Ribonuclease alpha

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Ribonuclease alpha
Identifiers
EC no. 3.1.26.2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

Ribonuclease alpha (EC 3.1.26.2, 2'-O-methyl RNase) is an enzyme. [1] This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage to 5'-phosphomonoester

This enzyme is specific for O-methylated RNA.

References

  1. Norton J, Roth JS (May 1967). "A ribonuclease specific for 2'-O-methylated ribonucleic acid". The Journal of Biological Chemistry. 242 (9): 2029–34. doi: 10.1016/S0021-9258(18)96012-6 . PMID   6022850.