DNAJC14

DNAJC14
Identifiers
Aliases	DNAJC14 , DNAJ, DRIP78, HDJ3, LIP6, DnaJ heat shock protein family (Hsp40) member C14
External IDs	OMIM: 606092; MGI: 1921580; HomoloGene: 12553; GeneCards: DNAJC14; OMA:DNAJC14 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.2 Start 55,820,960 bp [1] End 55,830,824 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 D3 Start 128,639,931 bp [2] End 128,655,315 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans mucosa of ileum stromal cell of endometrium granulocyte smooth muscle tissue monocyte tibialis anterior muscle appendix rectum prefrontal cortex Top expressed in lacrimal gland primary oocyte secondary oocyte granulocyte right lung lobe external carotid artery internal carotid artery lip zygote tail of embryo More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor binding dopamine receptor binding Cellular component integral component of membrane endoplasmic reticulum membrane membrane extracellular exosome endoplasmic reticulum Biological process protein transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 85406 74330 Ensembl ENSG00000135392 ENSMUSG00000025354 UniProt Q6Y2X3 Q921R4 RefSeq (mRNA) NM_032364 NM_028873 NM_001359824 NM_001359825 RefSeq (protein) NP_115740 NP_083149 NP_001346753 NP_001346754 Location (UCSC) Chr 12: 55.82 – 55.83 Mb Chr 10: 128.64 – 128.66 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

DnaJ homolog subfamily C member 14 is a protein that in humans is encoded by the DNAJC14 gene. ^{[5] [6] [7]}

Interactions

DNAJC14 has been shown to interact with Dopamine receptor D1. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000135392 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025354 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bermak JC, Li M, Bullock C, Zhou QY (May 2001). "Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein". Nat Cell Biol. 3 (5): 492–8. doi:10.1038/35074561. PMID   11331877. S2CID   40809366.
6. Tchernev VT, Mansfield TA, Giot L, Kumar AM, Nandabalan K, Li Y, Mishra VS, Detter JC, Rothberg JM, Wallace MR, Southwick FS, Kingsmore SF (May 2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Mol Med. 8 (1): 56–64. doi:10.1007/bf03402003. PMC   2039936 . PMID   11984006.
7. "Entrez Gene: DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14".

Further reading

• Bermak JC, Zhou QY (2004). "Accessory proteins in the biogenesis of G protein-coupled receptors". Mol. Interv. 1 (5): 282–7. PMID   14993367.
• Leclerc PC, Auger-Messier M, Lanctot PM, et al. (2002). "A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling". Endocrinology. 143 (12): 4702–10. doi: 10.1210/en.2002-220679 . PMID   12446598.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Chen J, Huang Y, Wu H, et al. (2003). "Molecular cloning and characterization of a novel human J-domain protein gene (HDJ3) from the fetal brain". J. Hum. Genet. 48 (5): 217–21. doi: 10.1007/s10038-003-0012-8 . PMID   12768437.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.