Farnesyl diphosphatase

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Farnesyl diphosphatase
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EC no. 3.1.7.6
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Farnesyl diphosphatase (EC 3.1.7.6, FPP phosphatase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase. [1] [2] It catalyses the reaction

(2E,6E)-farnesyl diphosphate + H2O (2E,6E)-farnesol + diphosphate

The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids.

Related Research Articles

Juvenile hormones (JHs) are a group of acyclic sesquiterpenoids that regulate many aspects of insect physiology. The first discovery of a JH was by Vincent Wigglesworth. JHs regulate development, reproduction, diapause, and polyphenisms. The chemical formula for juvenile hormone is .

The enzyme aristolochene synthase catalyzes the chemical reaction

The enzyme pentalenene synthase catalyzes the chemical reaction

In enzymology, a heptaprenyl diphosphate synthase is an enzyme that catalyzes the chemical reaction

Hexaprenyl-diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase . This enzyme catalyses the following chemical reaction

Ditrans,polycis-polyprenyl diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase . This enzyme catalyses the following chemical reaction

All-trans-decaprenyl-diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase . This enzyme catalyses the following chemical reaction

4,4'-diapophytoene synthase is an enzyme with systematic name farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase . This enzyme catalyses the following chemical reaction

Presqualene diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase . This enzyme catalyses the following chemical reaction

epi-Isozizaene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ( -epi-isozizaene-forming). This enzyme catalyses the following chemical reaction

β-Farnesene synthase (EC 4.2.3.47, farnesene synthase, terpene synthase 10, terpene synthase 10-B73, TPS10) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-β-farnesene-forming). This enzyme catalyses the following chemical reaction

(3R,6E)-nerolidol synthase (EC 4.2.3.49, terpene synthase 1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((3R,6E)-nerolidol-forming). This enzyme catalyses the following chemical reaction

(S)-β-bisabolene synthase (EC 4.2.3.55) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((S)-β-bisabolene-forming). This enzyme catalyses the following chemical reaction

cis-Muuroladiene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cis-muuroladiene-forming). This enzyme catalyses the following chemical reactions

Patchoulol synthase (EC 4.2.3.70) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (patchoulol-forming). This enzyme catalyses the following chemical reaction

Valencene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming). It is a terpene cyclase enzyme responsible for the biosynthesis of valencene, a sesquiterpene, using farnesyl pyrophosphate as its substrate. The first such enzyme was isolated using orange cDNA. This enzyme catalyses the following chemical reaction

β-Santalene synthase is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase . This enzyme catalyses the following chemical reaction

Cubebol synthase (EC 4.2.3.91, Cop4) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, cubebol-forming). This enzyme catalyses the following chemical reaction

δ-Guaiene synthase is an enzyme with systematic name (2E,6E))-farnesyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

β-Cubebene synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

References

  1. ↑ Song L (February 2006). "A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol". Applied Biochemistry and Biotechnology. 128 (2): 149–58. doi:10.1385/abab:128:2:149. PMID   16484724.
  2. ↑ Tsai SC, Gaylor JL (September 1966). "Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase". The Journal of Biological Chemistry. 241 (17): 4043–50. PMID   4288361.
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