| 2022 Georgia's Rome Challenger | |
|---|---|
| Date | 11–17 July |
| Edition | 1st |
| Surface | Hard (indoor) |
| Location | Rome, Georgia, United States |
| Champions | |
| Singles | |
 Wu Yibing | |
| Doubles | |
 Enzo Couacaud /  Andrew Harris | |
The 2022 Georgia's Rome Challenger was a professional tennis tournament played on indoor hard courts. It was the first edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Rome, Georgia, United States between July 11 and July 17, 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 JPN | Yoshihito Nishioka | 101 | 1 |
 USA | J. J. Wolf | 116 | 2 |
 ECU | Emilio Gómez | 151 | 3 |
 ARG | Juan Pablo Ficovich | 163 | 4 |
 CRO | Borna Gojo | 174 | 5 |
| USA | Michael Mmoh | 177 | 6 |
| USA | Bjorn Fratangelo | 196 | 7 |
| FRA | Enzo Couacaud | 206 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as a special exempt:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Wu Yibing def. Ben Shelton 7–5, 6–3. Enzo Couacaud / Andrew Harris def. 
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