigenous language family of Bolivia.
Omurano is an unclassified language from Peru. It is also known as Humurana, Roamaina, Numurana, Umurano, and Mayna. The language was presumed to have become extinct by 1958, but in 2011 a rememberer was found who knew some 20 words in Omurano; he claimed that there were still people who could speak it.
The Rikbaktsa language, also spelled Aripaktsa, Erikbatsa or Erikpatsa and known ambiguously as Canoeiro, is a language spoken by the Rikbaktsa people of Mato Grosso, Brazil, that forms its own branch of the Macro-Gê languages.
Andaqui is an extinct language from the southern highlands of Colombia. It has been linked to the Paezan or Barbacoan languages, but no connections have been demonstrated. It was spoken by the Andaqui people of Colombia.
Culle, also spelled Culli, Cullí, or Kulyi, is a poorly attested extinct language of the Andean highlands of northern Peru. It is the original language of the highlands of La Libertad Region, the south of the Cajamarca Region (Cajabamba), and the north of the Ancash region. It is known through various word lists collected while the language was still spoken and through vocabulary loaned into the Spanish spoken in the region.
The extinct Hibito–Cholón or Cholónan languages form a proposed language family that links two languages of Peru, Hibito and Cholón, extinct as of 2000. They may also be related to the extinct Culle language, and perhaps to the language of the Chachapoya, but the data for all of these languages is poor.
Guató is a possible language isolate spoken by 1% of the Guató people of Brazil.
The Monde languages of Brazil form a branch of the Tupian language family.
Tequiraca (Tekiráka), also known as Abishira (Avishiri)* and Aiwa and Ixignor, is a language spoken in Peru. In 1925 there were between 50 and 80 speakers in Puerto Elvira on Lake Vacacocha. It is presumed extinct some time in the mid 20th century, though in 2008 two rememberers were found and 160 words and short sentences were recorded. Today, most ethnic Aiwa people have shifted to Kichwa and Spanish.
The Tiniwan languages are two extinct and one moribund language of Colombia that form a small family.
Bolivia 
