| 2022 Open du Pays d'Aix | |
|---|---|
| Date | 2–8 May |
| Edition | 9th |
| Surface | Clay |
| Location | Aix-en-Provence, France |
| Champions | |
| Singles | |
 Benjamin Bonzi | |
| Doubles | |
| Titouan Droguet / Kyrian Jacquet | |
The 2022 Open du Pays d'Aix was a professional tennis tournament played on clay courts. It was the ninth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Aix-en-Provence, France between 2 and 8 May 2022.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| FRA | Benjamin Bonzi | 58 | 1 |
 GER | Daniel Altmaier | 67 | 2 |
| FRA | Richard Gasquet | 80 | 3 |
| FRA | Quentin Halys | 102 | 4 |
 URU | Pablo Cuevas | 107 | 5 |
 PER | Juan Pablo Varillas | 111 | 6 |
 ESP | Fernando Verdasco | 118 | 7 |
| FRA | Corentin Moutet | 120 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Benjamin Bonzi def. Grégoire Barrère 6–2, 6–4. Titouan Droguet / Kyrian Jacquet def. 
Nicolás Barrientos / 
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