Virtopsy

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Virtopsy is a virtual alternative to a traditional autopsy, conducted with scanning and imaging technology. The name is a portmanteau of "virtual" and "autopsy" and is a trademark registered to Richard Dirnhofer, the former head of the Institute of Forensic Medicine of the University of Bern, Switzerland. [1] [2]

Contents

Dirnhofer has proposed virtopsy as a partial or complete replacement for traditional autopsy, [3] and he has asserted that virtopsy fully satisfies the requirement that medical forensic findings provide “a complete and true picture of the object examined”.[ This quote needs a citation ] Furthermore, virtopsy is said to achieve the objective “that the pathologist’s report should ‘photograph’ with words so that the reader is able to follow his thoughts visually”.[ This quote needs a citation ]

Concept

Virtopsy employs imaging methods that are also used in clinical medicine such as computed tomography (CT) scans and magnetic resonance imaging (MRI). [4] Also, 3D body surface scanning is used to integrate body surface documentation with 3D scene or tool scans. The choice of methods is further supplemented with 3D imaging-guided biopsy systems [5] and post-mortem angiography. [6]

CT is well suited to show foreign objects, bone and air or gas distribution throughout the body, whereas MRI sequences are strong in detailing organ and soft tissue findings. A comprehensive analysis of both surface and deep tissue findings may require fusion of CT, MRI and 3D surface data. [7]

Resulting data can be archived and reproduced without loss, [8] analysed elsewhere, or distributed to specialists for technically demanding analysis.

Because traditional autopsies can produce both different and additional findings compared to virtopsies, virtopsy is not a generally accepted method to entirely replace autopsies. [9] In fact, the first scientific study detailing the results of comparing postmortem CT scanning with conventional autopsies concluded that single methods were not as useful as the combination of scanning and autopsy were. [10]

Terms

The term “Virtobot” is a trademark also registered to Prof. R. Dirnhofer. It describes a multi-functional robotic system. [5]

The "Virtangio" machine is a device that is trademarked to Prof. R. Dirnhofer [11] and manufactured by Fumedica . [12]

Operative aspects

With Prof. Michael Thali as operative head of the group, the virtopsy research team has operated out of the Institute of Forensic Medicine at the University of Zurich, Switzerland since early 2011. [13]

Examination of death

The idea to conduct virtual autopsy is not new. In 2003, the British Museum contacted the Institute of Forensic Medicine for their help performing a virtopsy on a 3000-year-old mummy named Nesperennub, as an autopsy could not be done without compromising the body. [14] While manner of death, [4] cause of death, [4] time of death, [15] [16] identification of deceased and a range of practical and reconstructive applications are obviously related to medicolegal investigation of death, virtopsy methods were ground breaking in that they have established a new high-tech toolbox into both research and practice morphological investigation aspects of modern forensic pathology.

Since virtopsy is non-invasive, it can be less traumatic for surviving family members and may not violate religious taboos against violating bodily integrity. [17]

Examination of the living

Non-invasive imaging is also conducted in living or surviving subjects, but as that has been the main clinical application of CT and MR imaging to begin with, their use in medicolegal investigation of the living is not as ground breaking as using them for investigation of death. Nevertheless, a number of applications that may be regarded as specific for medicolegal imaging applications in the living have found attraction for virtopsy-derived methods:

Technology

The technology currently used for conducting a “virtual autopsy” comprises

Virtopsy objectives

The virtopsy idea was generated to yield results along a comprehensive number of performance indicators:

Advantages

This method offers the following advantages:

Disadvantages

Best practice

The National Research Council in the USA, as part of its proposals for reforms in the forensic sciences, has proposed virtopsy as “Best Practice” for the gathering of forensic evidence. [21]

In addition, the International Society of Forensic Radiology and Imaging was founded in 2012 with the aim of enabling a continuous exchange of research results among its members and developing quality standards for the techniques employed.[ citation needed ]

A Technical Working Group Forensic Imaging Methods was founded in 2005 by Michael Thali and Richard Dirnhofer. It aims to promote an increasingly internationally standardised approach.[ citation needed ]

Furthermore, a Technical Working Group Postmortem Angiography Methods was founded in 2012 to promote best practice. Under the direction of the University Hospital of Lausanne and comprising nine European institutes of forensic medicine, it is developing reliable, standardized methods and guidelines for conducting and assessing postmortem angiographic examinations.[ citation needed ]

Virtopsy project leading house

Institutes contributing to the Virtopsy project

Institutes, districts or countries conducting post-mortem scanning

Films

Books and journals

Related Research Articles

<span class="mw-page-title-main">Magnetic resonance imaging</span> Medical imaging technique

Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from computed tomography (CT) and positron emission tomography (PET) scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy.

<span class="mw-page-title-main">Positron emission tomography</span> Medical imaging technique

Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body.

<span class="mw-page-title-main">CT scan</span> Medical imaging procedure using X-rays to produce cross-sectional images

A computed tomography scan, formerly called computed axial tomography scan, is a medical imaging technique used to obtain detailed internal images of the body. The personnel that perform CT scans are called radiographers or radiology technologists.

<span class="mw-page-title-main">Radiology</span> Branch of medicine specialising in medical imaging

Radiology is the medical specialty that uses medical imaging to diagnose diseases and guide treatment within the bodies of humans and other animals. It began with radiography, but today it includes all imaging modalities. This includes technologies that use no ionizing electromagnetic radiation, such as ultrasonography and magnetic resonance imaging), as well as others that do use radiation, such as computed tomography (CT), fluoroscopy, and nuclear medicine including positron emission tomography (PET). Interventional radiology is the performance of usually minimally invasive medical procedures with the guidance of imaging technologies such as those mentioned above.

<span class="mw-page-title-main">Medical imaging</span> Technique and process of creating visual representations of the interior of a body

Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging.

<span class="mw-page-title-main">Autopsy</span> Medical examination of a corpse

An autopsy is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death; or the exam may be performed to evaluate any disease or injury that may be present for research or educational purposes. The term necropsy is generally used for non-human animals.

<span class="mw-page-title-main">Nuclear medicine</span> Medical specialty

Nuclear medicine, is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear imaging is, in a sense, radiology done inside out, because it records radiation emitted from within the body rather than radiation that is transmitted through the body from external sources like X-ray generators. In addition, nuclear medicine scans differ from radiology, as the emphasis is not on imaging anatomy, but on the function. For such reason, it is called a physiological imaging modality. Single photon emission computed tomography (SPECT) and positron emission tomography (PET) scans are the two most common imaging modalities in nuclear medicine.

<span class="mw-page-title-main">Tomography</span> Imaging by sections or sectioning using a penetrative wave

Tomography is imaging by sections or sectioning that uses any kind of penetrating wave. The method is used in radiology, archaeology, biology, atmospheric science, geophysics, oceanography, plasma physics, materials science, cosmochemistry, astrophysics, quantum information, and other areas of science. The word tomography is derived from Ancient Greek τόμος tomos, "slice, section" and γράφω graphō, "to write" or, in this context as well, "to describe." A device used in tomography is called a tomograph, while the image produced is a tomogram.

<span class="mw-page-title-main">Angiography</span> Medical imaging technique

Angiography or arteriography is a medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers. Modern angiography is performed by injecting a radio-opaque contrast agent into the blood vessel and imaging using X-ray based techniques such as fluoroscopy. With time-of-flight (TOF) magnetic ressonance it is no longer necessary to use a contrast.

Neuroimaging is a medical technique that allows doctors and researchers to take pictures of the inner workings of the body or brain of a patient. It can show areas with heightened activity, areas with high or low blood flow, the structure of the patients brain/body, as well as certain abnormalities. Neuroimaging is most often used to find the specific location of certain diseases or birth defects such as tumors, cancers, or clogged arteries. Neuroimaging first came about as a medical technique in the 1880s with the invention of the human circulation balance and has since lead to other inventions such as the x-ray, air ventriculography, cerebral angiography, PET/SPECT scans, magnetoencephalography, and xenon CT scanning.

<span class="mw-page-title-main">Neuroimaging</span> Set of techniques to measure and visualize aspects of the nervous system

Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative research studies of brain disease and psychiatric illness. Neuroimaging is highly multidisciplinary involving neuroscience, computer science, psychology and statistics, and is not a medical specialty. Neuroimaging is sometimes confused with neuroradiology.

Willi A. Kalender was a German medical physicist and professor and former chairman of the Institute of Medical Physics of the University of Erlangen-Nuremberg. Kalender has produced several new technologies in the field of diagnostic radiology imaging.

<span class="mw-page-title-main">PET-MRI</span> Medical diagnostic method

Positron emission tomography–magnetic resonance imaging (PET–MRI) is a hybrid imaging technology that incorporates magnetic resonance imaging (MRI) soft tissue morphological imaging and positron emission tomography (PET) functional imaging.

<span class="mw-page-title-main">Cone beam computed tomography</span> Medical imaging technique

Cone beam computed tomography is a medical imaging technique consisting of X-ray computed tomography where the X-rays are divergent, forming a cone.

<span class="mw-page-title-main">Magnetic resonance imaging of the brain</span>

Magnetic resonance imaging of the brain uses magnetic resonance imaging (MRI) to produce high-quality two- or three-dimensional images of the brain, brainstem, and cerebellum without ionizing radiation (X-rays) or radioactive tracers.

<span class="mw-page-title-main">Computed tomography of the head</span> Cross-sectional X-rays of the head

Computed tomography of the head uses a series of X-rays in a CT scan of the head taken from many different directions; the resulting data is transformed into a series of cross sections of the brain using a computer program. CT images of the head are used to investigate and diagnose brain injuries and other neurological conditions, as well as other conditions involving the skull or sinuses; it used to guide some brain surgery procedures as well. CT scans expose the person getting them to ionizing radiation which has a risk of eventually causing cancer; some people have allergic reactions to contrast agents that are used in some CT procedures.

A medical animation is a short educational film, usually based around a physiological or surgical topic, that is rendered using 3D computer graphics. While it may be intended for an array of audiences, the medical animation is most commonly utilized as an instructional tool for medical professionals or their patients.

<span class="mw-page-title-main">Forensic radiology</span>

Forensic radiology is the discipline which comprises the performance, interpretation and reportage of the radiological examinations and procedures which are needed in court procedures or law enforcement. Radiological methods are widely used in identification, age estimation and establishing cause of death. Comparison of ante mortem and post mortem radiographs is one of the means of identification. The scanning of baggage, vehicles and individuals have many applications.

A digital autopsy is a non-invasive autopsy in which digital imaging technology, such as with computerized tomography (CT) or magnetic resonance imaging (MRI) scans, is used to develop three-dimensional images for a virtual exploration of a human body.

<span class="mw-page-title-main">Paleoradiology</span> Study of archaeological remains through the use of radiographic techniques

Paleoradiology is the study of archaeological remains through the use of radiographic techniques, such as X-ray, CT and micro-CT scans. It is predominately used by archaeologists and anthropologists to examine mummified remains due to its non-invasive nature. Paleoradiologists can discover post-mortem damage to the body, or any artefacts buried with them, while still keeping the remains intact. Radiological images can also contribute evidence about the person's life, such as their age and cause of death. The first recorded use of paleoradiology was in 1896, just a year after the Rōntgen radiograph was first produced. Although this method of viewing ancient remains is advantageous due to its non-invasive manner, many radiologists lack expertise in archeology and very few radiologists can identify ancient diseases which may be present.

References

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