PNU-91356A

Last updated
PNU-91356A
PNU91356A structure.png
Clinical data
ATC code
  • none
Identifiers
  • (10R)-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
CAS Number
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C13H17N3O
Molar mass 231.299 g·mol−1
3D model (JSmol)
  • CCCNC1CC2=C3C(=CC=C2)NC(=O)N3C1
  • InChI=1S/C13H17N3O/c1-2-6-14-10-7-9-4-3-5-11-12(9)16(8-10)13(17)15-11/h3-5,10,14H,2,6-8H2,1H3,(H,15,17)/t10-/m1/s1
  • Key:XTWUNLMHXDDOMD-SNVBAGLBSA-N

PNU-91356A (U-91356) is a drug used in scientific research which acts as a potent and reasonably selective agonist of the dopamine receptor D2, with lower affinity for the related D3 and D4 subtypes and the 5-HT1A receptor. [1] [2]

See also

References

  1. ↑ Moon MW, Morris JK, Heier RF, Hsi RS, Manis MO, Royer ME, et al. (1993). "Medicinal chemistry of imidazoquinolinone dopamine receptor agonists". Drug Design and Discovery. 9 (3–4): 313–22. PMID   8104520.
  2. ↑ Piercey MF, Moon MW, Sethy VH, Schreur PJ, Smith MW, Tang AH, Von Voigtlander PF (December 1996). "Pharmacology of U-91356A, an agonist for the dopamine D2 receptor subtype". European Journal of Pharmacology. 317 (1): 29–38. doi:10.1016/s0014-2999(96)00695-4. PMID   8982716.


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